Presentation_1.PDF

<p>Seven gene sets were significantly enriched for SNP associations with diabetes, and considered as potential diabetes pathways in a previous meta-analysis of diabetes GWAS. This study aims to examine if these gene sets also have expression associations with diabetes. The analysis was conducted using pooled data from 23 diabetes gene expression studies. Gene associations were examined using linear modeling with an empirical Bayes approach, and pathway associations were investigated by testing enrichment for significant genes. Meta-analyses were performed to investigate gene and pathway associations in all studies and tissue types. The analysis showed that six gene sets and three member genes of ACADSB, RASSF2, and KLF12 had significant associations with diabetes traits. The findings suggest that these gene sets are related to diabetes regulation, and their functions tend to be tissue non-specific.</p

Additional file 1 of Correlations between multimodal neuroimaging and peripheral inflammation in different subtypes and mood states of bipolar disorder: a systematic review

Additional file 1. Search strategy using keywords according to the databases

Presentation_1_Grade-control outdoor turning flight of robo-pigeon with quantitative stimulus parameters.pdf

IntroductionThe robo-pigeon using homing pigeons as a motion carrier has great potential in search and rescue operations due to its superior weight-bearing capacity and sustained flight capabilities. However, before deploying such robo-pigeons, it is necessary to establish a safe, stable, and long-term effective neuro-electrical stimulation interface and quantify the motion responses to various stimuli.MethodsIn this study, we investigated the effects of stimulation variables such as stimulation frequency (SF), stimulation duration (SD), and inter-stimulus interval (ISI) on the turning flight control of robo-pigeons outdoors, and evaluated the efficiency and accuracy of turning flight behavior accordingly.ResultsThe results showed that the turning angle can be significantly controlled by appropriately increasing SF and SD. Increasing ISI can significantly control the turning radius of robotic pigeons. The success rate of turning flight control decreases significantly when the stimulation parameters exceed SF > 100 Hz or SD > 5 s. Thus, the robo-pigeon's turning angle from 15 to 55° and turning radius from 25 to 135 m could be controlled in a graded manner by selecting varying stimulus variables.DiscussionThese findings can be used to optimize the stimulation strategy of robo-pigeons to achieve precise control of their turning flight behavior outdoors. The results also suggest that robo-pigeons have potential for use in search and rescue operations where precise control of flight behavior is required.</p

Impact of Processing Effects on Surface Segregation of Bottlebrush Polymer Additives

The surface properties of polymeric materials govern interactions with the surroundings and are responsible for various application-relevant properties. Recent studies have shown that bottlebrush polymers can be used to modify the surface chemistry of the polymers because they spontaneously segregate to the interfaces when they are blended with the linear polymers, driven in large part by entropic effects that arise from the unique architecture of bottlebrush polymers. However, while prior work has largely focused on equilibrium segregation profiles, kinetic and processing effects can also drive bottlebrush additives to surfaces and interfaces. In solution-cast blends of polymers and colloids, vertical stratification is controlled by the relative Péclet (Pe) numbers of the constituents, i.e., the relative rates of solvent evaporation and solute diffusion. Herein, we studied processing effects that drive bottlebrush additives to interfaces when blended with linear polymers. We prepared blends of bottlebrush polystyrene (BBPS) and linear perdeuterated polystyrene (dPS), where the BBPS side-chain length was fixed at Nsc = 48, the BBPS backbone length ranged from Nb = 30–260, and the dPS chain length ranged from Nm = 40–548. The relative Pe numbers of BBPS and dPS were varied by changing the solvent and sizes of BBPS and dPS. In contrast to other binary blends where the constituents have disparate sizes (e.g., colloid/colloid, polymer/colloid, and polymer/polymer), we found that the relative Pe number cannot account for the degree of segregation observed in these bottlebrush and linear polymer blends. For a fixed BBPS side-chain length, we observe stronger surface segregation of bottlebrush additives when the blend is cast using lower boiling point solvents and/or for blends with longer bottlebrush polymers. We further show that solvent annealing of the film can increase the enrichment of bottlebrush additives near surfaces. This study provides insight into the interplay of processing effects and blend thermodynamics that govern surface segregation of bottlebrush polymer additives

OSA results: chromosome 3 conditional on chromosome 5, replicates with -values 0

<p><b>Copyright information:</b></p><p>Taken from "Searching for epistatic interactions in nuclear families using conditional linkage analysis"</p><p></p><p>BMC Genetics 2005;6(Suppl 1):S148-S148.</p><p>Published online 30 Dec 2005</p><p>PMCID:PMC1866787.</p><p></p>0006

Mixed Ionic–Electronic Conduction Increases the Rate Capability of Polynaphthalenediimide for Energy Storage

Conjugated polymers offer a number of unique and useful properties for use as battery electrodes, and recent work has reported that conjugated polymers can exhibit excellent rate performance due to electron transport along the polymer backbone. However, the rate performance depends on both ion and electron conduction, and strategies for increasing the intrinsic ionic conductivities of conjugated polymer electrodes are lacking. Here, we investigate a series of conjugated polynapthalene dicarboximide (PNDI) polymers containing oligo(ethylene glycol) (EG) side chains that enhance ion transport. We produced PNDI polymers with varying contents of alkylated and glycolated side chains and investigated the impact on rate performance, specific capacity, cycling stability, and electrochemical properties through a series of charge–discharge, electrochemical impedance spectroscopy, and cyclic voltammetry measurements. We find that the incorporation of glycolated side chains results in electrode materials with exceptional rate performance (up to 500C, 14.4 s per cycle) in thick (up to 20 μm), high-polymer-content (up to 80 wt %) electrodes. Incorporation of EG side chains enhances both ionic and electronic conductivities, and we found that PNDI polymers with at least 90% of NDI units containing EG side chains functioned as carbon-free polymer electrodes. This work demonstrates that polymers with mixed ionic and electronic conduction are excellent candidates for battery electrodes with good cycling stability and capable of ultra-fast rate performance

Mean levels (standard deviation) of study variables by sex.

<p>*Difference in birth weight was adjusted for gestational age; difference in weight, height and BMI was adjusted for age.</p

Major effects of genotypes for candidate SNPs on repeated measures of (A) childhood BMI and (B) adulthood BMI, adjusted for age and birth weight.

<p>Major effects of genotypes for candidate SNPs on repeated measures of (A) childhood BMI and (B) adulthood BMI, adjusted for age and birth weight.</p

Characteristic of candidate SNPs.

<p>Strand: + (sense strand) and − (antisense strand); Position (bp): It is based on coordinates of NCBI B36. A1/A2: Minor Allele/Major Allele; MAF: Minor Allele Frequency; GWAS_P: previously reported GWAS p-value; HWE_P: The p-value of Hardy-Weinberg Equilibrium test.</p

FTO regional linkage disequilibrium (LD) and recombination rate.

<p>The LD is from HapMap rel. 27 and the recombination rate is from HapMap rel. 22. SNP position is based on NCBI build 36 of the human genome.</p