Total Synthesis of (+)-Vicenin‑2

The bis-<i>C</i>-glucosyl flavonoid vicenin-2 (<b>1</b>) has been synthesized by exploiting bis-<i>C</i>-glycosylation of 1,3,5-trifluorobenzene and aromatic nucleophilic substitution to transform fluorine atoms to oxygen functions in excellent yield