A hydraulic analysis of shock wave generation mechanism on flat spillway chutes through physical modeling

Shock waves are generated downstream of spillways during flood operations, which have adverse effects on spillway operations. This paper presents the physical model study of shock waves at the Mohmand Dam Spillway project, Pakistan. In this study, hydraulic analysis of shock waves was carried out to investigate its generation mechanism. Different experiments were performed to analyze the rooster tail on a flat spillway chute and to examine the factors affecting the characteristics of the rooster tail. The study results show that shock wave height is influenced by spillway chute slope, pier shape, and flow depth. Moreover, the height of the shock wave can be minimized by installing a semi-elliptical pier on the tail part of the main pier. Further modifications in the geometry of the extended tail part of the pier are recommended for the elimination of the shock wave. Based on observed data collected from the model study, an empirical equation was developed to estimate the shock wave height generated on the flat slope spillway chutes (5◦ to 10◦ )

Mental healthcare for young and adolescent LGBTQ+ individuals in the Indian subcontinent

The coronavirus disease (COVID-19) pandemic has led to a significant change in the way healthcare is dispensed. During the pandemic, healthcare inequities were experienced by various sections of society, based on gender, ethnicity, and socioeconomic status. The LGBTQ individuals were also affected by this inequity. There is a lack of information on this topic especially in the developing countries. Hence this issue requires further exploration and understanding. Previous literature briefly explored the mental, physical, and emotional turmoil faced by the LGBTQ community on a regular basis. They feared rejection by family and friends, bullying, physical assault, and religious biases. These issues prevented them from publicly speaking about their sexual orientation thereby making it difficult to collect reliable data. Although they require medical and psychological treatment, they are afraid to ask for help and access healthcare and mental health services. Being mindful of these difficulties, this article explores the various underlying causes of the mental health problems faced by LGBTQ individuals, especially, in the Indian subcontinent. The article also examines the status of healthcare services available to Indian sexual minorities and provides recommendations about possible remedial measures to ensure the well-being of LGBTQ individuals

Energy-Aware Scalable Reliable and Void-Hole Mitigation Routing for Sparsely Deployed Underwater Acoustic Networks

In wireless underwater sensor networks (WUSNs), network protocols for information routing are usually designed when a significant number of nodes are present in the network. Therefore, for sparse conditions, when a noticeable reduction in the number of nodes occurs, the performance of such protocols exhibits a degraded behavior pattern. To cope with routing issues when sparse conditions prevail, two routing algorithms for WUSNs are proposed in this paper. They are energy-aware scalable reliable and void-hole mitigation routing (ESRVR) and cooperative energy-aware scalable reliable and void-hole mitigation routing (Co-ESRVR). The ESRVR uses a number of strategies. Firstly, it uses two hop neighbors’ information to develop routing trajectories for information advancement, as one hop information cannot avoid a void-hole, a condition when a node is not able to find neighbors towards the sea surface, and more than two hop information is difficult to obtain when sparse conditions prevail. Secondly, when a void-hole still exists, the protocol uses a backward transmission mechanism to find other routing paths to deliver packets to the end target. Thirdly, the time by which a packet is held by a node prior to transmission is short for the nodes with low energy, depth and high count of neighbors. This reduces packets loss and avoids congestion of the channel. It also helps the nodes with no or few neighbors to hold the packet for a significant chunk of time until they find suitable neighbors, due to sea tides and currents, for further packets’ advancement. The Co-ESRVR further adds reliability to information advancement by adding routing in a cooperative fashion to ESRVR, which involves packets advancement to destination along two paths: directly from source and via a relayed path. This provides multiple paths for data advancement to the sea surface, so that if one path is badly affected by the harsh sea characteristics, others may not be. Unlike the counterpart protocol, the proposed algorithms are not dependent on a node’s geographical location or the distance from the sea surface, which increases their scalability and reduces the computational complexity. Performance analysis displays superior behavior patterns of the proposed algorithms over the counterpart in terms of the compared characteristics

