Wild Type Mice, Number of Gaps per square mm (Standard versus Enriched Housing)

<p>No significant difference (Statistical significance obtained using Mann-Whitney Rank Sum Test)</p

Figure 3

<p>Electron micrographs of transverse ultra-thin sections of aortas from wild-type mice housed in a standard cage (panel A) and an enriched cage (panel B).</p

Standard Housing (four per cage), Number of Gaps per square mm (Wild Type Mice versus Fibulin-4^+/− Mice)

<p>Statistical significance, p = 0.006 (Statistical significance obtained using Mann-Whitney Rank Sum Test)</p

Fibulin-4^+/− Mice, Number of Gaps per square mm (Standard versus Enriched Housing)

<p>Statistical significance, p = 0.016 (Statistical significance obtained using Mann-Whitney Rank Sum Test)</p

Enriched Housing (two per cage), Number of Gaps per square mm (Wild Type Mice versus Fibulin-4^+/− Mice)

<p>Statistical significance, p = 0.008 (Statistical significance obtained using Mann-Whitney Rank Sum Test)</p

Figure 2

<p>Electron micrographs of transverse ultra-thin sections of aortas from fibulin-4^+/− mice housed in a standard cage (panel A) and an enriched cage (panel B).</p