The Role of the Mediterranean Diet in the Prevention of Deep Vein Thrombosis

Since anticoagulation performed by affecting hematological parameters has serious complications such as bleeding, studies are also conducted to benefit from diets instead of prophylactic anticoagulants in order to reduce the risk of developing venous thromboembolism (VTE). Our aim is to review the benefits of the Mediterranean diet in the prophylaxis and treatment of deep vein thrombosis (DVT), although the current studies have yet to be conclusive. The Mediterranean diet is characterized by the consumption of plant-based foods such as vegetables, fruits, nuts, legumes and unprocessed cereals, and seafood such as fish. The consumption of meat and meat products is low in this diet. The consumption of dairy products is also low. Fruits, vegetables and juices in the Mediterranean diet contain a significant amount of flavonoids. In addition, olive oil, which is one of the basic elements of the Mediterranean diet, has antioxidant properties due to its essential polyphenolic compounds. It has been reported that the low consumption of vegetables contributes to the increase of VTE incidence in Thai society. On the contrary, a diet with plenty of herbal food, fish and a small amount of red meat (Mediterranean diet) has been reported to reduce the risk of VTE. We think that the Mediterranean diet, which is beneficial for our health, may also decrease the risk of DVT. However, medical therapy is required for the treatment of patients with DVT. Nutritional approaches, including the Mediterranean diet, should be considered as supplement

Management of Cardiac Tamponade: A Comperative Study between Echo-Guided Pericardiocentesis and Surgery—A Report of 100 Patients

Background. Cardiac tamponade (CT) represents a life-threatening condition, and the optimal method of draining accumulated pericardial fluid remains controversial. We have reviewed 100 patients with CT at our institution over a five-year period and compared the results of echo-guided pericardiocentesis, primary surgical treatment, and surgical treatment following pericardiocentesis with regard to functional outcomes. Methods. The study group consisted of 100 patients with CT attending Yuzuncu Yil University from January 2005 to January 2010 who underwent one of the 3 treatment options (echo-guided pericardiocentesis, primary surgical treatment, and surgical treatment following pericardiocentesis). CT was defined by clinical and echocardiographic criteria. Data on medical history, characteristics of the pericardial fluid, treatment strategy, and follow-up data were collected. Results. Echo-guided pericardiocentesis was performed in 38 (38%) patients (Group A), primary surgical treatment was preformed in 36 (36%) patients (Group B), and surgical treatment following pericardiocentesis was performed in 26 (26%) patients (Group C). Idiopathic and malignant diseases were primary cause of tamponade (28% and 28%, resp.), followed by tuberculosis (14%). Total complication rates, 30-day mortality, and total mortality rates were highest in Group C. Recurrence of tamponade before 90 days was highest in Group A. Conclusions. According to our results, minimal invasive procedure echo-guided pericardiocentesis should be the first choice because of lower complication and mortality rates especially in idiopathic cases and in patients with hemodynamic instability. Surgical approach might be performed for traumatic cases, purulent, recurrent, or malign effusions with higher complication and mortality rates

Abdülmecid Han Fountain and Cistern and the Inscription of the Halid Ağa Fountain, Unearthed in Haydarpasha

1839 yılında Sultan Abdülmecid’in ihya ettiği Halid Ağa Çeşmesi’nin adı değiştirilerek Abdülmecid Han Çeşmesi olmuştur. 1902 senesinde günümüzdeki Haydarpaşa’daki yerine taşınmış ve çeşme zamanla yol kotu altında kalmıştır. Haydarpaşa Tren İstasyonu alanında, “Marmaray Projesi Gebze-Halkalı Banliyö Hattı İyileştirmesi” kapsamında, İstanbul Arkeoloji Müzeleri denetiminde 2018 senesinde “Haydarpaşa Garı Arkeolojik Kazıları” başlatılmıştır. Kazı çalışmaları sırasında çeşmenin taşınmadan evvelki yerinden Halid Ağa Çeşmesi Kitâbesi bulunmuştur. Tıbbiye Köprüsü G1 ayağının inşası sırasında ise Haydarpaşa’daki mevcut yerinden Abdülmecid Han Çeşmesi ve Sarnıcı ortaya çıkarılmıştır. Tüm bu çalışmalar sayesinde gün ışığına çıkarılan bu eserler kültürel bir miras olarak kentsel dokuya tekrar kazandırılmıştır. Bu çalışmanın literatüre katkısı, çeşmenin yapım tarihinden günümüze kadar geçirdiği tüm değişimlerin belge ve haritalarla tespit edilmesidir. Çeşme, çağdaş örnekleri ile süsleme detayları açısından karşılaştırılmış, ölçü ve yapısal özellikleri tanımlanarak araştırmacılara veri oluşturmuştur. Zamanla işlevini kaybeden çeşmenin yeniden ortaya çıkarılması ile koruma sorunları değerlendirilmiştir.In 1839, the name of the Halid Ağa Fountain, which was restored by Sultan Abdülmecid, was changed into Abdülmecid Han Fountain. It was moved to its current location in Haydarpasha in 1902 and over the time the fountain remained below the road level . In the area of Haydarpaşa Train Station, “Haydarpasha Train Station Archaeological Excavations” was started in 2018 under the supervision of Istanbul Archeology Museums, within the scope of “Marmaray Project Gebze-Halkalı Suburban Line Improvement”. During the excavations, the Halid Ağa Fountain Inscription was found in the place before the fountain was moved. During the construction of the Tıbbiye Bridge G1 pillar, Abdülmecid Han Fountain and Cistern were unearthed from its current location in Haydarpaşa. Thanks to all these works, which were brought to light, were brought back to the urban fabric as a cultural heritage. The contribution of this study to the literature is to identify all the changes that the fountain has undergone from the date of its construction to the present day, with documents and maps. The fountain was compared with its contemporary examples in terms of ornamental details, its size, and the structural features were defined and data were created for researchers. Conservation problems were evaluated with the re-discovery of the fountain, which lost its function over time

