Cosmological constraints from Radial Baryon Acoustic Oscillation measurements and Observational Hubble data

We use the Radial Baryon Acoustic Oscillation (RBAO) measurements, distant type Ia supernovae (SNe Ia), the observational $H(z)$ data (OHD) and the Cosmic Microwave Background (CMB) shift parameter data to constrain cosmological parameters of $\Lambda$CDM and XCDM cosmologies and further examine the role of OHD and SNe Ia data in cosmological constraints. We marginalize the likelihood function over $h$ by integrating the probability density $P\propto e^{-\chi^{2}/2}$ to obtain the best fitting results and the confidence regions in the $\Omega_{m}-\Omega_{\Lambda}$ plane.With the combination analysis for both of the {\rm $\Lambda$}CDM and XCDM models, we find that the confidence regions of 68.3%, 95.4% and 99.7% levels using OHD+RBAO+CMB data are in good agreement with that of SNe Ia+RBAO+CMB data which is consistent with the result of Lin et al's work. With more data of OHD, we can probably constrain the cosmological parameters using OHD data instead of SNe Ia data in the future.Comment: 8 pages, 6 figures, 2 tables, accepted for publication in Physics Letters

Human gene expression sensitivity according to large scale meta-analysis

<p>Abstract</p> <p>Background</p> <p>Genes show different sensitivities in expression corresponding to various biological conditions. Systematical study of this concept is required because of its important implications in microarray analysis etc. J.H. Ohn et al. first studied this gene property with yeast transcriptional profiling data.</p> <p>Results</p> <p>Here we propose a calculation framework for gene expression sensitivity analysis. We also compared the functions, centralities and transcriptional regulations of the sensitive and robust genes. We found that the robust genes tended to be involved in essential cellular processes. Oppositely, the sensitive genes perform their functions diversely. Moreover while genes from both groups show similar geometric centrality by coupling them onto integrated protein networks, the robust genes have higher vertex degree and betweenness than that of the sensitive genes. An interesting fact was also found that, not alike the sensitive genes, the robust genes shared less transcription factors as their regulators.</p> <p>Conclusion</p> <p>Our study reveals different propensities of gene expression to external perturbations, demonstrates different roles of sensitive genes and robust genes in the cell and proposes the necessity of combining the gene expression sensitivity in the microarray analysis.</p

Research in advance for FMD Novel Vaccines

Foot-and-Mouth Disease (FMD), as a major global animal disease, affects millions of animals worldwide and remains the main sanitary barrier to the international and national trade of animals and animal products. Inactivated vaccination is the most effective measure for prevention of FMD at present, but fail to induce long-term protection and content new requires for production of FMD vaccines. As a number of Researchers hope to obtain satisfactory novel vaccines by new bio-technology, novel vaccines have been studied for more than thirty years. Here reviews the latest research progress of new vaccines, summarizes some importance and raises several suggestions for the future of FMD vaccine

A highly sensitive detection for foot-and-mouth disease virus by gold nanopariticle improved immuno-PCR

<p>Abstract</p> <p>Backgroud</p> <p>Foot-and-mouth disease (FMD) is one of the most contagious of all artiodactyl animal diseases, and its infection has an obvious ability to spread over long distances and to contribute to epidemics in FMD-free areas. A highly sensitive and specific method is required to detect FMDV. In this study, we evaluated the usefulness of a bio-barcode assay (BCA) technique for detecting clinical samples of FMDV.</p> <p>Methods</p> <p>Highly sensitive gold nanopariticle (GNP) improved immuno-PCR (GNP-IPCR) which derived from the bio-barcode assay (BCA) was designed for the detection of FMDV. The target viral particles were captured by a polyclonal antibody coated on ELISA microplate, followed by adding GNP which was dually modified with oligonucleotides and a FMDV specific monoclonal antibody (MAb) 1D11 to form a sandwiched immune complex. After the formation of immuno-complex, the signal DNA was released by heating, and consequently characterized by PCR and real time PCR.</p> <p>Results</p> <p>The detection limit of GNP-PCR could reach to 10 fg/ml purified FMDV particles, and the assay can detect clinical samples of FMDV with highly sensitivity, while detect limit of conventional ELISA is 100 ng/ml in this study.</p> <p>Conclusion</p> <p>GNP-IPCR may provide a highly sensitive method for the detection of FMDV.</p

AI-accelerated Discovery of Altermagnetic Materials

Altermagnetism, a new magnetic phase, has been theoretically proposed and experimentally verified to be distinct from ferromagnetism and antiferromagnetism. Although altermagnets have been found to possess many exotic physical properties, the very limited availability of known altermagnetic materials (e.g., 14 confirmed materials) hinders the study of such properties. Hence, discovering more types of altermagnetic materials is crucial for a comprehensive understanding of altermagnetism and thus facilitating new applications in the next-generation information technologies, e.g., storage devices and high-sensitivity sensors. Here, we report 25 new altermagnetic materials that cover metals, semiconductors, and insulators, discovered by an AI search engine unifying symmetry analysis, graph neural network pre-training, optimal transport theory, and first-principles electronic structure calculation. The wide range of electronic structural characteristics reveals that various novel physical properties manifest in these newly discovered altermagnetic materials, e.g., anomalous Hall effect, anomalous Kerr effect, and topological property. Noteworthy, we discovered 8 i-wave altermagnetic materials for the first time. Overall, the AI search engine performs much better than human experts and suggests a set of new altermagnetic materials with unique properties, outlining its potential for accelerated discovery of the materials with targeting properties.Comment: 38 pages; 22 figures; 3 table

Domain wall partition function of the eight-vertex model with a non-diagonal reflecting end

With the help of the Drinfeld twist or factorizing F-matrix for the eight-vertex SOS model, we obtain the explicit determinant expression of the partition function of the eight-vertex model with a generic non-diagonal reflecting end and domain wall boundary condition. Our result shows that, contrary to the eight-vertex model without a reflection end, the partition function can be expressed as a single determinant.Comment: Latex file, 25 pages, 4 figures. arXiv admin note: substantial text overlap with arXiv:1107.562

Correction: Magnetoconductance modulations due to interlayer tunneling in radial superlattices

Correction for ‘Magnetoconductance modulations due to interlayer tunneling in radial superlattices’ by Yu-Jie Zhong et al., Nanoscale Horiz., 2022, 7, 168–173, https://doi.org/10.1039/D1NH00449B