Novel Genetic Loci for CAD Identified by GWLS in the GeneQuest Families.

a<p>Based on Marshfield Medical Genetics marker set 11.</p>b<p>Based on either UCSC Genome Browser database or Marshfield Medical Genetics marker set 11.</p><p>Note that a marker with a two-point or multipoint NPL score of >4.99 (<i>P</i><3×10⁻⁷) was considered to be linked to CAD highly significantly; A two-point or multipoint NPL score between 3.18 and 4.08 indicates suggestive linkage <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113935#pone.0113935-Kruglyak1" target="_blank">[38]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113935#pone.0113935-Kruglyak2" target="_blank">[53]</a>.</p><p>Novel Genetic Loci for CAD Identified by GWLS in the GeneQuest Families.</p

Clinical and Demographic Features of the Study Populations (GeneQuest)^*.

<p>*From Wang et al and Shen et al <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113935#pone.0113935-Shen1" target="_blank">[31]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113935#pone.0113935-Wang4" target="_blank">[33]</a>.</p><p>Clinical and Demographic Features of the Study Populations (GeneQuest)^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113935#nt101" target="_blank">*</a>}.</p

Genome-wide NPL scan for CAD-susceptibility loci on chromosomes 10–18 in the GeneQuest families.

<p>Genome-wide NPL scan for CAD-susceptibility loci on chromosomes 10–18 in the GeneQuest families.</p