The Rehabilitation of Terminal 2 – A Case History

The Port of Portland, Oregon recently completed the rehabilitation of the downstream portion of Terminal 2. The project included the placement of more than 1 million cy of dredged hydraulic sand fill and the construction of a 1,400-ft-long pile-supported wharf. Up to 60 ft of sand fill was placed over soft, submerged sediments. The silt along the toe of the slope was removed prior to placing the fill. No shear failures or mudwaves were detected during filling. The fill induced settlements of up to 63 in., which agreed well with the predicted maximum settlement of about 60 in. Underwater sand fill slopes were placed at about 2.5H: 1V and subsequently trimmed to 2.25H: 1V. The slope was subsequently densified and steepened to 1.75H: 1V with fragmental quarry rock. After slope construction, 840 vertical, 24-in. octagonal prestressed concrete piles were driven for the wharf

The Networked Common Goods Game

We introduce a new class of games called the networked common goods game (NCGG), which generalizes the well-known common goods game. We focus on a fairly general subclass of the game where each agent's utility functions are the same across all goods the agent is entitled to and satisfy certain natural properties (diminishing return and smoothness). We give a comprehensive set of technical results listed as follows. * We show the optimization problem faced by a single agent can be solved efficiently in this subclass. The discrete version of the problem is however NP-hard but admits an fully polynomial time approximation scheme (FPTAS). * We show uniqueness results of pure strategy Nash equilibrium of NCGG, and that the equilibrium is fully characterized by the structure of the network and independent of the choices and combinations of agent utility functions. * We show NCGG is a potential game, and give an implementation of best/better response Nash dynamics that lead to fast convergence to an $\epsilon$-approximate pure strategy Nash equilibrium. * Lastly, we show the price of anarchy of NCGG can be as large as $\Omega(n^{1-\epsilon})$ (for any $\epsilon>0$), which means selfish behavior in NCGG can lead to extremely inefficient social outcomes

Gravitational Lensing Magnification and Time Delay Statistics for Distant Supernovae

Strong gravitational lensing of distant supernovae (SNe), particularly Type Ia's, has some exploitable properties not available when other sorts of cosmologically distant sources are lensed. One such property is that the ``standard candle'' nature of the SN at peak brightness allows a direct determination of the lensing magnification factor for each well observed image. Another is that the duration of an SN event is of the same order as the differential time delays between the various lens images. The comparable time scales of the photometric event and the time delay invite a variety of applications, including high precision measurements of the delay and the targeting of especially interesting phases of the explosion for intensive observation when they appear in trailing images. As an initial exploration of these possibilities we present calculations of SN lensing statistics in a ``concordance cosmology''. We emphasize magnification and time delay effects. Plausible SN surveys, such as the proposed SNAP space mission, would discover several to some tens of strongly lensed SNe Ia per year, and at least a few of these will be at redshifts well beyond those that would be accessible via unlensed events. The total number of such anomalously high redshift SNe Ia will be a useful test of high redshift star formation models. SN surveys of finite duration will, of course, miss the appearance of some images; we quantify this selection bias. Finally, we investigate how well the appearance of trailing images can be predicted based on various amounts of available information on the lensing event. Knowledge of the magnification factor for the leading image makes it possible to predict the appearance of a trailing image relatively accurately if the lens redshift is also known. (Abridged)Comment: 11 pages, 9 figures, emulateapj5, accepted for publication in Ap

A Raman spectroscopic and computational study of new aromatic pyrimidine-based halogen bond acceptors

© 2019 by the authors. Two new aromatic pyrimidine-based derivatives designed specifically for halogen bond directed self-assembly are investigated through a combination of high-resolution Raman spectroscopy, X-ray crystallography, and computational quantum chemistry. The vibrational frequencies of these new molecular building blocks, pyrimidine capped with furan (PrmF) and thiophene (PrmT), are compared to those previously assigned for pyrimidine (Prm). The modifications affect only a select few of the normal modes of Prm, most noticeably its signature ring breathing mode, ν1. Structural analyses afforded by X-ray crystallography, and computed interaction energies from density functional theory computations indicate that, although weak hydrogen bonding (C-H...O or C-H...N interactions) is present in these pyrimidine-based solid-state co-crystals, halogen bonding and π-stacking interactions play more dominant roles in driving their molecular-assembly

Reynolds number influences in aeronautics

Reynolds number, a measure of the ratio of inertia to viscous forces, is a fundamental similarity parameter for fluid flows and therefore, would be expected to have a major influence in aerodynamics and aeronautics. Reynolds number influences are generally large, but monatomic, for attached laminar (continuum) flow; however, laminar flows are easily separated, inducing even stronger, non-monatomic, Reynolds number sensitivities. Probably the strongest Reynolds number influences occur in connection with transitional flow behavior. Transition can take place over a tremendous Reynolds number range, from the order of 20 x 10(exp 3) for 2-D free shear layers up to the order of 100 x 10(exp 6) for hypersonic boundary layers. This variability in transition behavior is especially important for complex configurations where various vehicle and flow field elements can undergo transition at various Reynolds numbers, causing often surprising changes in aerodynamics characteristics over wide ranges in Reynolds number. This is further compounded by the vast parameterization associated with transition, in that any parameter which influences mean viscous flow development (e.g., pressure gradient, flow curvature, wall temperature, Mach number, sweep, roughness, flow chemistry, shock interactions, etc.), and incident disturbance fields (acoustics, vorticity, particulates, temperature spottiness, even electro static discharges) can alter transition locations to first order. The usual method of dealing with the transition problem is to trip the flow in the generally lower Reynolds number wind tunnel to simulate the flight turbulent behavior. However, this is not wholly satisfactory as it results in incorrectly scaled viscous region thicknesses and cannot be utilized at all for applications such as turbine blades and helicopter rotors, nacelles, leading edge and nose regions, and High Altitude Long Endurance and hypersonic airbreathers where the transitional flow is an innately critical portion of the problem

