Thermal Control of Spin Excitations in the Coupled Ising-Chain Material RbCoCl₃

We have used neutron spectroscopy to investigate the spin dynamics of the quantum (S = 1/2) antiferromagnetic Ising chains in RbCoCl3. The structure and magnetic interactions in this material conspire to produce two magnetic phase transitions at low temperatures, presenting an ideal opportunity for thermal control of the chain environment. The high-resolution spectra we measure of two-domain-wall excitations therefore characterize precisely both the continuum response of isolated chains and the "Zeeman-ladder" bound states of chains in three different effective staggered fields in one and the same material. We apply an extended Matsubara formalism to obtain a quantitative description of the entire dataset, Monte Carlo simulations to interpret the magnetic order, and finite-temperature density-matrix renormalization-group calculations to fit the spectral features of all three phases

Molecular Tweezers with Varying Anions: A Comparative Study

Selective binding of the phosphate-substituted molecular tweezer 1a to protein lysine residues was suggested to explain the inhibition of certain enzymes and the aberrant aggregation of amyloid petide Aβ42 or α-synuclein, which are assumed to be responsible for Alzheimer’s and Parkinson’s disease, respectively. In this work we systematically investigated the binding of four water-soluble tweezers 1a−d (substituted by phosphate, methanephosphonate, sulfate, or O-methylenecarboxylate groups) to amino acids and peptides containing lysine or arginine residues by using fluorescence spectroscopy, NMR spectroscopy, and isothermal titration calorimetry (ITC). The comparison of the experimental results with theoretical data obtained by a combination of QM/MM and ab initio 1H NMR shift calculations provides clear evidence that the tweezers 1a−c bind the amino acid or peptide guest molecules by threading the lysine or arginine side chain through the tweezers’ cavity, whereas in the case of 1d the guest molecule is preferentially positioned outside the tweezer’s cavity. Attractive ionic, CH-π, and hydrophobic interactions are here the major binding forces. The combination of experiment and theory provides deep insight into the host−guest binding modes, a prerequisite to understanding the exciting influence of these tweezers on the aggregation of proteins and the activity of enzymes

The structure of black hole magnetospheres. I. Schwarzschild black holes

We introduce a multipolar scheme for describing the structure of stationary, axisymmetric, force-free black-hole magnetospheres in the ``3+1'' formalism. We focus here on Schwarzschild spacetime, giving a complete classification of the separable solutions of the stream equation. We show a transparent term-by-term analogy of our solutions with the familiar multipoles of flat-space electrodynamics. We discuss electrodynamic processes around disk-fed black holes in which our solutions find natural applications: (a) ``interior'' solutions in studies of the Blandford-Znajek process of extracting the hole's rotational energy, and of the formation of relativistic jets in active galactic nuclei and ``microquasars'', and, (b) ``exterior'' solutions in studies of accretion disk dynamos, disk-driven winds and jets. On the strength of existing numerical studies, we argue that the poloidal field structures found here are also expected to hold with good accuracy for rotating black holes, except for maximum possible rotation rates. We show that the closed-loop exterior solutions found here are not in contradiction with the Macdonald-Thorne theorem, since these solutions, which diverge logarithmically on the hole's horizon $\cal H$, apply only to those regions which exclude $\cal H$.Comment: 6 figures. Accepted for publication by MNRA

The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression

© 2014 Elsevier Inc.Proper chromosome segregation during meiosis requires the assembly of the synaptonemal complex (SC) between homologous chromosomes. However, the SC structure itself is indifferent to homology, andpoorly understood mechanisms that depend on conserved HORMA-domain proteins prevent ectopic SC assembly. Although HORMA-domain proteins are thought to regulate SC assembly as intrinsic components of meiotic chromosomes, here we uncover a key role for nuclear soluble HORMA-domain protein HTP-1 in the quality control of SC assembly. We show that a mutant form of HTP-1 impaired in chromosome loading provides functionality of an HTP-1-dependent checkpoint that delays exit from homology search-competent stages until all homolog pairs are linked by the SC. Bypassing of this regulatory mechanism results in premature meiotic progression and licensing of homology-independent SC assembly. These findings identify nuclear soluble HTP-1 as a regulator of early meiotic progression, suggesting parallels with the mode of action of Mad2 in the spindle assembly checkpoint

