122 research outputs found

    2014 Proceedings: Music and Art Instruction

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    Promotion of Religion and Values or Just an Added Value to Higher Education?https://knowledge.e.southern.edu/reysymp/1002/thumbnail.jp

    The pancreas in human type 1 diabetes

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    Type 1 diabetes (T1D) is considered a disorder whose pathogenesis is autoimmune in origin, a notion drawn in large part from studies of human pancreata performed as far back as the 1960s. While studies of the genetics, epidemiology, and peripheral immunity in T1D have been subject to widespread analysis over the ensuing decades, efforts to understand the disorder through analysis of human pancreata have been far more limited. We have reviewed the published literature pertaining to the pathology of the human pancreas throughout all stages in the natural history of T1D. This effort uncovered a series of findings that challenge many dogmas ascribed to T1D and revealed data suggesting the marked heterogeneity in terms of its pathology. An improved understanding and appreciation for pancreatic pathology in T1D could lead to improved disease classification, an understanding of why the disorder occurs, and better therapies for disease prevention and management

    Investigation of a Half-Conical Scoop Inlet Mounted at Five Alternate Circumferential Locations around a Circular Fuselage Pressure-Recovery Results at a Mach Number 2.01

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    The effects of inlet circumferential position around the fuselage on the characteristics of a half-conical scoop inlet having a 24.6deg half-angle cone have been investigated in the langley 4- by 4-foot supersonic pressure tunnel. Pressure-recovery results have been obtained at a Mach number of 2.01 for a fixed boundary-layer-bleed height which was 60 percent of the boundary-layer thickness at an angle of attack of 0deg, and for cowling position parameters of 42.4deg and 38.0deg. inlet had a capture area equal to 24.9 percent of the basic-fuselage frontal area. The angle of attack was varied from 0deg to 12deg. The most favorable pressure-recovery characteristics at angles of attack were obtained with the Inlet located on the bottom of the fuselage where the maximum recovery increased from a value of 81 percent at an angle of attack of 0deg to 87 percent at 12deg. In general, the pressure recovery decreased with increasing angle of attack for all other inlet locations. At a given angle of attack the pressure recovery decreased as the inlet location was progressively moved from the bottom to the top of the fuselage. Stable subcritical operation of the inlet with nearly constant pressure recovery was obtained for inlet mass-flow ratios from 1.0 to about 0.76 at an angle of attack of 0deg with the central body in the design position

    An endoplasmic reticulum-specific cyclophilin.

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