Growth and Yield of Hybrid Maize as Influenced by Fertilizer Management

An experiment was carried out at the Agronomy Field Laboratory, Department of Agronomy, Hajee Mohammad Danesh Science and Technology University, Bangladesh during the rabi season (December to May), 2012-13 to study the effect of different organic and inorganic fertilizers on growth and development of hybrid maize (Denali). The experiment was laid out in Randomized Complete block Design with three replications with 30 plots. Ten fertilizer treatments (T1= Compost, T2= Cow dung, T3= Poultry manure, T4= Recommended fertilizer dose, T5= Compost + Half recommended fertilizer dose, T6= Compost + Full recommended fertilizer dose, T7= Cow dung + Half recommended fertilizer dose, T8= Cow dung + Full recommended fertilizer dose, T9= Poultry manure + Half recommended fertilizer dose, T10= Poultry manure + Full recommended fertilizer dose. The recommended fertilizer dose was 500 Kg ha-1 urea + 250 Kg ha-1 TSP + 200 Kg ha-1 MP + 15 Kg ha-1 ZnSO4 + 6 Kg ha-1 Boric Acid. And the rate of Compost, Cow dung and Poultry manure was 10t/ha. The effect of different manure and fertilizer doses on the yield and yield attributes were significant. The plant height, number of leaves per plant, weight of stem per plant, weight of leaves per plant, length of cob, grain weight per cob, diameter of cob, no. of grains per row, no. of total grains per cob, 1000-grain weight, yield plant-1, yield ha-1 were significantly affected by different manures and fertilizer uses with different doses. The treatments T1, T2, T3, T4, T5, T6, T7, T8, T9 and T10 gave grain yield 10.16, 9.09, 8.49, 14.34, 13.35, 18.12, 11.99, 17.09, 11.40 and 15.98 t ha-1, respectively. The T6 Treatment gave higher grain yield (18.12) t ha-1 and the T3 treatment performed lowest grain yield (8.49 t ha-1). The application of compost and full dose fertilizer is higher yielding. Balance nutrition with enough organic matter enrichment of the soil is the cause of this result

Mitral anular disjunction ve mitral kapak prolapsusu olan bir hastada cerrahi tamir sonrası sürekli olmayan ventriküler taşikardinin kaybolması

Mitral annular disjunction (MAD) is a structural abnormality defined as the separation of the ventricular myocardium between the mitral valve annulus and the left atrial wall. It is present in some patients with mitral valve prolapse (MVP) and is associated with papillary muscle fibrosis and ventricular arrhythmia. Although it is easy to diagnose, it can be overlooked in daily practice. This study presents the case of a 42-year-old patient who was admitted to the cardiology clinic with complaints of palpitation and syncope. The patient was diagnosed with bileaflet MVP, MAD, and severe mitral regurgitation using transthoracic echocardiography and cardiac magnetic resonance imaging, in which ventricular tachycardia disappeared following subsequent surgical repair.Mitral anular disjunction (MAD), mitral kapak anulusu ile sol atriyal duvar arasında ventrikülün miyokarddan ayrılması olarak tanımlanan yapısal bir anormalliktir. MAD, mitral valv prolapsusu (MVP) olan hastaların bir kısmında bulunmakta olup MVP’den bağımsız olarak papiller kas fibrozu ve ventriküler aritmi ile ilişkilidir. Tanısı kolay olmasına rağmen günlük pratikte büyük oranda akla gelmemesi nedeniyle gözden kaçabilmektedir. Bu olguda, çarpıntı ve senkop şikayeti ile kardiyoloji kliniğine başvuran, transtorasik ekokardiyografi ve kardiyak manyetik rezonans görüntüleme ile biliflet MVP, MAD ve ileri mitral yetersizliği tespit edilen ve cerrahi tamir sonrasında ventriküler taşikardinin kaybolduğu 42 yaşındaki olguyu sunmayı amaçladık

Effect of Empagliflozin Treatment on Ventricular Repolarization Parameters

Background: An example of a sodium-glucose cotransporter-2 (SGLT-2) inhibitor is Empagliflozin. It is a new medicine for treating type 2 diabetes mellitus (T2DM), but there is increasing interest in how empagliflozin affects the heart. This study aims to examine the impact of empagliflozin treatment on ventricular repolarization parameters in T2DM patients. Methods: T2DM patients were included in a prospective study. Measurements of ventricular repolarization parameters, including QT interval, corrected QT interval (QTc), QT dispersion (QTd), Tpeak-to-Tend interval (Tp-e), and Tpeak-to-Tend interval corrected for QTc (Tp-e/QTc), were obtained before initiating empagliflozin treatment and six months following treatment initiation. Statistical analysis was performed to assess changes in these parameters. Results: In this study, 95 patients were diagnosed with T2DM out of 177 patients. Among T2DM patients, 40 were male (42%) compared to 48% males in controls (p = 0.152). The average age of the T2DM patients was 60.2 ± 9.0 years, compared to 58.2 ± 9.2 years in the control group (p = 0.374). When comparing pre- and post-treatment measurements of parameters representing ventricular repolarization (QT 408.5 ± 22.9/378.8 ± 14.1, p < 0.001; QTc 427.0 ± 20.5/404.7 ± 13.8, p < 0.001; QTd 52.1 ± 1.2/47.8 ± 1.7, p < 0.001; Tp-e 82.3 ± 8.7/67.1 ± 5.1, p < 0.001; Tp-e/QTc 0.19 ± 0.01/0.17 ± 0.01, p < 0.001 (respectively)), statistically significant improvements were observed. A statistically significant dose-dependent decline in the magnitude of change in the QTc parameter (19.4/29.6, p = 0.038) was also observed. Conclusions: According to these results, empagliflozin may decrease the risk of potential ventricular arrhythmias