Coulomb field of an accelerated charge: physical and mathematical aspects

The Maxwell field equations relative to a uniformly accelerated frame, and the variational principle from which they are obtained, are formulated in terms of the technique of geometrical gauge invariant potentials. They refer to the transverse magnetic (TM) and the transeverse electric (TE) modes. This gauge invariant "2+2" decomposition is used to see how the Coulomb field of a charge, static in an accelerated frame, has properties that suggest features of electromagnetism which are different from those in an inertial frame. In particular, (1) an illustrative calculation shows that the Larmor radiation reaction equals the electrostatic attraction between the accelerated charge and the charge induced on the surface whose history is the event horizon, and (2) a spectral decomposition of the Coulomb potential in the accelerated frame suggests the possibility that the distortive effects of this charge on the Rindler vacuum are akin to those of a charge on a crystal lattice.Comment: 27 pages, PlainTex. Related papers available at http://www.math.ohio-state.edu/~gerlac

Electrostatic boundary value problems in the Schwarzschild background

The electrostatic potential of any test charge distribution in Schwarzschild space with boundary values is derived. We calculate the Green's function, generalize the second Green's identity for p-forms and find the general solution. Boundary value problems are solved. With a multipole expansion the asymptotic property for the field of any charge distribution is derived. It is shown that one produces a Reissner--Nordstrom black hole if one lowers a test charge distribution slowly toward the horizon. The symmetry of the distribution is not important. All the multipole moments fade away except the monopole. A calculation of the gravitationally induced electrostatic self-force on a pointlike test charge distribution held stationary outside the black hole is presented.Comment: 18 pages, no figures, uses iopart.st

Scalar field and electromagnetic perturbations on Locally Rotationally Symmetric spacetimes

We study scalar field and electromagnetic perturbations on Locally Rotationally Symmetric (LRS) class II spacetimes, exploiting a recently developed covariant and gauge-invariant perturbation formalism. From the Klein-Gordon equation and Maxwell's equations, respectively, we derive covariant and gauge-invariant wave equations for the perturbation variables and thereby find the generalised Regge-Wheeler equations for these LRS class II spacetime perturbations. As illustrative examples, the results are discussed in detail for the Schwarzschild and Vaidya spacetime, and briefly for some classes of dust Universes.Comment: 22 pages; v3 has minor changes to match published versio

The self-force on a static scalar test-charge outside a Schwarzschild black hole

The finite part of the self-force on a static scalar test-charge outside a Schwarzschild black hole is zero. By direct construction of Hadamard's elementary solution, we obtain a closed-form expression for the minimally coupled scalar field produced by a test-charge held fixed in Schwarzschild spacetime. Using the closed-form expression, we compute the necessary external force required to hold the charge stationary. Although the energy associated with the scalar field contributes to the renormalized mass of the particle (and thereby its weight), we find there is no additional self-force acting on the charge. This result is unlike the analogous electrostatic result, where, after a similar mass renormalization, there remains a finite repulsive self-force acting on a static electric test-charge outside a Schwarzschild black hole. We confirm our force calculation using Carter's mass-variation theorem for black holes. The primary motivation for this calculation is to develop techniques and formalism for computing all forces - dissipative and non-dissipative - acting on charges and masses moving in a black-hole spacetime. In the Appendix we recap the derivation of the closed-form electrostatic potential. We also show how the closed-form expressions for the fields are related to the infinite series solutions.Comment: RevTeX, To Appear in Phys. Rev.

An Action for Black Hole Membranes

The membrane paradigm is the remarkable view that, to an external observer, a black hole appears to behave exactly like a dynamical fluid membrane, obeying such pre-relativistic equations as Ohm's law and the Navier-Stokes equation. It has traditionally been derived by manipulating the equations of motion. Here we provide an action formulation of this picture, clarifying what underlies the paradigm, and simplifying the derivations. Within this framework, we derive previous membrane results, and extend them to dyonic black hole solutions. We discuss how it is that an action can produce dissipative equations. Using a Euclidean path integral, we show that familiar semi-classical thermodynamic properties of black holes also emerge from the membrane action. Finally, in a Hamiltonian description, we establish the validity of a minimum entropy production principle for black holes.Comment: LaTeX, 30 Pages, minor editorial change