8 research outputs found

    Additional file 2: of PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts

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    Table S1. Multivariate linear mixed models to analyze the time-varying effect of the PTGER4 rs6896969 variant in radiographic joint damage of the HCSC-RAC, PEARL, and PAZ cohorts. Table S2. Single-nucleotide polymorphisms with p < 0.05 in the constant effect pooled analysis from the discovery cohorts. Table S3. Single-nucleotide polymorphisms with p < 0.05 in the time-varying effect pooled analysis from the discovery cohorts. Table S4. Single-nucleotide polymorphisms selected for replication in the constant effect analysis and their associations with radiological joint damage in the six cohorts. Table S5. Single-nucleotide polymorphisms selected for replication in the time-varying effect analysis and their associations with radiological joint damage in the six cohorts. (DOC 325 kb

    Additional file 1: of PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts

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    Figure S1. Region analyzed in the fine-mapping analysis. Figure S2. Linkage disequilibrium blocks among the significant SNPs (pooled p < 0.05) from the constant effect analysis. Figure S3. Linkage disequilibrium blocks among the significant SNPs (pooled p < 0.05) from the time-varying effect analysis. (DOC 845 kb

    Additional file 2: of An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting

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    Baseline characteristics of anti-CCP-2-negative RA patients. Baseline characteristics of anti-CCP-2-negative RA patients (nñ€‰=ñ€‰279) that are multiplex-negative or -positive. CCP cyclic citrullinated peptide, RA rheumatoid arthritis. (PDF 40 kb

    Additional file 1: of An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting

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    Diagnosis of anti-CCP-2-negative non-RA patients. Diagnoses of anti-CCP-2-negative non-RA patients (n = 135) as assessed by an experienced rheumatologist after 1 year of follow-up stratified for multiplex positivity. CCP cyclic citrullinated peptide, RA rheumatoid arthritis. (PDF 14 kb
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