10 research outputs found
Spontaneous Vacuolar Degeneration of the Thyroid Follicular Epithelium in Cynomolgus Monkeys
Vacuolar degeneration of the thyroid follicular epithelium was observed in two untreated
female cynomolgus monkeys assigned to control groups. In light microscopy, large vacuoles
containing a homogenous substance occupied the basal region of the epithelium, and the
nuclei had shifted toward the apical region. The vacuoles showed negative reactions to PAS
and thyroglobulin. Electron microscopic observation revealed dilatation of the rough
endoplasmic reticulum corresponding to the vacuoles. The plasma TSH, T3 and T4 levels
determined for the samples kept frozen were within the normal ranges, suggesting that the
thyroid function was kept intact
Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer
Division of Medical Oncology and Surgical Oncolog