Risk factors predisposing to congenital heart defects

Introduction: Congenital heart disease (CHD) is associated with multiple risk factors, consanguinity may be one such significant factor. The role of consanguinity in the etiology of CHD is supported by inbreeding studies, which demonstrate an autosomal recessive pattern of inheritance of some congenital heart defects. This study was done to find out the risk factors for CHD. Methods: A case-control study was done on pediatric Patients at a tertiary care hospital, Aga Khan University Hospital, located in Karachi, Pakistan. A total of 500 Patients, 250 cases and 250 controls were included in the study. Results: Amongst the 250 cases (i.e. those diagnosed with CHD), 122 Patients (48.8%) were born of consanguineous marriages while in the controls (i.e. non-CHD) only 72 Patients (28.9%) showed a consanguinity amongst parents. On multivariate analysis, consanguinity emerged as an independent risk factor for CHD, adjusted odds ratio 2.59 (95% C. I. 1.73 - 3.87). Other risk factors included low birth weight, maternal co-morbidities, family history of CHD and first born child. On the other hand, medications used by the mother during the index pregnancy, maternal age and gender of the child did not significantly increase the risk of developing CHD. Conclusions: Analyses of our results show that parental consanguinity, family history of CHD, maternal co-morbidities, first born child and low birth weight are independent risk factors for CHD

Mental healthcare for young and adolescent LGBTQ+ individuals in the Indian subcontinent

The coronavirus disease (COVID-19) pandemic has led to a significant change in the way healthcare is dispensed. During the pandemic, healthcare inequities were experienced by various sections of society, based on gender, ethnicity, and socioeconomic status. The LGBTQ individuals were also affected by this inequity. There is a lack of information on this topic especially in the developing countries. Hence this issue requires further exploration and understanding. Previous literature briefly explored the mental, physical, and emotional turmoil faced by the LGBTQ community on a regular basis. They feared rejection by family and friends, bullying, physical assault, and religious biases. These issues prevented them from publicly speaking about their sexual orientation thereby making it difficult to collect reliable data. Although they require medical and psychological treatment, they are afraid to ask for help and access healthcare and mental health services. Being mindful of these difficulties, this article explores the various underlying causes of the mental health problems faced by LGBTQ individuals, especially, in the Indian subcontinent. The article also examines the status of healthcare services available to Indian sexual minorities and provides recommendations about possible remedial measures to ensure the well-being of LGBTQ individuals

Methodological analysis of a community-based training initiative using the EPIS framework: an ongoing initiative to empower 10 million bystanders in CPR and bleeding control

Background Out-of-hospital cardiac arrest (OHCA) and life-threatening bleeding from trauma are leading causes of preventable mortality globally. Early intervention from bystanders can play a pivotal role in increasing the survival rate of victims. While great efforts for bystander training have yielded positive results in high-income countries, the same has not been replicated in low and middle-income countries (LMICs) due to resources constraints. This article describes a replicable implementation model of a nationwide program, aimed at empowering 10 million bystanders with basic knowledge and skills of hands-only cardiopulmonary resuscitation (CPR) and bleeding control in a resource-limited setting.Methods Using the EPIS (Exploration, Preparation, Implementation and Sustainment) framework, we describe the application of a national bystander training program, named ‘Pakistan Life Savers Programme (PLSP)’, in an LMIC. We discuss the opportunities and challenges faced during each phase of the program’s implementation and identify feasible and sustainable actions to make them reproducible in similar low-resource settings.Results A high mortality rate owing to OHCA and traumatic life-threatening bleeding was identified as a national issue in Pakistan. After intensive discussions during the exploration phase, PLSP was chosen as a potential solution. The preparation phase oversaw the logistical administration of the program and highlighted avenues using minimal resources to attain maximum outreach. National implementation of bystander training started as a pilot in suburban schools and expanded to other institutions, with 127 833 bystanders trained to date. Sustainability of the program was targeted through its addition in a single national curriculum taught in schools and the development of a cohesive collaborative network with entities sharing similar goals.Conclusion This article provides a methodological framework of implementing a national intervention based on bystander response. Such programs can increase bystander willingness and confidence in performing CPR and bleeding control, decreasing preventable deaths in countries having a high mortality burden.Level of evidence Level VI

Methodological analysis of a community-based training initiative using the EPIS framework: an ongoing initiative to empower 10 million bystanders in CPR and bleeding control

