Summary of patient baseline characteristics according to the development of hypertension.

<p>Summary of patient baseline characteristics according to the development of hypertension.</p

Cox regression analysis of risk factors for hypertension development.

<p>Cox regression analysis of risk factors for hypertension development.</p

Patient flow chart.

<p>Patient flow chart.</p

Kaplan-Meier survival estimates of hypertension development according to the independent risk factors at baseline: age (left), body mass index (centre) and estimated glomerular filtration rate (right).

<p>BMI: body mass index; eGFR: estimated glomerular filtration rate.</p

Summary of patient baseline characteristics according to patient follow-up status.

<p>Summary of patient baseline characteristics according to patient follow-up status.</p

Manhattan plot of the associations between viral load (VL) and Shannon entropy at AA positions projected on the HIV genome.

Red horizontal line marks the Bonferroni p-value threshold (p = 2.0×10−5). The x-axis denotes gene AA positions. A total of 2,447 HIV AA positions are shown on the x-axis. Gag positions 1–239, Pol positions 981–1004, Rev positions 1–6 and Tat positions 1–51 are not shown, as they were not covered by the amplicons.</p

Linear regression analysis of predictors of the viral load (VL).

(DOCX)</p

The density plots of the mean Shannon entropy in different races of the 36 most variable positions.

(DOCX)</p

The relationship between sample’s mean Shannon entropy, viral load (VL) and infection duration.

The relationship between sample’s mean Shannon entropy, viral load (VL) and infection duration.</p

Pairwise correlation matrix between covariates (bottom triangle).

(DOCX)</p