16 research outputs found
Relationship between maternal omentin-1 levels and clinical features.
<p>Scatter plots depicting the relationship between log maternal omentin 1 versus (<b>A</b>) maternal BMI at 12 weeks, (<b>B</b>) fasting OGTT at 28 weeks, (<b>C</b>) log maternal HOMA-IR at delivery and (<b>D</b>) fetal ponderal index.</p
Localisation of omentin-1 in human placenta.
<p>(<b>A</b>) Immunohistochemical localisation of omentin-1 protein in human placenta. Omentin-1 staining was mainly contained in syncytiotrophoblasts (sy) and endothelial cells (ec). Magnification 400Γ. (<b>B</b>) No specific staining is seen in the negative control for placenta. Magnification 250Γ.</p
Effect of obesity on omentin-1 expression and release from placenta and omental adipose tissue.
<p>Omentin-1 (<b>A</b>) gene expression and (<b>B</b>) release from human placenta and omental adipose tissue obtained from NGT non-obese (nβ=β14 for placenta andβ=β13 for omental) and obese (nβ=β8) pregnant women. Each bar represents the mean Β± SEM. *<i>P</i><0.05 vs. non-obese placenta; <sup>β </sup><i>P</i><0.05 vs. non-obese adipose tissue.</p
Effect of pregnancy on circulating omentin-1 levels.
<p>Omentin-1 levels in women at 11 and 28 weeks gestation and 7 weeks postpartum (non pregnant). Each bar represents the mean Β± SEM (nβ=β11 per group). *<i>P</i><0.05 vs. 11 weeks gestation.</p
Effect of GDM on omentin-1 expression and release from placenta and omental adipose tissue.
<p>Omentin-1 (<b>A</b>) gene expression and (<b>B</b>) release from human placenta and omental adipose tissue from NGT (nβ=β22 for placenta; nβ=β21 for omental and subcutaneous adipose tissue) and GDM (nβ=β22 for placenta; nβ=β20 for omental adipose tissue; nβ=β19 for subcutaneous adipose tissue) pregnant women. Each bar represents the mean Β± SEM.</p
Plasma study: Characteristics of the study group.
<p>Values represent mean Β± SEM.</p>*<p><i>P</i><0.05 vs. NGT non-obese;</p>**<p><i>P</i><0.05 vs. GDM non-obese.</p>Β§<p>Rohrer's ponderal index is defined as birthweight (g)/birth length<sup>3</sup> (cm<sup>3</sup>) Γ100 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042943#pone.0042943-Lehingue1" target="_blank">[39]</a>.</p>β‘<p>OGTT β oral glucose tolerance test at βΌ28 weeks gestation.</p
Spearman's rank order correlation analysis.
<p>Spearman's rank order correlation analysis.</p
The effect of sexual intercourse and vaginal microbiology status on VDBP concentration.
<p>(A) Unprotected sexual intercourse within 48 h of CVF collection did not affect the VDBP concentration in women who delivered either term (<i>P</i>β=β0.237) or preterm (<i>P</i>β=β0.406, 2-way ANOVA). (B) The microbiology status of women with subsequent preterm or term labour did not affect the VDBP concentration. Within each labour group, VDBP was not significantly different between women with normal vaginal flora, Group B Streptococcus (GBS) colonisation, <i>Candida</i> spp. colonisation, <i>Ureaplasma</i> spp. colonisation, and women with mixed colonisation (Term: <i>P</i>β=β0.478, Preterm: <i>P</i>β=β0.557; 2-way ANOVA). The box and whisker plots represent the median and interquartile range with the 5<sup>th</sup> and 95<sup>th</sup> centile range. Outliers are represented by open circles.</p
The VDBP concentration in the CVF significantly increased with advancing gestational age.
<p>The * indicates significance in the VDBP concentration in gestational groups β€30β31 weeks' compared with CVF samples collected β₯36 weeks' gestation. The β indicates significance in VDBP concentration between samples collected at 36 and 37 weeks' gestation compared with samples collected at 40 and 41 weeks' gestation. Statistical significance was defined as <i>P</i><0.05 (2-way ANOVA). The box and whisker plots represent the median and interquartile range with the 5<sup>th</sup> and 95<sup>th</sup> centile range. Outliers are represented by open circles.</p