17 research outputs found
Identification of 2CS-CHXT operon signature of chlorhexidine tolerance among Enterococcus faecium
OXA-carbapenemases present in clinical acinetobacter baumannii-calcoaceticus complex isolates from patients in kurdistan region, Iraq
In addition to intrinsic resistance in Acinetobacter baumannii, many different types of acquired resistance mechanisms have been reported, including the presence of VIM and IMP metallo β-lactamases and also of blaOXA-23-like and blaOXA-58-like enzymes. In the Kurdistan region of Iraq, the multiresistant A. baumannii-calcoaceticus complex is prevalent. We characterized the different mechanisms of resistance present in clinical isolates collected from different wards and different hospitals from the Kurdistan region. One hundred twenty clinical nonduplicate A. baumannii-calcoaceticus complex isolates were collected from four hospitals between January 2012 and October 2013. The identification of the isolates was confirmed by MALDI-TOF.
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Resistência antimicrobiana em Enterococcus faecalis e Enterococcus faecium isolados de carcaças de frango
Fragmentation of Protonated 2-(2-Phenylethyl)Chromones from Agarwood: The Diagnostic Role of Ion/Neutral Complexes as Reactive Intermediates
<em>In vitro </em>transfer of sulphonamide and gentamicin resistance from <em>E. coli </em>of animal origin to <em>E. coli</em> of human origin
Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: Are erm(A) pneumococcal isolates overlooked?
Transfer of sulphonamide resistance from <em>Escherichia coli </em>of animal origin to <em>E. coli</em> of human origin in the human intestine
Comparison of <em>Sul2</em> resistant gene from <em>Escherichia coli </em>isolated from animals and humans
Microarray-based detection of extended virulence and antimicrobial resistance gene profiles in phylogroup B2 Escherichia coli of human, meat and animal origin
Extra-intestinal pathogenic Escherichia coli (ExPEC) causing urinary tract infections (UTIs) most often belong to phylogenetic group B2 and stem from the patient's own faecal flora. It has been hypothesized that the external reservoir for these uropathogenic E. coli in the human intestine may be meat and food-production animals. To investigate such a connection, this study analysed an E. coli phylogroup B2 strain collection (n=161) of geographical and temporally matched isolates, published previously, from UTI patients (n=52), community-dwelling humans (n=36), imported (n=5) and Danish (n=13) broiler chicken meat, Danish broiler chickens (n=17), imported (n=3) and Danish (n=27) pork, and healthy Danish pigs (n=8). The isolates were subjected to microarray analysis for 315 virulence genes and variants and 82 antimicrobial resistance genes and variants. In total, 133 different virulence and antimicrobial resistance genes were detected in at least one UTI isolate. Between 66 and 87 of these genes were also detected in meat and animal isolates. Cluster analyses of virulence and resistance gene profiles, respectively, showed that UTI and community-dwelling human isolates most often grouped with meat and animal isolates, indicating genotypic similarity among such isolates. Furthermore, B2 isolates were detected from UTI patients and meat, with indistinguishable gene profiles. A considerable proportion of the animal and meat isolates belonged to the ExPEC pathotype. In conclusion, these findings suggest that B2 E. coli from meat and animal origin can be the source of most of the virulence and antimicrobial resistance genes detected in uropathogenic E. coli isolates and that there is a general resemblance of animal, meat and UTI E. coli based on extended gene profiling. These findings support the hypothesis of a zoonotic link between E. coli causing UTIs and E. coli from meat and animals. \ua9 2011 SGM.Peer reviewed: YesNRC publication: Ye