Insulin versus oral agents in the management of Cystic Fibrosis Related Diabetes: a case based study

BACKGROUND: Insulin is the recommend therapeutic agent of choice for the management of Cystic Fibrosis Related Diabetes (CFRD), despite only sub-optimal reductions in glycemic control and increased morbidity and mortality reported by centers using this agent. The newer insulin sensitizing agents demonstrated to have anti-inflammatory mechanisms may provide an alternative management option for CFRD. METHODS: A prospective case based therapeutic comparison between insulin, sulfonylurea, metformin and thiazolidinedione was observed over one decade with 20 CFRD patients diagnosed using American Diabetes Association guideline standards. Patients entering the study elected treatment based on risk and benefit information provided for treatment options. Patients receiving organ transplant or requiring combination diabetic medications were excluded from the study. RESULTS: No statistical advantage was achieved regarding overall glycemic control for oral agents over insulin. Additional outcome measures including changes in weight, liver function testing and FEV(1 )were not statistically significant. CONCLUSION: Insulin alone may not be the only therapeutic option in managing CFRD. Oral hypoglycemic agents were equally effective in treating CFRD and may provide an alternative class of agents for patients reluctant in using insulin

The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/β-catenin asymmetry pathway

AbstractDishevelleds are modular proteins that lie at the crossroads of divergent Wnt signaling pathways. The DIX domain of dishevelleds modulates a β-catenin destruction complex, and thereby mediates cell fate decisions through differential activation of Tcf transcription factors. The DEP domain of dishevelleds mediates planar polarity of cells within a sheet through regulation of actin modulators. In Caenorhabditis elegans asymmetric cell fate decisions are regulated by asymmetric localization of signaling components in a pathway termed the Wnt/β-catenin asymmetry pathway. Which domain(s) of Disheveled regulate this pathway is unknown. We show that C. elegans embryos from dsh-2(or302) mutant mothers fail to successfully undergo morphogenesis, but transgenes containing either the DIX or the DEP domain of DSH-2 are sufficient to rescue the mutant phenotype. Embryos lacking zygotic function of SYS-1/β-catenin, WRM-1/β-catenin, or POP-1/Tcf show defects similar to dsh-2 mutants, including a loss of asymmetry in some cell fate decisions. Removal of two dishevelleds (dsh-2 and mig-5) leads to a global loss of POP-1 asymmetry, which can be rescued by addition of transgenes containing either the DIX or DEP domain of DSH-2. These results indicate that either the DIX or DEP domain of DSH-2 is capable of activating the Wnt/β-catenin asymmetry pathway and regulating anterior–posterior fate decisions required for proper morphogenesis

Mergers and Target Transparency

We empirically investigate the hypothesis that the less transparent (more difficult to value) the target’s assets are the more likely it is that the acquiring firm can obtain higher short- and long-term returns. We analyze a sample of 1,538 friendly acquisitions partitioned in two separate dimensions: acquisitions of public versus private firms, and acquisitions of a firm’s assets versus acquisitions of a firm’s assets and its management. Using a sample of (nondiversifying) real estate transactions with a public REIT as the acquirer, we find that acquisitions of public firms have insignificant short-term abnormal returns. Acquisitions of private targets have positive and significant short-term abnormal returns. The acquirer’s abnormal returns are higher in both cases when the transactions involve acquisition of the target firm’s management. We find parallel results when analyzing the acquirer’s Q over the merger year and the three following years. Our conclusions are robust to the type of financing (cash, stock, or a combination) used in the acquisition

High Redshift Supernova Rates

We use a sample of 42 supernovae detected with the Advanced Camera for Surveys on-board the Hubble Space Telescope as part of the Great Observatories Origins Deep Survey to measure the rate of core collapse supernovae to z~0.7 and type Ia supernovae to z~1.6. This significantly increases the redshift range where supernova rates have been estimated from observations. The rate of core collapse supernovae can be used as an independent probe of the cosmic star formation rate. Based on the observations of 17 core collapse supernovae, we measure an increase in the core collapse supernova rate by a factor of 1.6 in the range 0.3<z<0.7, and an overall increase by a factor of 7 to z~0.7 in comparison to the local core collapse supernova rate. The increase in the rate in this redshift range in consistent with recent measurements of the star formation rate derived from UV-luminosity densities and IR datasets. Based on 25 type Ia supernovae, we find a SN Ia rate that is a factor 3-5 higher at z~1 compared to earlier estimates at lower redshifts (z<0.5), implying that the type Ia supernova rate traces a higher star formation rate at redshifts z>1 compared to low redshift. At higher redshift (z>1), we find a suggested decrease in the type Ia rate with redshift. This evolution of the Ia rate with redshift is consistent with a type Ia progenitor model where there is a substantial delay between the formation of the progenitor star and the explosion of the supernova. Assuming that the type Ia progenitor stars have initial main sequence masses 3-8 M_Sun, we find that 5-7% of the available progenitors explode as type Ia supernovae.Comment: 16 pages, 3 figures, accepted for publication in the Astrophysical Journa