6,787 research outputs found
Thermodynamic equilibrium and its stability for Microcanonical systems described by the Sharma-Taneja-Mittal entropy
It is generally assumed that the thermodynamic stability of equilibrium state
is reflected by the concavity of entropy. We inquire, in the microcanonical
picture, on the validity of this statement for systems described by the
bi-parametric entropy of Sharma-Taneja-Mittal. We analyze
the ``composability'' rule for two statistically independent systems, A and B,
described by the entropy with the same set of the deformed
parameters. It is shown that, in spite of the concavity of the entropy, the
``composability'' rule modifies the thermodynamic stability conditions of the
equilibrium state. Depending on the values assumed by the deformed parameters,
when the relation holds (super-additive systems), the concavity
conditions does imply the thermodynamics stability. Otherwise, when the
relation holds (sub-additive systems), the concavity
conditions does not imply the thermodynamical stability of the equilibrium
state.Comment: 13 pages, two columns, 1 figure, RevTex4, version accepted on PR
Soliton response to transient trap variations
The response of bright and dark solitons to rapid variations in an expulsive
longitudinal trap is investigated. We concentrate on the effect of transient
changes in the trap frequency in the form of temporal delta kicks and the
hyperbolic cotangent functions. Exact expressions are obtained for the soliton
profiles. This is accomplished using the fact that a suitable linear
Schrodinger stationary state solution in time can be effectively combined with
the solutions of non-linear Schrodinger equation, for obtaining solutions of
the Gross-Pitaevskii equation with time dependent scattering length in a
harmonic trap. Interestingly, there is rapid pulse amplification in certain
scenarios
Electron elastic scattering cross sections from 1 keV to 100 MeV for elements Z = 1 to 100
Tables of electron elastic scattering differential cross sections of elements (Z = 1 to 100) are given for electron energies in the range of 1 keV to 100 MeV and scattering angles in the range of 1 to 179. The function describing the asymmetry of a polarized electron beam after the scattering process is also included in the tables. (auth
Fractional periodicity and magnetism of extended quantum rings
The magnetic properties and nature of the persistent current in small
flux-penetrated rings are investigated. An effective rigid-rotator
description is formulated for this system, which coincides with a transition to
a ferromagnetic state in the model. The criteria for the onset of effective
rigid rotation is given. The model is used to understand continuum model
ground-state solutions for a 2D few-particle hard-wall quantum dot, where
ferromagnetic solutions are found even without the Zeeman coupling to spin.
After the onset of effective rigid rotation, a 97--98% correspondence can be
determined between the lattice model and continuum model eigenstate results
Determinants on lens spaces and cyclotomic units
The Laplacian functional determinants for conformal scalars and coexact
one-forms are evaluated in closed form on inhomogeneous lens spaces of certain
orders, including all odd primes when the essential part of the expression is
given, formally as a cyclotomic unitComment: 18 pages, 1 figur
Accurate sample assignment in a multiplexed, ultrasensitive, high-throughput sequencing assay for minimal residual disease
High-throughput sequencing (HTS) (next-generation sequencing) of the rearranged Ig and T-cell receptor genes promises to be less expensive and more sensitive than current methods of monitoring minimal residual disease (MRD) in patients with acute lymphoblastic leukemia. However, the adoption of new approaches by clinical laboratories requires careful evaluation of all potential sources of error and the development of strategies to ensure the highest accuracy. Timely and efficient clinical use of HTS platforms will depend on combining multiple samples (multiplexing) in each sequencing run. Here we examine the Ig heavy-chain gene HTS on the Illumina MiSeq platform for MRD. We identify errors associated with multiplexing that could potentially impact the accuracy of MRD analysis. We optimize a strategy that combines high-purity, sequence-optimized oligonucleotides, dual indexing, and an error-aware demultiplexing approach to minimize errors and maximize sensitivity. We present a probability-based, demultiplexing pipeline Error-Aware Demultiplexer that is suitable for all MiSeq strategies and accurately assigns samples to the correct identifier without excessive loss of data. Finally, using controls quantified by digital PCR, we show that HTS-MRD can accurately detect as few as 1 in 10(6) copies of specific leukemic MRD
Copy number gain at 12q12-14 may be important in the transformation from follicular lymphoma to diffuse large B cell lymphoma
The purpose of this study was to identify novel areas of genomic copy number change associated with transformation from follicular lymphoma (FL) to diffuse large B cell lymphoma (DLBL). DNA was extracted from tumour cells micro-dissected from paraffin- embedded tissue sections in 24 patients with FL and subsequent transformation to DLBL and 18 patients with de novo DLBL. Tumour DNA was compared to reference DNA using comparative genomic hybridization. Abnormalities common to all 3 groups were gains on chromosomes 4q, 5q, 7q, 11q and X and losses on 3p, 8p and 10q. Copy number changes seen in both transformed and de novo DLBL and not seen in FL were gains on 2p and losses on 1q, 15q and Xq. Gains on 2q, 6p, 7p and 17q and losses on 5p and 8q were specific to transformed DLBL cases. Gain on 12q12-14 was found in 52% of the transformed DLBL cases and was never seen in its follicular counterpart. Patterns of genomic copy number change associated with specific clinical events in NHL have been demonstrated and suggest that gains on 2q, 6p, 7p, 12q and 17q and losses on 5p and 8q may be important in the transformation from low to high-grade disease. © 2001 Cancer Research Campaign http://www.bjcancer.co
Cosmic Microwave Background Anisotropy Window Functions Revisited
The primary results of most observations of cosmic microwave background (CMB)
anisotropy are estimates of the angular power spectrum averaged through some
broad band, called band-powers. These estimates are in turn what are used to
produce constraints on cosmological parameters due to all CMB observations.
Essential to this estimation of cosmological parameters is the calculation of
the expected band-power for a given experiment, given a theoretical power
spectrum. Here we derive the "band power" window function which should be used
for this calculation, and point out that it is not equivalent to the window
function used to calculate the variance. This important distinction has been
absent from much of the literature: the variance window function is often used
as the band-power window function. We discuss the validity of this assumed
equivalence, the role of window functions for experiments that constrain the
power in {\it multiple} bands, and summarize a prescription for reporting
experimental results. The analysis methods detailed here are applied in a
companion paper to three years of data from the Medium Scale Anisotropy
Measurement.Comment: 5 pages, 1 included .eps figure, PRD in press---final published
versio
Physical Aspects of Axonemal Beating and Swimming
We discuss a two-dimensional model for the dynamics of axonemal deformations
driven by internally generated forces of molecular motors. Our model consists
of an elastic filament pair connected by active elements. We derive the dynamic
equations for this system in presence of internal forces. In the limit of small
deformations, a perturbative approach allows us to calculate filament shapes
and the tension profile. We demonstrate that periodic filament motion can be
generated via a self-organization of elastic filaments and molecular motors.
Oscillatory motion and the propagation of bending waves can occur for an
initially non-moving state via an instability termed Hopf bifurcation. Close to
this instability, the behavior of the system is shown to be independent of
microscopic details of the axoneme and the force-generating mechanism. The
oscillation frequency however does depend on properties of the molecular
motors. We calculate the oscillation frequency at the bifurcation point and
show that a large frequency range is accessible by varying the axonemal length
between 1 and 50m. We calculate the velocity of swimming of a flagellum
and discuss the effects of boundary conditions and externally applied forces on
the axonemal oscillations.Comment: 14 pages, 8 figures, REVTE
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