3 research outputs found
An FMRI-Compatible Symbol Search Task
- Author
- Publication venue
- 'Cambridge University Press (CUP)'
- Publication date
- Field of study
Optimizing Spatial Biopsy Sampling for the Detection of Prostate Cancer
- Author
- Publication venue
- eScholarship, University of California
- Publication date
- 28/04/2021
- Field of study
PurposeThe appropriate number of systematic biopsy cores to retrieve during magnetic resonance imaging (MRI)-targeted prostate biopsy is not well defined. We aimed to demonstrate a biopsy sampling approach that reduces required core count while maintaining diagnostic performance.Materials and methodsWe collected data from a cohort of 971 men who underwent MRI-ultrasound fusion targeted biopsy for suspected prostate cancer. A regional targeted biopsy (RTB) was evaluated retrospectively; only cores within 2 cm of the margin of a radiologist-defined region of interest were considered part of the RTB. We compared detection rates for clinically significant prostate cancer (csPCa) and cancer upgrading rate on final whole mount pathology after prostatectomy between RTB, combined, MRI-targeted, and systematic biopsy.ResultsA total of 16,459 total cores from 971 men were included in the study data sets, of which 1,535 (9%) contained csPCa. The csPCa detection rates for systematic, MRI-targeted, combined, and RTB were 27.0% (262/971), 38.3% (372/971), 44.8% (435/971), and 44.0% (427/971), respectively. Combined biopsy detected significantly more csPCa than systematic and MRI-targeted biopsy (p <0.001 and p=0.004, respectively) but was similar to RTB (p=0.71), which used on average 3.8 (22%) fewer cores per patient. In 102 patients who underwent prostatectomy, there was no significant difference in upgrading rates between RTB and combined biopsy (p=0.84).ConclusionsA RTB approach can maintain state-of-the-art detection rates while requiring fewer retrieved cores. This result informs decision making about biopsy site selection and total retrieved core count
An Overview of SOM Literature
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- T Kohonen
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- T Koizumi
- T Komori
- T Lee
- T Li
- T Lu
- T Lu
- T Martinetz
- T Martinetz
- T Martinetz
- T Martinetz
- T Martinetz
- T Martinetz
- T Pomierski
- T Räsänen
- T Röfer
- T Rögnvaldsson
- T Shen
- T Shen
- T Shen
- T Shen
- T Sorsa
- T Sorsa
- T Sorsa
- T Tanaka
- T Villmann
- T Villmann
- T Yamaguchi
- T Yamaguchi
- T Yamaguchi
- T Yamaguchi
- T Yamaguchi
- T Yoshihara
- T-C Lee
- T-D Chiueh
- T-P Jung
- TL Huntsberger
- TM English
- TM English
- TM Heskes
- TM Martinetz
- TM Martinetz
- TR Anderson
- TR Damarla
- U Dagitan
- U Nehmzow
- U Nehmzow
- U Nehmzow
- U Nehmzow
- UR Zimmer
- V Chandrasekaran
- V Chandrasekaran
- V Cherkassky
- V Cherkassky
- V Cherkassky
- V Cherkassky
- V Cherkassky
- V Cherkassky
- V Cherkassky
- V Demian
- V Demian
- V Pang
- V Peiris
- V Peiris
- V Peiris
- V Peiris
- V Tryba
- V Tryba
- V Tryba
- V Tryba
- V Tryba
- V Tryba
- V Tryba
- V Tryba
- VR Sa de
- VS Smolin
- VT Ruoppila
- VV Tolat
- VV Tolat
- VZ Kepuska
- VZ Kepuska
- VZ Kepuska
- VZ Kepuska
- W Banzhaf
- W Barry
- W Chang
- W Cheng
- W Fakhr
- W Fakhr
- W Fushuan
- W Gong
- W Kessler
- W Pedrycz
- W Poechmueller
- W Snyder
- W Suewatanakul
- W Trumper
- W Wan
- W Wan
- W Wan
- W Wang
- W Xinwen
- W-C Fang
- WC Lin
- WD Smart
- WF Recla
- WJ Maurer
- WJ Maurer
- WJ Meissen
- WK Tsai
- WR Kirkland
- WS Kim
- WX Wen
- WY Yan
- X Chen
- X Driancourt
- X Driancourt
- X Jiang
- X Li
- X Lin
- X Liu
- X Magnisalis
- X Zhang
- Y Bartal
- Y Bennani
- Y Bennani
- Y Bennani
- Y Bennani
- Y Cai
- Y Cheng
- Y Cheng
- Y Coiton
- Y He
- Y Idan
- Y Jilai
- Y Kojima
- Y Kuramoti
- Y Lee
- Y Lirov
- Y Lirov
- Y Matsuyama
- Y Sakuraba
- Y Sakuraba
- Y Sakuraba
- Y-C Lai
- Y-H Pao
- Y-Y Hsu
- YH Shin
- YT So
- Z Bing
- Z He
- Z Huang
- Z Wang
- Z Zhao
- Z Zhao
- Z Zhao
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-P Lo
- Z-Z Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1995
- Field of study