A Computationally Efficient Tool for Assessing the Depth Resolution in Potential-Field Inversion

In potential-field inversion problems, it can be difficult to obtain reliable information about the source distribution with respect to depth. Moreover, spatial resolution of the solution decreases with depth, and in fact the more ill-posed the problem – and the more noisy the data – the less reliable the depth information. Based on early work in depth resolution, defined in terms of the singular value decomposition, we introduce a tool APPROXDRP which uses an approximation of the singular vectors obtained by the iterative Lanczos bidiagonalization algorithm, making it well suited for large-scale problems. This tool allows a computational/visual analysis of how much the depth resolution in a computational potential-field inversion problem can be obtained from the given data.We show that when used in combination with a plot of the approximate SVD quantities, APPROXDRP may successfully show the limitations of depth resolution resulting from noise in the data. This allows a reliable analysis of the retrievable depth information and effectively guides the user in choosing the optimal number of iterations, for a given problem

TOWARDS SME GROWTH: RPA AS AN INTERVENTION TECHNOLOGY IN ACTION DESIGN RESEARCH

Small to medium enterprises are in a constant battle of stabilising internal support and development processes vs their external growth potential. Identifying fitting technologies that can support this stabilisation while still enabling scalable growth is a difficult challenge, especially for practitioners who want to maximise productivity rather than getting in a perpetual state of learning and developing new technologies. In this study we use action design research to establish two robotic process automation interventions in an SME to identify the technological design features that technology interventions should have to establish stabilised and balanced internal and external growth processes. In this Research-In-Progress we work in close cooperation with the firm Lindgaard Pedersen to attempt implementing RPAs in their business to explore different design features that can help establish a proper implementation of RPA in a small to medium enterprise setting

Gut bacteria and necrotizing enterocolitis: cause or effect?

Development of necrotising enterocolitis (NEC) is considered to be dependent on the bacterial colonisation of the gut. With little concordance between published data and a recent study failing to detect a common strain in infants with NEC, more questions than answers are arising about our understanding of this complex disease

Gene expression of the endolymphatic sac

Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters