2,743 research outputs found
Deep HST V- and I-Band Observations of Two Globular Clusters in the Halo of M31
We present deep (V ~= 27) V- and I-band stellar photometry of G302 and G312,
two globular star clusters in the halo of M31. These data were obtained using
the Hubble Space Telescope's Wide Field/Planetary Camera 2. We find iron
abundances of [Fe/H] = -1.85 +/- 0.12 for G302 and [Fe/H] = -0.56 +/- 0.03 for
G312, consistent with spectroscopic measurements. The color-magnitude diagrams
for each cluster show no evidence for an intermediate-aged population of stars,
or a second parameter effect in the morphology of the horizontal branch. G302
shows no evidence for a color gradient but the inner regions of G312 are bluer
than the outer regions. G312 shows no evidence of ellipticity or an extended
halo of unbound stars. G302 has a projected ellipticity of 0.195 +/- 0.012 with
the projected major axis oriented towards the center of M31. G302 also shows
evidence of an extended asymmetric stellar halo extending to at least twice the
fitted Michie-King tidal radius. The amount of mass beyond the tidal radius of
G302 is consistent with the stellar escape rates which have been predicted by
N-body simulations of globular clusters in the Galactic tidal field.Comment: 29 pages, 21 Postscript figures, uses aaspp4.sty, to be published in
the October 1997 A
Reaction of nitric oxide and its derivatives with sulfites: A possible role in sulfite toxicity
AbstractThe reaction between sulfites and nitric oxide or proposed carriers of nitric oxide (nitrosylated bovine serum albumin and S-nitrosoglutathione) was investigated as a potential source of the adverse effects of sulfites on biological systems. Rapid reaction occurred between sulfites and all of these reagents. Also, the ability of nitric oxide and these carriers of nitric oxide to inhibit platelet aggregation was reversed by low concentrations of sulfites. Counteraction of nitric oxide's ability to function in cell signaling processes may be a major cause of sulfite toxicity
Incremental Prognostic Value of Echocardiographic Strain and Its Association with Mortality in Cancer Patients
Background
Left ventricular global longitudinal systolic strain (GLS) has been shown to be superior to ejection fraction in detecting subclinical dysfunction in patients with cancer and predicting mortality in patients with cardiovascular disease. Cancer-related fatigue is common in the later stages of neoplastic malignancies and may be indicative of nonovert heart failure. The aim of this study was to determine whether reduced strain by echocardiography was associated with all-cause mortality in a cancer cohort.
Methods
In this retrospective study, 120 patients with cancer undergoing or scheduled to undergo chemotherapy and with normal ejection fractions (>50%) underwent assessments of GLS. GLS was derived by averaging all speckle-tracking strain segments of the left ventricle.
Results
Over an average follow-up period of 21.6 ± 13.9 months, 57 of 120 patients died. Univariate predictors of all-cause mortality (P < .10) were Eastern Cooperative Oncology Group performance status, male sex, hematologic malignancy, β-blocker use, and GLS. Multivariate analysis of all significant univariate variables showed that Eastern Cooperative Oncology Group performance status (hazard ratio, 2.12; 95% confidence interval, 1.54–2.92; P < .001), male sex (hazard ratio, 1.93; 95% confidence interval, 1.14–3.27; P = .014), and GLS (hazard ratio, 0.89; 95% confidence interval, 0.81–0.97; P = .012) were significantly and independently associated with mortality. Stepwise analysis of the multivariate associations showed an increase in the global χ2 value after adding GLS (P = .011) to significant clinical variables.
Conclusions
Eastern Cooperative Oncology Group performance status, male sex, and GLS were significantly associated with all-cause mortality in patients with cancer with normal ejection fractions receiving chemotherapy. Adding GLS to significant clinical variables provided incremental prognostic information
Measuring Entangled Qutrits and Their Use for Quantum Bit Commitment
We produce and holographically measure entangled qudits encoded in transverse
spatial modes of single photons. With the novel use of a quantum state
tomography method that only requires two-state superpositions, we achieve the
most complete characterisation of entangled qutrits to date. Ideally, entangled
qutrits provide better security than qubits in quantum bit-commitment: we model
the sensitivity of this to mixture and show experimentally and theoretically
that qutrits with even a small amount of decoherence cannot offer increased
security over qubits.Comment: Paper updated to match published version; 5 pages, 4 figures, images
have been included at slightly lower quality for the archiv
A Young White Dwarf Companion to Pulsar 1620-26: Evidence for Early Planet Formation
The pulsar B1620-26 has two companions, one of stellar mass and one of
planetary mass. We detected the stellar companion using Hubble Space Telescope
observations. The color and magnitude of the stellar companion indicate that it
is an undermassive white dwarf () of age
Myr. This places a constraint on the recent history of this triple system and
supports a scenario in which the current configuration arose through a
dynamical exchange interaction in the cluster core. This implies that planets
may be relatively common in low-metallicity globular clusters and that planet
formation is more widespread and happened earlier than previously believed.Comment: 4 pages, published in Scienc
Prognostic utility of blood pressure-adjusted global and basal systolic longitudinal strain
Assessment of global longitudinal systolic strain (GLS) and longitudinal systolic strain of the basal segments (BLS) has shown prognostic value in cardiac disorders. However, strain is reduced with increased afterload. We assessed the prognostic value of GLS and BLS adjusted for afterload. GLS and BLS were determined in 272 subjects with normal ejection fraction and no known coronary disease, or significant valve disease. Systolic blood pressure (SP) and diastolic blood pressure (DP) obtained at the time of echocardiography were used to adjust GLS and BLS as follows: strain×SP (mmHg)/120 mmHg and strain×DP (mmHg)/80 mmHg. Patients were followed for cardiac events and mortality. The mean age was 53±15 years and 53% had hypertension. There were 19 cardiac events and 70 deaths over a mean follow-up of 26±14 months. Cox analysis showed that left ventricular mass index (P=0.001), BLS (P<0.001), and DP-adjusted BLS (P<0.001) were independent predictors of cardiac events. DP-adjusted BLS added incremental value (P<0.001) to the other two predictors and had an area under the curve of 0.838 for events. DP (P=0.001), age (P=0.001), ACE inhibitor use (P=0.017), and SP-adjusted BLS (P=0.012) were independent predictors of mortality. SP-adjusted BLS added incremental value (P=0.014) to the other independent predictors. In conclusion, DP-adjusted BLS and SP-adjusted BLS were independent predictors of cardiac events and mortality, respectively. Blood pressure-adjusted strain added incremental prognostic value to other predictors of outcome
Entangled Qutrits: Production and Characterisation
We produce and measure entangled qubits and qutrits, two- and three-level quantum systems, realised using transverse spatial modes of the optical field. Photons encoded in these modes are manipulated and analysed by a combination of holograms and single-mode fibres. Using quantum state tomography, we achieve the most complete characterisation of entangled qutrits to date. Ideally, entangled qutrits provide better security than qubits in quantum bit-commitment and coin-flipping protocols: we show that to reach this regime places stringent requirements on the initial state
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