HUMAN WHARTON'S JELLY STEM CELLS AND/OR ITS EXTRACT FOR THE MANAGEMENT OF HEMATOLOGICAL MALIGNANCIES AND BLOOD DISORDERS

Ph.DDOCTOR OF PHILOSOPH

Is Arm software ecosystem ready for HPC?

In recent years, the HPC community has increasingly grown its interest towards the Arm architecture with research projects targeting primarily the installation of Arm-based clusters. State of the art research project examples are the European Mont-Blanc, the Japanese Post-K, and the UKs GW4/EPSRC. Primarily attention is usually given to hardware platforms, and the Arm HPC community is growing as the hardware is evolving towards HPC workloads via solutions borrowed from mobile market e.g., big.LITTLE and additions such as Armv8-A Scalable Vector Extension (SVE) technology. However the availability of a mature software ecosystem and the possibility of running large and complex HPC applications plays a key role in the consolidation process of a new technology, especially in a conservative market like HPC. For this reason in this poster we present a preliminary evaluation of the Arm system software ecosystem, limited here to the Arm HPC Compiler and the Arm Performance Libraries, together with a porting and testing of three fairly complex HPC code suites: QuantumESPRESSO, WRF and FEniCS. The selection of these codes has not been totally random: they have been in fact proposed as HPC challenges during the last two editions of the Student Cluster Competition at ISC where all the authors have been involved operating an Arm-based cluster and awarded with the Fan Favorite award.The research leading to these results has received funding from the European Community's Seventh Framework Programme [FP7/2007-2013] and Horizon 2020 under the Mont-Blanc projects [3], grant agreements n. 288777, 610402 and 671697. The authors would also like to thank E4 Computer Engineering for providing part of the hardware resources needed for the evaluation carried out in this poster as well as for greatly supporting the Student Cluster Competition team.Postprint (author's final draft

New fermions on the line in topological symmorphic metals

Topological metals and semimetals (TMs) have recently drawn significant interest. These materials give rise to condensed matter realizations of many important concepts in high-energy physics, leading to wide-ranging protected properties in transport and spectroscopic experiments. The most studied TMs, i.e., Weyl and Dirac semimetals, feature quasiparticles that are direct analogues of the textbook elementary particles. Moreover, the TMs known so far can be characterized based on the dimensionality of the band crossing. While Weyl and Dirac semimetals feature zero-dimensional points, the band crossing of nodal-line semimetals forms a one-dimensional closed loop. In this paper, we identify a TM which breaks the above paradigms. Firstly, the TM features triply-degenerate band crossing in a symmorphic lattice, hence realizing emergent fermionic quasiparticles not present in quantum field theory. Secondly, the band crossing is neither 0D nor 1D. Instead, it consists of two isolated triply-degenerate nodes interconnected by multi-segments of lines with two-fold degeneracy. We present materials candidates. We further show that triplydegenerate band crossings in symmorphic crystals give rise to a Landau level spectrum distinct from the known TMs, suggesting novel magneto-transport responses. Our results open the door for realizing new topological phenomena and fermions including transport anomalies and spectroscopic responses in metallic crystals with nontrivial topology beyond the Weyl/Dirac paradigm.Comment: 24 pages, 4 figures, and 1 tabl