Background: Out-of-hospital cardiac arrest (OHCA) and life-threatening bleeding from trauma are leading causes of preventable mortality globally. Early intervention from bystanders can play a pivotal role in increasing the survival rate of victims. While great efforts for bystander training have yielded positive results in high-income countries, the same has not been replicated in low and middle-income countries (LMICs) due to resources constraints. This article describes a replicable implementation model of a nationwide program, aimed at empowering 10 million bystanders with basic knowledge and skills of hands-only cardiopulmonary resuscitation (CPR) and bleeding control in a resource-limited setting.Methods: Using the EPIS (Exploration, Preparation, Implementation and Sustainment) framework, we describe the application of a national bystander training program, named \u27Pakistan Life Savers Programme (PLSP)\u27, in an LMIC. We discuss the opportunities and challenges faced during each phase of the program\u27s implementation and identify feasible and sustainable actions to make them reproducible in similar low-resource settings.Results: A high mortality rate owing to OHCA and traumatic life-threatening bleeding was identified as a national issue in Pakistan. After intensive discussions during the exploration phase, PLSP was chosen as a potential solution. The preparation phase oversaw the logistical administration of the program and highlighted avenues using minimal resources to attain maximum outreach. National implementation of bystander training started as a pilot in suburban schools and expanded to other institutions, with 127 833 bystanders trained to date. Sustainability of the program was targeted through its addition in a single national curriculum taught in schools and the development of a cohesive collaborative network with entities sharing similar goals.Conclusion: This article provides a methodological framework of implementing a national intervention based on bystander response. Such programs can increase bystander willingness and confidence in performing CPR and bleeding control, decreasing preventable deaths in countries having a high mortality burden

A Hydraulic Analysis of Shock Wave Generation Mechanism on Flat Spillway Chutes through Physical Modeling

Shock waves are generated downstream of spillways during flood operations, which have adverse effects on spillway operations. This paper presents the physical model study of shock waves at the Mohmand Dam Spillway project, Pakistan. In this study, hydraulic analysis of shock waves was carried out to investigate its generation mechanism. Different experiments were performed to analyze the rooster tail on a flat spillway chute and to examine the factors affecting the characteristics of the rooster tail. The study results show that shock wave height is influenced by spillway chute slope, pier shape, and flow depth. Moreover, the height of the shock wave can be minimized by installing a semi-elliptical pier on the tail part of the main pier. Further modifications in the geometry of the extended tail part of the pier are recommended for the elimination of the shock wave. Based on observed data collected from the model study, an empirical equation was developed to estimate the shock wave height generated on the flat slope spillway chutes (5° to 10°)

Characterizing stomatal attributes and photosynthetic induction in relation to biochemical changes in Coriandrum sativum L. by foliar-applied zinc oxide nanoparticles under drought conditions

Abiotic stress, particularly drought, will remain an alarming challenge for sustainable agriculture. New approaches have been opted, such as nanoparticles (NPs), to reduce the negative impact of drought stress and lessen the use of synthetic fertilizers and pesticides that are an inevitable problem these days. The application of zinc oxide nanoparticles (ZnO NPs) has been recognized as an effective strategy to enhance plant growth and crop production during abiotic stress. The aim of the current study was to investigate the role of ZnO NPs in drought stress management of drought-susceptible Coriandrum sativum L. (C. sativum) in two consecutive seasons. Drought regimes (moderate drought regime—MDR and intensive drought regime—IDR) were developed based on replenishment method with respect to 50% field capacity of fully irrigated (control) plants. The results showed that foliar application of 100 ppm ZnO NPs improved the net photosynthesis (Pn), stomatal conductance (C), and transpiration rate (E) and boosted up the photosynthetic capacity associated with photosynthetic active radiation in MDR. Similarly, 48% to 30% improvement of chlorophyll b content was observed in MDR and onefold to 41% in IDR during both seasons in ZnO NP-supplemented plants. The amount of abscisic acid in leaves showed a decreasing trend in MDR and IDR in the first season (40% and 30%) and the second season (49% and 33%) compared with untreated ZnO NP plants. The ZnO NP-treated plants showed an increment in total soluble sugars, total phenolic content, and total flavonoid content in both drought regimes, whereas the abaxial surface showed high stomatal density and stomatal index than the adaxial surface in foliar-supplied NP plants. Furthermore, ZnO NPs improve the magnitude of stomata ultrastructures like stomatal length, stomatal width, and pore length for better adaptation against drought. Principal component analysis revealed the efficacy of ZnO NPs in inducing drought tolerance in moderate and intensive stress regimes. These results suggest that 100 ppm ZnO NPs can be used to ameliorate drought tolerance in C. sativum plants