2,800 research outputs found
High-speed roll-to-roll manufacturing of graphene using a concentric tube CVD reactor
We present the design of a concentric tube (CT) reactor for roll-to-roll chemical vapor deposition (CVD) on flexible substrates, and its application to continuous production of graphene on copper foil. In the CTCVD reactor, the thin foil substrate is helically wrapped around the inner tube, and translates through the gap between the concentric tubes. We use a bench-scale prototype machine to synthesize graphene on copper substrates at translation speeds varying from 25 mm/min to 500 mm/min, and investigate the influence of process parameters on the uniformity and coverage of graphene on a continuously moving foil. At lower speeds, high-quality monolayer graphene is formed; at higher speeds, rapid nucleation of small graphene domains is observed, yet coalescence is prevented by the limited residence time in the CTCVD system. We show that a smooth isothermal transition between the reducing and carbon-containing atmospheres, enabled by injection of the carbon feedstock via radial holes in the inner tube, is essential to high-quality roll-to-roll graphene CVD. We discuss how the foil quality and microstructure limit the uniformity of graphene over macroscopic dimensions. We conclude by discussing means of scaling and reconfiguring the CTCVD design based on general requirements for 2-D materials manufacturing.National Science Foundation (U.S.). Science, Engineering, and Education for Sustainability (Postdoctoral Fellowship Award 1415129
Spatial Mapping of Powder Layer Density for Metal Additive Manufacturing via X-ray Microscopy
Uniform powder spreading is a requisite for creating consistent, high-quality
components via powder bed additive manufacturing (AM), wherein layer density
and uniformity are complex functions of powder characteristics, spreading
kinematics, and mechanical boundary conditions. High spatial variation in
particle packing density, driven by the stochastic nature of the spreading
process, impedes optical interrogation of these layer attributes. Thus, we
present transmission X-ray imaging as a method for directly mapping the
effective depth of powder layers at process-relevant scale and resolution.
Specifically, we study layers of nominal 50-250 micrometer thickness, created
by spreading a selection of commercially obtained Ti-6Al-4V, 316 SS, and
Al-10Si-Mg powders into precision-depth templates. We find that powder layer
packing fraction may be predicted from a combination of the relative thickness
of the layer as compared to mean particle size, and flowability assessed by
macroscale powder angle of repose. Power spectral density analysis is
introduced as a tool for quantification of defect severity as a function of
morphology, and enables separate consideration of layer uniformity and
sparsity. Finally, spreading is studied using multi-layer templates, providing
insight into how particles interact with both previously deposited material and
abrupt changes in boundary condition. Experimental results are additionally
compared to a purpose-built discrete element method (DEM) powder spreading
simulation framework, clarifying the competing role of adhesive and
gravitational forces in layer uniformity and density, as well as particle
motion within the powder bed during spreading
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs
The human protein interaction network will offer global insights into the molecular organization of cells and provide a framework for modeling human disease, but the network's large scale demands new approaches. We report a set of 7000 physical associations among human proteins inferred from indirect evidence: the comparison of human mRNA co-expression patterns with those of orthologous genes in five other eukaryotes, which we demonstrate identifies proteins in the same physical complexes. To evaluate the accuracy of the predicted physical associations, we apply quantitative mass spectrometry shotgun proteomics to measure elution profiles of 3013 human proteins during native biochemical fractionation, demonstrating systematically that putative interaction partners tend to co-sediment. We further validate uncharacterized proteins implicated by the associations in ribosome biogenesis, including WBSCR20C, associated with Williams–Beuren syndrome. This meta-analysis therefore exploits non-protein-based data, but successfully predicts associations, including 5589 novel human physical protein associations, with measured accuracies of 54±10%, comparable to direct large-scale interaction assays. The new associations' derivation from conserved in vivo phenomena argues strongly for their biological relevance
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Enhancement of microphase ordering and mechanical properties of supramolecular hydrogen-bonded polyurethane networks
The improvement of the mechanical properties of supramolecular polymer networks is currently receiving significant interest both within academic and industrial circles in order to enable the application of these desirable stimuli-responsive materials in real world situations. In this study, structural units within phase separated supramolecular polyurethane (SPU) networks have been changed to assess the role of the hard segment composition on the mechanical characteristics of the resultant materials. Notably, increasing the degrees of conformational freedom within the hard segment component of a SPU was found to improve the phase separation and as a consequence also increase the storage modulus of the polymer network. Specifically, replacing 4,4′-methylene diphenyl diisocyanate with 4,4’-dibenzyl diisocyanate within a SPU improved the packing efficiency of the isocyanate derived hard segments and improved the physical properties of the supramolecular polymer network. This study utilised a combination of SAXS, WAXS and AFM analysis to assess the degree of crystallinity within the hard segment component of the polymer network whilst rheological analysis was used to establish the mechanical characteristics of the polymers
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