First Quarter Hanford Seismic Report for Fiscal Year 2001

Hanford Seismic Monitoring provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network (HSN) for the U.S. Department of Energy and its contractors. Hanford Seismic Monitoring also locates and identifies sources of seismic activity and monitors changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, Natural Phenomena Hazards assessments, and engineering design and construction. In addition, the seismic monitoring organization works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The HSN and the Eastern Washington Regional Network (EWRN) consist of 41 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Monitoring staff. For the HSN, there were 477 triggers during the first quarter of fiscal year (FY ) 2001. The peak of the activity occurred over December 12th, 13th, and 14th when 35 events occurred. No earthquakes triggered the Hanford Strong Motion Accelerometers during the first quarter of FY 2001

Second and Third Quarter Hanford Seismic Report for Fiscal Year 2001

This report describes the seismic activity on the Hanford Site during the 2nd and 3rd quarters of FY0

Third Quater Seismic Report for Fiscal Year 2007

The Hanford Seismic Assessment Program (HSAP) provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network for the U.S. Department of Energy and its contractors. The Hanford Seismic Assessment Team locates and identifies sources of seismic activity and monitors changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, Natural Phenomena Hazards assessments, and engineering design and construction. In addition, the seismic monitoring organization works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The Hanford Seismic Network and the Eastern Washington Regional Network consist of 41 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Assessment Team. For the Hanford Seismic Network, 16 local earthquakes were recorded during the third quarter of fiscal year 2007. The largest event (magnitude 2.0) occurred on April 16, 2007 and was located 4 km southwest of the 400 Area in the Columbia River basalts at a depth of approximately 3 km. Stratigraphically, 7 earthquakes occurred in the Columbia River basalts (approximately 0-5 km depth), 1 earthquake in the pre-basalt sediments (approximately 5-10 km depth), and 8 earthquakes in the crystalline basement (approximately 10-25 km depth). Geographically, 8 earthquakes occurred in swarm areas, and 8 earthquakes were classified as random events. The Hanford SMA network was triggered on the 300 Area and the 400 Area SMA by the 2.0 Mc seismic event that occurred on April 16, 2007. The maximum vertical acceleration was 0.07 % g and the maximum horizontal acceleration was 0.05% g at the 300 Area SMA, 13.5 km from the event. At the 400 Area SMA, only 5.2 km from the event, the maximum vertical acceleration was 0.25 % g and the maximum horizontal acceleration was 0.23% g. These are the first recordings of a small local earthquake on the SMA network. The reportable action level of 2% g for Hanford facilities is approximately 8 times larger than the peak accelerations observed at the 400 Area and no action was required

Fiscal Year 2005

This reports on earthquakes recorded in the Hanford Seismic Network during Fiscal Year 2005

First Quarter Seismic Report for Fiscal Year 2006

This report describes the earthquake data collected from October 2005 to December 2005 from the Hanford Seismic Networ

Fiscal Year 2006

This report summarizes the earthquake activity at the Hanford Site a vicinty that occurred during FY 200

Fiscal Year 2007

This annual report documents the locations, magnitudes, and geologic interpretations of earthquakes recorded for the Hanford monitoring region of south-central Washington in fiscal year 2007 (October 2006 through September 2007). The report provides summaries of seismic events recorded during the first three quarters of fiscal year 2007 and contains a more comprehensive discussion of seismic events for the fourth quarter of the fiscal year

