Massive spontaneous corpus callosal hemorrhage with intraventricular extension

Spontaneous hemorrhage into the corpus callosum with intraventricular extension is uncommon. In the present article we describe a case 60 year female who had massive hemorrhage along the corpus callosum involving genu, body of corpus callosum and extending on ventral as well as dorsal aspect of the corpus callosum with intraventricular extension and areas of hypodensities in the body of the corpus callosum and adjacent cerebral cortex. In this case the subarachnoid and corpus callosal hemorrhage probably resulted from the ruptured aneurysms of the anterior cerebral artery

Developing a traumatic brain injury registry: lessons learned from difficulties

Aim: The aim of present article is to share our experiences and lessons learned from a pilot study which was conducted to collect data to serve as a model in establishing a multi-center registry on traumatic brain injury patients.Methods: The present study was conducted from December 2013 to June 2014 in the Department of Neurosurgery and Department of Accident and Emergency Medicine. All patients with the diagnosis of traumatic brain injury (as per the criteria laid by International Classification of Disease injury codes ICD 10) were enrolled in the study. Variables were identified as per the international norms and the data points were selected which included demographic details, pre-hospital characteristics, clinical details in emergency room, injury details, course during hospital stay, treatment and disposition. The data were categorized into master data, data related to pre-hospital events including pre-hospital care, data related to emergency room care offered in the emergency department, data related to hospital stay and patient course, outcome and follow up.Results: A total of 231 patients were admitted with the diagnosis of traumatic brain injury. There were 79.1% male and 20.5% female patients. Mean age was 37.19 years (SD±17.02 years, range 4-87 years). Mean hospital stay was 3.66 days (SD±4.46 days, range-1-21 days). Data were collected daily for all the admitted patients on previous day fulfilling the inclusion criteria. The Proforma was easy to comprehend and it was easy to fill.Conclusion: We found that a well-designed Proforma based under supervision data collection in a relatively low volume trauma center. We found that a well-designed Proforma based under supervision data collection in a relatively low volume trauma center and at regular intervals can be cost-effective which can be managed by personnel with basic training

Structural, Hirshfeld surface and three-dimensional interaction-energy studies of 1,3,5-triethyl 2-amino-3,5-dicyano-4,6-bis(4-fluorophenyl)cyclohex-1-ene-1,3,5-tricarboxylate

In the title compound, C29H27F2N3O6, which crystallizes in the monoclinic space group P21/c, the cyclohexenone ring is puckered and adopts an envelope conformation. The crystal structure features various intermolecular interactions, such as N—H...O, C—H...N and C—H...O. These interactions were investigated using Hirshfeld surface analysis and the three-dimensional interaction energies were calculated using the B3LYP/6–31 G(d,p) energy density model

Cirsoid aneurysm of scalp: Value of multidetector CT scan in pre-operative evaluation

Cirsoid aneurysm of scalp is a rare arteriovenous malformation (AVM) of external carotid branches and scalp veins. This malformation of scalp is also synonymously called as plexiform angioma, aneurysma racesomsum, and aneurysm cirsoide, aneurysma serpentinum. This AVM can be congenital or acquired; a congenital form will be present at birth, however, becomes overt only after puberty. Superficial temporal artery is the feeder in approximately 70-80% of the cases, followed by occipital and supraorbital artery. Multidetector computed tomography angiography reconstructed images can provide excellent detail of the feeders, draining veins and their soft tissue relations. Volume rendering data sets in computer workstations we can actually perform virtual dissection layers of the lesion for operative planning. Well planned surgical excision can have least surgical recurrence rates and complications

Pharmacognostic and Analytical Profile of Leaves of Erythroxylum Moonii Hochr. – An Ethno-Medicinal Plant

Erythroxylum moonii Hochr. is a shrub or small tree in family Erythroxylaceae and folklore claims report the use of its leaves in the treatment of helminthiasis. Aim: Hence, present study aims to evaluate the pharmacognostic and analytical characters including HPTLC of its leaves. Methods: E. moonii fresh and powdered leaves were explored for the macroscopic and microscopic features along with their physico-chemical, phytochemical properties and HPTLC following standard procedures. Results: The leaf of E. moonii is simple, alternate, petiolate, stipulate, elliptic and lanceolate with obtusely caudate-acuminate apex, acute base and entire margins. Fresh leaf is light green, slight astringent with characteristic odour and smooth texture. Powdered dry leaves were light green, slight astringent with aromatic odour and coarse, fibrous texture. Microscopic evaluation revealed the presence of simple, bilobed and stellate trichomes (with and without lignification), rosette, rhomboidal, prismatic and cluster crystals, paracytic stomata and starch grains as key characteristics both in fresh leaves and powdered leaves. Obtained values for loss on drying, total ash, acid insoluble ash, pH, water and methanol soluble extractive were 10.44±0.31%, 2.2±0.67%, 0.93±0.06%, 5, 7.63±0.57% and 6.44±0.38% respectively. Qualitative phytochemical analysis suggested the presence of carbohydrates, steroids, glycosides, saponins, alkaloids, tannins and flavonoids in the test sample. HPTLC study revealed 17 and 11 peaks at short (254nm) and long (366nm) ultraviolet consecutively. Conclusion: Obtained results can be used to establish pharmacognostic and analytical standards of leaves of E. moonii which can serve as an important source to determine the quality, purity and strength of the powdered drug.&nbsp