Zależność między ekspresją krążącego mikroRNA a masą lewej komory w objawowej niewydolności serca u chorych z zaburzeniem czynności skurczowej

Background: In recent years, many microRNAs (miRNAs) were shown to be dysregulated in specific tissues playing critical roles in the pathogenesis and progression of heart failure (HF). Left ventricular (LV) mass (LVM) has long been recognised as an important prognostic marker in systolic HF patients. Aim: We hypothesised that circulating miRNAs may be associated with LVM in systolic HF patients. The present study aimed to evaluate the relationship between previously reported and novel dysregulated circulating miRNAs and echocardiographi­cally determined LVM in symptomatic HF patients with LV systolic dysfunction. Methods: Forty-two consecutive patients diagnosed with NYHA II–IV symptomatic systolic HF and a control group consisting of 15 age- and sex-matched healthy volunteers were enrolled. After labelling extracted RNA, poly-A tails were added. RNAs were later hybridised on a GeneChip miRNA 2.0 array. After hybridisation and staining, arrays were scanned to determine miRNA expression levels, and differentially expressed miRNAs were identified. Results: Eighteen miRNAs were found to be upregulated in serum of HF patients, while 11 were demonstrated to be downregulated. When the association between dysregulated miRNAs and echocardiographic findings was investigated, miR-182 (p = 0.04), miR-200a* (p = 0.019), and miR-568 (p = 0.023) were found to be inversely correlated with LVM index (LVMI), while miR-155 (p = 0.019) and miR-595 (p = 0.04) were determined to be positively correlated with LVMI. Conclusions: The results of our study revealed that dysregulated circulating miRNAs were correlated with anatomic changes in LV, in terms of LVMI, in symptomatic HF patients with systolic LV dysfunction.Wstęp: W ostatnich latach wykazano, że zaburzenia ekspresji wielu cząsteczek mikroRNA (miRNA) w określonych tkankach mają podstawowe znaczenie w patogenezie i progresji niewydolności serca (HF). Masę lewej komory (LVM) od dawna uważa się za ważny wskaźnik prognostyczny u chorych ze skurczową HF. Cel: Autorzy niniejszej pracy stworzyli hipotezę, że ekspresja krążących miRNA może się wiązać z LVM u chorych ze skurczową HF. Celem badania była ocena zależności między opisywanymi wcześniej i nowymi miRNA oraz określoną echokardiograficznie LVM u osób z objawową HF i zaburzeniami czynności skurczowej lewej komory. Metody: Do badania włączono 42 kolejnych pacjentów z rozpoznaniem objawowej HF w stopniu II–IV wg NYHA oraz grupę kontrolną złożoną z 15 dopasowanych pod względem wieku i płci zdrowych ochotników. Po oznakowaniu wyeks­trahowanego RNA dodano odcinki poli-A. Następnie przeprowadzono hybrydyzację RNA na matrycy GeneChip miRNA 2.0. Po hybrydyzacji i barwieniu matryce poddano skanowaniu w celu określenia ekspresji miRNA oraz identyfikacji miRNA o różnym stopniu ekspresji. Wyniki: W surowicy chorych z HF stwierdzono zwiększoną ekspresję 18 miRNA i zmniejszoną ekspresję 11 miRNA. Analiza związku między nieprawidłową ekspresją miRNA a wynikami pomiarów echokardiograficznych wykazała ujemną korelację między ekspresją miR-182 (p = 0,04), miR-200a* (p = 0,019) i miR-568 (p = 0,023) a wskaźnikiem LVM (LVMI) oraz dodatnią zależność między ekspresją miR-155 (p = 0,019) i miR-595 (p = 0,04) a LVMI. Wnioski: Wykazano, że nieprawidłowe stężenia krążących miRNA korelowały ze zmianami anatomicznymi lewej komory pod względem LVMI u chorych z objawową HF i zaburzeniami czynności skurczowej lewej komory

The relationship between circulating microRNAs and left ventricular mass in symptomatic heart failure patients with systolic dysfunction

Background: In recent years, many microRNAs (miRNAs) were shown to be dysregulated in specific tissues playing critical roles in the pathogenesis and progression of heart failure (HF). Left ventricular (LV) mass (LVM) has long been recognised as an important prognostic marker in systolic HF patients