Mitochondrial DNA haplogroup distribution in prostate cancer cases and controls in the Korean population.

<p>The parsimonious tree on the top shows the evolutionary relationship of 22 haplogroups; capital letter-number codes denote haplogroups, all mutations are indicated by the substituted nucleotides after the number. ^aProstate cancer; ^bNormal control; Exact test <i>P</i> value (s.e.) = 0.6064±(0.0374).</p

Clinicopathological characteristics of Korean prostate cancer patients and control groups surveyed here.

*<p>Mean age±SD.</p

Analysis of association between prostate cancer risk and the mtDNA haplogroups in this study.

<p>Abbreviations: CI, confidence interval; OR, odds ratio.</p><p>Each haplogroup (hg) was first tested separately and then each phylogenetically-combined group was also tested.</p>*<p>The Fisher exact test of proportions.</p

Figure 1

<p>Y-chromosomal haplogroup distribution in prostate cancer cases and controls in the Korean population. The parsimonious tree on the top shows the evolutionary relationship of fifteen haplogroups. Nomenclature is according to the Y Chromosome Consortium <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000172#pone.0000172-Y1" target="_blank">[37]</a>. ^aProstate cancer; ^bNormal control; Exact <i>P</i> value = 0.44225±0.02442</p