Roles of the Oxidative Stress and ADMA in the Development of Deep Venous Thrombosis

Venous thromboembolism has multifactorial origin and occurs in the context of complex interactions between environmental and genetic predisposing factors. Oxidative stress plays an important role in the physiopathology of venous thrombosis. Current study examined the role of oxidative stress and asymmetric dimethylarginine in the development of DVT with the parameters such as serum malondialdehyde (MDA), glutathione peroxidase (GSH-Px), catalase, ADMA, homocysteine, folic acid, vitamin B6, and vitamin B12 levels. Serum MDA levels were found significantly (P0.05). This study showed that patients with DVT have increased oxidative stress compared with the healthy volunteers whereas there was no significant difference between the groups in terms of serum ADMA levels. Thus serum ADMA levels seemed to be not related with development of DVT

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Background. Cardiac tamponade (CT) represents a life-threatening condition, and the optimal method of draining accumulated pericardial fluid remains controversial. We have reviewed 100 patients with CT at our institution over a five-year period and compared the results of echo-guided pericardiocentesis, primary surgical treatment, and surgical treatment following pericardiocentesis with regard to functional outcomes. Methods. The study group consisted of 100 patients with CT attending Yuzuncu Yil University from January 2005 to January 2010 who underwent one of the 3 treatment options (echo-guided pericardiocentesis, primary surgical treatment, and surgical treatment following pericardiocentesis). CT was defined by clinical and echocardiographic criteria. Data on medical history, characteristics of the pericardial fluid, treatment strategy, and followup data were collected. Results. Echo-guided pericardiocentesis was performed in 38 (38%) patients (Group A), primary surgical treatment was preformed in 36 (36%) patients (Group B), and surgical treatment following pericardiocentesis was performed in 26 (26%) patients (Group C). Idiopathic and malignant diseases were primary cause of tamponade (28% and 28%, resp.), followed by tuberculosis (14%). Total complication rates, 30-day mortality, and total mortality rates were highest in Group C. Recurrence of tamponade before 90 days was highest in Group A. Conclusions. According to our results, minimal invasive procedure echo-guided pericardiocentesis should be the first choice because of lower complication and mortality rates especially in idiopathic cases and in patients with hemodynamic instability. Surgical approach might be performed for traumatic cases, purulent, recurrent, or malign effusions with higher complication and mortality rates

Evaluation of intraocular pressure and retinal nerve fiber layer thickness in patients with Helicobacter pylori

Objectives: High prevalence of Helicobacter pylori (HP) in the glaucoma patients was shown in recent studies. In our prospective study we aimed to compare the intraocular pressure (IOP) and the retinal nerve fiber layer thickness (RNFLT) in patients with HP positive and negative. Methods: In 91 patients with gastritis HP was investigated by urea breath test (UBT) and biopsy sample culture Following the full ophthalmologic examination the patients’ IOP was measured by Goldmann applanation tonometry and RNFLT was measured by spectral optic coherence tomography. The patients' demographic and clinical characteristics were compared with the χ² test for categorical variables and with the Mann Whitney U test for continuous variables. Results: Of the 90 patients who meet the including criteria, HP was detected in 74 patients (27 male, 47 female) positive, and in 16 patients (7 male, 9 female) negative. Median (minimum-maximum) age values were 46 (18-79) in HP positive group and 51 (18-67) in HP negative group. One hundred forty seven eyes in 74 HP positive patients and 31 eyes in 16 HP negative patients included in the study. Median IOP values were determined 14 (7-21) mmHg in HP positive group and 14 (8-18) mmHg in HP negative group. The measurements of RNFLT in superior, temporal, inferior and nasal quadrants found to be respectively 122(98-165), 68(50-101), 135(93-188), 79(51-120) micron in HP positive group and 120(94-161), 67(43-104), 129(94-166), 76(50-97) micron in HP negative group. No statistically significant difference was found when compared IOP and RNFLT measurements between the two groups (p<0.05). Conclusion: In this study found that the IOP and RNFLT measurements of HP positive group was not show statistically significant difference compared with HP negative group. In a large case series, randomized, case-controlled, histologic and serologic studies should be done to show the relationship between HP and glaucoma