7,448 research outputs found
Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells
Helicobacter pylori Infection and Halitosis – Evidence, Hypothesis, and Korean Red Ginseng to Mitigate Its Effect
Halitosis is a common and ignored condition, but in some, it is a disease-associated health problem, suggestive of overt disease conditions and hasaffected about 25–30% of world’s population, bothering nonmedical social disturbance in many people. Although two kinds, pseudohalitosis and halitophobia, are also concerned, genuine halitosis originated from the oral cavity, such as gingivitis, caries, and poor oral hygiene, in 80% and the remaining 20% are extraoral sources of halitosis, which should not be ignored because of stigmata suggestive of overt tissue dysfunctions, for instance, poor nutrition and hygiene, alcohol abuse, smoking, and systemic illness such as chronic obstructive pulmonary disease, liver cirrhosis, diabetes mellitus, and chronic renal diseases. In this chapter, Helicobacter pylori (H. pylori)–associated halitosis as one of the extragastric manifestations is introduced. Since diagnostics of halitosis includes subjective methods (examiner’s sense of smell) and objective methods (instrumental analysis), under the hypothesis of a possible relationship between H. pylori infection and objective halitosis, the real levels of volatile sulfur compounds (VSCs) in the breath showed significant correlation between VSC levels and the degree of H. pylori–associated erosive gastritis as well as gastric cancer. These findings are further validated through either measuring H2S level in gastric juices of H. pylori–infected gastritis or checking the expressions of cystathionine-γ-lyase (CSE) and cystathionine-β-synthase (CBS) responsible for H2S generation in biopsied stomach. The eradication of H. pylori significantly ameliorated halitosis, accompanied with significant reductions in gastric H2S levels (p<0.01). Korean red ginseng was very effective in either reducing H. pylori–associated H2S or alleviating halitosis in patients with H. pylori–associated chronic atrophic gastritis. Conclusively, H. pylori infection demonstrates to have an important relationship with the development of halitosis, and its eradication could possibly promote the improvement of this condition
A Study on Thermal Modeling and Heat Load Mitigation for Satellite Electronic Components
Since most of the satellite components are using various EEE (Electrical, Electronic and Electromechanical) parts, the reliability of EEE parts acts very important in the satellite system. There are many factors that influence the reliability of EEE parts in the satellite system. Excessively dissipated heat can cause the failure of EEE parts and consequently, leading to a failure of total satellite system. In this paper, the thermal modeling using nodal network was compared with that using plate modeling to find out which one is the most suitable methodology. For a comparison, KOMPSAT- 1 SAR was modeled by two different modeling and the result was discussed. There was almost no difference in the numerical results between the two modeling methods. However, while it took much more time to perform thermal analysis using the nodal network modeling method, and the debugging was more difficult in the plate modeling method when the error is occurred. The computation time was considerably reduced by developing and implementing the input file format transfer code when using nodal network modeling method. It was found that the nodal network modeling method is suitable for the complicated components, such as SAR or transponder, because of its simple debugging ability. Excessive heat load was expected on some EEE parts of SAR such as high heat-dissipated diodes, transistors, and inductors due to increased power requirements of KOMPSAT-2 satellite system. The methods for the mitigation of heat load were studied through the design change of housing or the layout change of high power parts
EFFECT OF VIBRATION APPLICATION INTO DYNAMIC LEG PRESS EXERCISE WITH EXTRA LOAD: MULTI-BODY DYNAMIC ANALYSIS
INTRODUCTION: Many studies have emphasized the importance of resistive exercise in maintaining a healthy human body, particularly in prevention of weakening of physical strength (Kostka, 2002). Recently, some of studies advocated that an application of vibration as a supplementary means in regular training was effective in encouraging physical strength (Annino et al., 2007). Aim of the current study was, therefore, to identify if an application of vibration in a resistive exercise is effective in encouraging physical strength as that in a regular training
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