Achieving the Potential of Health Care Performance Measures: Timely Analysis of Immediate Health Policy issues

The United States is on the cusp of a new era, with greater demand for performance information, greater data availability, and a greater willingness to integrate performance information into public policy. This era has immense promise to deliver a learning health care system that encourages collaborative improvements in systems-based care, improves accountability, helps consumers make important choices, and improves quality at an acceptable cost. However, to curtail the possibility of unintended adverse consequences, it is important that we invest in developing sound measures, understand quality measures' strengths and limitations, study the science of quality measurement, and reduce inaccurate inferences about provider performance

A new, temporarily confined population in the polar cap during the August 27, 1996 geomagnetic field distortion period

On August 27, 1996, a two-hour energetic heavy ion event (∼1 MeV) was detected at 8:25 UT at apogee (∼9 Re and an invariant latitude of ∼80°), by the Charge and Mass Magnetospheric Ion Composition Experiment onboard POLAR. The event, with a maximum spin averaged peak flux of ∼150 particles/(cm²-sr-s-MeV), showed three local peaks corresponding to three localized regions; the ion pitch angle distributions in the three regions were different from an isotropic distribution and different from each other. No comparable flux was observed by the WIND spacecraft. The appearance of lower energy He++ and O \u3e +2 during the event period indicates a solar source for these particles. From region 1 to 2 to 3, the helium energy spectra softened. A distorted magnetic field with three local minima corresponding to the three He peak fluxes was also observed by POLAR. A possible explanation is that the energetic He ions were energized from lower energy helium by a local acceleration mechanism that preferred smaller rigidity ions in the high altitude polar cusp region

Metabolic Effects of Avocado/Soy Unsaponifiables on Articular Chondrocytes

Avocado/soy unsaponifiable (ASU) components are reported to have a chondroprotective effect by virtue of anti-inflammatory and proanabolic effects on articular chondrocytes. The identity of the active component(s) remains unknown. In general, sterols, the major component of unsaponifiable plant material have been demonstrated to be anti-inflammatory in vitro and in animal models. These studies were designed to clarify whether the sterol content of ASU preparations were the primary contributors to biological activity in articular chondrocytes. ASU samples were analyzed by high pressure liquid chromatography (HPLC) and GC mass spectrometry. The sterol content was normalized between diverse samples prior to in vitro testing on bovine chondrocytes. Anabolic activity was monitored by uptake of 35-sulfate into proteoglycans and quantitation of labeled hydroxyproline and proline content after incubation with labeled proline. Anti-inflammatory activity was assayed by measuring reduction of interleukin-1 (IL-1)-induced synthesis of PGE2 and metalloproteases and release of label from tissue prelabeled with S-35.All ASU samples exerted a similar time-dependent up-regulation of 35-sulfate uptake in bovine cells reaching a maximum of greater than 100% after 72 h at sterol doses of 1–10 μg/ml. Non-collagenous protein (NCP) and collagen synthesis were similarly up-regulated. All ASU were equally effective in dose dependently inhibiting IL-1-induced MMP-3 activity (23–37%), labeled sulfate release (15–23%) and PGE2 synthesis (45–58%). Up-regulation of glycosaminoglycan and collagen synthesis and reduction of IL-1 effects in cartilage are consistent with chondroprotective activity. The similarity of activity of ASU from diverse sources when tested at equal sterol levels suggests sterols are important for biologic effects in articular chondrocytes

Nitrogen Fertilizer, Cropping Systems, and Iowa Groundwater

Summary presentation of research conducted over a 5 year period to determine which cropping systems best reduce nitrate leaching. Initial data was collected on nitrate concentration from individual wells in the Sioux Center, Iowa area which led to connections with the Iowa Department of Natural Resources Source Water Protection Program. A community group was then formed comprised of city representatives, Dordt College faculty, local farmers, Source Water Protection Program staff, and others. The group applied for and received a Leopold Center for Sustainable Agriculture grant to fund field experiments to identify cropping systems that retain nitrate and are workable for producers. Five different cropping systems were tested over a five year period. These included continuous corn, continuous grass hay, oat/alfalfa/corn, oat/red clover/corn, and soybean/winter wheat/corn. Results of residual nitrate nitrogen levels for each of the crop rotations is presented along with preliminary economic summaries

Studies on Old World Bluestems

The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Germination Characteristics of Some Accessions of 'Bothriochloa ischaemum' (L.) Keng

The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311