Third Quarter Hanford Seismic Report for Fiscal Year 2008

The Hanford Seismic Assessment Program (HSAP) provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network for the U.S. Department of Energy and its contractors. The Hanford Seismic Assessment Team locates and identifies sources of seismic activity and monitors changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, natural phenomena hazards assessments, and engineering design and construction. In addition, the seismic monitoring organization works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The Hanford Seismic Network and the Eastern Washington Regional Network consist of 44 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Assessment Team. For the Hanford Seismic Network, fourteen local earthquakes were recorded during the third quarter of fiscal year 2008. The largest event recorded by the network during the third quarter (May 18, 2008 - magnitude 3.7 Mc) was located approximately 17 km east of Prosser at a depth of 20.5 km. With regard to the depth distribution, five earthquakes occurred at shallow depths (less than 4 km, most likely in the Columbia River basalts), six earthquakes at intermediate depths (between 4 and 9 km, most likely in the pre-basalt sediments), and three earthquakes were located at depths greater than 9 km, within the crystalline basement. Geographically, eight earthquakes occurred in swarm areas and six earthquakes were classified as random events. The largest event recorded by the network during the third quarter occurred on May 18 (magnitude 3.7 Mc) and was located approximately 17 km east of Prosser at a depth of 20.5 km. This earthquake was the highest magnitude event recorded in the 46-47 N. latitude / 119-120 W. longitude sector since 1975. The May 18 event, not reported as being felt on the Hanford site or causing any damage, was communicated to the PNNL Operations Center per HSAP communications procedures. The event is not considered to be significant with regard to site safety and not unprecedented given the site’s seismic history. The Hanford strong motion accelerometer (SMA) stations at the 200 East Area, 300 Area, and the 400 Area were triggered by the May 18 event. The reportable action level of 2% g for Hanford facilities is approximately 12 times larger than the peak acceleration (0.17%) observed at the 300 Area SMA station and no action was required

Fiscal Year 2008

The Hanford Seismic Assessment Program (HSAP) provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network for the U.S. Department of Energy and its contractors. The HSAP is responsible for locating and identifying sources of seismic activity and monitoring changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, natural phenomena hazards assessments, and engineering design and construction. In addition, the HSAP works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The Hanford Seismic Network and the Eastern Washington Regional Network consist of 44 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Assessment Team. During fiscal year 2008, the Hanford Seismic Network recorded 1431 triggers on the seismometer system, which included 112 seismic events in the southeast Washington area and an additional 422 regional and teleseismic events. There were 74 events determined to be local earthquakes relevant to the Hanford Site. The highest-magnitude event (3.7 Mc) occurred on May 18, 2008, and was located approximately 17 km east of Prosser at a depth of 20.5 km. With regard to the depth distribution, 13 earthquakes were located at shallow depths (less than 4 km, most likely in the Columbia River basalts), 45 earthquakes were located at intermediate depths (between 4 and 9 km, most likely in the pre-basalt sediments), and 16 earthquakes were located at depths greater than 9 km, within the crystalline basement. Geographically, 54 earthquakes were located in swarm areas and 20 earthquakes were classified as random events. The May 18 earthquake was the highest magnitude event recorded since 1975 in the vicinity of the Hanford Site (between 46 degrees and 47 degrees north latitude and 119 degrees and 120 degrees west longitude). The event was not reported as being felt on the Hanford Site or causing any damage and was communicated to the Pacific Northwest National Laboratory Operations Center per HSAP communi¬cations procedures. The event is not considered to be significant with regard to site safety and not unprecedented given the site’s seismic history. The Hanford strong motion accelerometer (SMA) stations at the 200 East Area, 300 Area, and 400 Area were triggered by the May 18 event. The maximum acceleration recorded at the SMA stations (0.17% at the 300 Area) was 12 times smaller than the reportable action level (2% g) for Hanford Site facilities

Cationic Host Defence Peptides:Potential as Antiviral Therapeutics

There is a pressing need to develop new antiviral treatments; of the 60 drugs currently available, half are aimed at HIV-1 and the remainder target only a further six viruses. This demand has led to the emergence of possible peptide therapies, with 15 currently in clinical trials. Advancements in understanding the antiviral potential of naturally occurring host defence peptides highlights the potential of a whole new class of molecules to be considered as antiviral therapeutics. Cationic host defence peptides, such as defensins and cathelicidins, are important components of innate immunity with antimicrobial and immunomodulatory capabilities. In recent years they have also been shown to be natural, broad-spectrum antivirals against both enveloped and non-enveloped viruses, including HIV-1, influenza virus, respiratory syncytial virus and herpes simplex virus. Here we review the antiviral properties of several families of these host peptides and their potential to inform the design of novel therapeutics