148 research outputs found

    SO(10) GUTs with gauge mediated supersymmetry breaking

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    We explore the phenomenology of supersymmetric SO(10) grand unified theories with gauge mediated supersymmetry breaking. We show that if SO(10) breaking proceeds through intermediate left-right symmetric gauge groups which are broken at the supersymmetry breaking scale, then perturbative unification allows the existence of only a few consistent models with very similar phenomenological consequences. We list and discuss some distinctive signatures of these theories. The most remarkable feature of the class of theories introduced here is that, unlike in models with simpler symmetry breaking chains, the allowed messenger spectrum is practically unique.Comment: 5 pages, no figures, uses REVTeX (replaced to match the version to be published in PLB: some typos corrected and a reference updated, a minor clarifying modification to the text

    Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors

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    Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde. The new compounds were fully characterized by spectroscopic techniques. All synthesized compounds exhibited high tyrosinase inhibitory behavior. The results of mushroom tyrosinase inhibition assays indicate that the 4-trifluoromethoxy derivatives have high degrees of inhibition and N,N-dimethylaniline derivatives are better for tyrosinase inhibition than 1-naphthol and 2-naphthol derivatives. All synthesized azo compounds (4a-4f) showed the most potent mushroom tyrosinase inhibition, comparable to that of Kojic acid and l-mimosine, as reference standard inhibitors. © 2013 Elsevier Ltd. All rights reserved

    Commensurate 4a04a_0 period Charge Density Modulations throughout the Bi2Sr2CaCu2O8+xBi_2Sr_2CaCu_2O_{8+x} Pseudogap Regime

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    Theories based upon strong real space (r-space) electron electron interactions have long predicted that unidirectional charge density modulations (CDM) with four unit cell (4a0a_0) periodicity should occur in the hole doped cuprate Mott insulator (MI). Experimentally, however, increasing the hole density p is reported to cause the conventionally defined wavevector QAQ_A of the CDM to evolve continuously as if driven primarily by momentum space (k-space) effects. Here we introduce phase resolved electronic structure visualization for determination of the cuprate CDM wavevector. Remarkably, this new technique reveals a virtually doping independent locking of the local CDM wavevector at Q0=2π/4a0|Q_0|=2\pi/4a_0 throughout the underdoped phase diagram of the canonical cuprate Bi2Sr2CaCu2O8Bi_2Sr_2CaCu_2O_8. These observations have significant fundamental consequences because they are orthogonal to a k-space (Fermi surface) based picture of the cuprate CDM but are consistent with strong coupling r-space based theories. Our findings imply that it is the latter that provide the intrinsic organizational principle for the cuprate CDM state

    Consistency between ARPES and STM measurements on SmB6_6

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    Strongly correlated topological surface states are promising platforms for next-generation quantum applications, but they remain elusive in real materials. The correlated Kondo insulator SmB6_6 is one of the most promising candidates, with theoretically predicted heavy Dirac surface states supported by transport and scanning tunneling microscopy (STM) experiments. However, a puzzling discrepancy appears between STM and angle-resolved photoemission (ARPES) experiments on SmB6_6. Although ARPES detects spin-textured surface states, their velocity is an order of magnitude higher than expected, while the Dirac point -- the hallmark of any topological system -- can only be inferred deep within the bulk valence band. A significant challenge is that SmB6_6 lacks a natural cleavage plane, resulting in ordered surface domains limited to 10s of nanometers. Here we use STM to show that surface band bending can shift energy features by 10s of meV between domains. Starting from our STM spectra, we simulate the full spectral function as an average over multiple domains with different surface potentials. Our simulation shows excellent agreement with ARPES data, and thus resolves the apparent discrepancy between large-area measurements that average over multiple band-shifted domains and atomically-resolved measurements within a single domain

    Bounds on R-Parity Violating Parameters from Fermion EDM's

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    We study one-loop contributions to the fermion electric dipole moments in the Minimal Supersymmetric Standard Model with explicit R-parity violating interactions. We obtain new individual bounds on R-parity violating Yukawa couplings and put more stringent limits on certain parameters than those obtained previously.Comment: 16 pages, LaTe

    Gauged Yukawa Matrix Models and 2-Dimensional Lattice Theories

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    We argue that chiral symmetry breaking in three dimensional QCD can be identified with N\'eel order in 2-dimensional quantum antiferromagnets. When operators which drive the chiral transition are added to these theories, we postulate that the resulting quantum critical behavior is in the universality class of gauged Yukawa matrix models. As a consequence, the chiral transition is typically of first order, although for a limited class of parameters it can be second order with computable critical exponents.Comment: LaTeX, 11 page

    Genomic and phenotypic analyses of diverse non-clinical Acinetobacter baumannii strains reveals strain-specific virulence and resistance capacity.

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    Acinetobacter baumannii is a critically important pathogen known for its widespread antibiotic resistance and ability to persist in hospital-associated environments. Whilst the majority of A. baumannii infections are hospital-acquired, infections from outside the hospital have been reported with high mortality. Despite this, little is known about the natural environmental reservoir(s) of A. baumannii and the virulence potential underlying non-clinical strains. Here, we report the complete genome sequences of six diverse strains isolated from environments such as river, soil, and industrial sites around the world. Phylogenetic analyses showed that four of these strains were unrelated to representative nosocomial strains and do not share a monophyletic origin, whereas two had sequence types belonging to the global clone lineages GC1 and GC2. Further, the majority of these strains harboured genes linked to virulence and stress protection in nosocomial strains. These genotypic properties correlated well with in vitro virulence phenotypic assays testing resistance to abiotic stresses, serum survival, and capsule formation. Virulence potential was confirmed in vivo, with most environmental strains able to effectively kill Galleria mellonella greater wax moth larvae. Using phenomic arrays and antibiotic resistance profiling, environmental and nosocomial strains were shown to have similar substrate utilisation patterns although environmental strains were distinctly more sensitive to antibiotics. Taken together, these features of environmental A. baumannii strains suggest the existence of a strain-specific distinct gene pools for niche specific adaptation. Furthermore, environmental strains appear to be equally virulent as contemporary nosocomial strains but remain largely antibiotic sensitive
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