Association between (A) the maximum urinary calprotectin increase and ischaemic time and (B) the maximum urinary NGAL increase and ischaemic time in Group 1 (NSS with renal ischaemia) in a linear regression model, as assessed by Spearman’s correlation test.

<p>Regression lines are plotted. Linear regression model: A: R = 0.16, B = 103.61 (95% CI -219.96–427.19), p = 0.51; B: R = 0.09, B = 1.71 (95% CI -7.88–11.31), p = 0.71. Spearman’s correlation: A: R = 0.29 (95% CI -0.19–0.66), p = 0.21; B: R = 0.26 (95% CI -0.22–0.64), p = 0.26. NSS, nephron sparing surgery for kidney tumours; B, regression co-efficient, slope of the regression line; R, correlation co-efficient; CI, confidence interval.</p

Concentrations of (A) urinary calprotectin, (B) urinary neutrophil gelatinase—associated lipocalin (NGAL), (C) plasma creatinine, and (D) the estimated glomerular filtration rate (eGFR) in patients undergoing nephron sparing surgery (NSS) for kidney tumours with renal pedicle clamping (renal ischaemia, Group 1) or without renal ischaemia (Group 2), and in patients undergoing radical nephrectomy for living kidney donation (Group 3).

<p>Data are presented as median and interquartile range. Asterisks indicate significant changes from baseline in a non-parametric analysis of variance (Kruskal-Wallis test, corrected for multiple comparisons by Dunn’s test as a post hoc pairwise multiple comparison). p.o., post-operative. * p < 0.05, ** p < 0.01, *** p < 0.001.</p