1,844 research outputs found
LAGOVirtual: A Collaborative Environment for the Large Aperture GRB Observatory
We present the LAGOVirtual Project: an ongoing project to develop platform to
collaborate in the Large Aperture GRB Observatory (LAGO). This continental-wide
observatory is devised to detect high energy (around 100 GeV) component of
Gamma Ray Bursts, by using the single particle technique in arrays of Water
Cherenkov Detectors (WCD) at high mountain sites (Chacaltaya, Bolivia, 5300 m
a.s.l., Pico Espejo, Venezuela, 4750 m a.s.l., Sierra Negra, Mexico, 4650 m
a.s.l). This platform will allow LAGO collaboration to share data, and computer
resources through its different sites. This environment has the possibility to
generate synthetic data by simulating the showers through AIRES application and
to store/preserve distributed data files collected by the WCD at the LAGO
sites. The present article concerns the implementation of a prototype of
LAGO-DR adapting DSpace, with a hierarchical structure (i.e. country,
institution, followed by collections that contain the metadata and data files),
for the captured/simulated data. This structure was generated by using the
community, sub-community, collection, item model; available at the DSpace
software. Each member institution-country of the project has the appropriate
permissions on the system to publish information (descriptive metadata and
associated data files). The platform can also associate multiple files to each
item of data (data from the instruments, graphics, postprocessed-data, etc.).Comment: Second EELA-2 Conference Choroni, Venezuela, November 25th to 27th
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Production Technology and Competitiveness In the Hungarian Manufacturing Industry
Following the big transformations of the 1990s, enterprise structure and technological level seem to
have become stabilised in Hungary. Under these circumstances it is especially interesting to identify
the elements responsible for competitiveness in general, and the role technology plays in development
in particular, according to managers experienced in production and marketing. This empirical
study – based on in-depth interviews and field research – summarises characteristics of the technological
level in the sectors examined, role of technology and labour in production, effects of foreign
direct investment, relations between competition and firm-level factors determining competitiveness,
and concludes by summing up those most frequently mentioned proposals that should be incorporated
into economic policy according to managers. Main findings indicate that more qualified,
more intensive and cheaper labour can be substituted for high technology. The competitiveness of an
enterprise is not determined by technology alone, but rather by a combination of technology, the parameters
of available labour and the costs of investment increasing productivity. The insufficiency
of inter-company relations, together with a shortage of available assets necessary for investment
constitute the major threat undermining the competitiveness of enterprises in present-day Hungary
Near-thermal equilibrium with Tsallis distributions in heavy ion collisions
Hadron yields in high energy heavy ion collisions have been fitted and
reproduced by thermal models using standard statistical distributions. These
models give insight into the freeze-out conditions at varying beam energies. In
this paper we investigate changes to this analysis when the statistical
distributions are replaced by Tsallis distributions for hadrons. We investigate
the appearance of near-thermal equilibrium state at SPS and RHIC energies. We
obtain better fits with smaller chi^2 for the same hadron data, as applied
earlier in the thermal fits for SPS energies but not for RHIC energies. This
result indicates that at RHIC energies the final state is very well described
by a single freeze-out temperature with very little room for fluctuations.Comment: 8 pages, 6 figure
VHMPID: a new detector for the ALICE experiment at LHC
This article presents the basic idea of VHMPID, an upgrade detector for the
ALICE experiment at LHC, CERN. The main goal of this detector is to extend the
particle identification capabilities of ALICE to give more insight into the
evolution of the hot and dense matter created in Pb-Pb collisions. Starting
from the physics motivations and working principles the challenges and current
status of development is detailed.Comment: 4 pages, 6 figures. To be published in EPJ Web of Conference
Pre-Excitation Studies for Rubidium-Plasma Generation
The key element in the Proton-Driven-Plasma-Wake-Field-Accelerator (AWAKE)
project is the generation of highly uniform plasma from Rubidium vapor. The
standard way to achieve full ionization is to use high power laser which can
assure the over-barrier-ionization (OBI) along the 10 meters long active
region. The Wigner-team in Budapest is investigating an alternative way of
uniform plasma generation. The proposed Resonance Enhanced Multi Photon
Ionization (REMPI) scheme probably can be realized by much less laser power. In
the following the resonant pre-excitations of the Rb atoms are investigated,
theoretically and the status report about the preparatory work on the
experiment are presented.Comment: 8 pages, 6 figures, submitted to Nucl. Inst. and Meth. in Phys. Res.
The high voltage system for the novel MPGD-based photon detectors of COMPASS RICH-1
The architecture of the novel MPGD-based photon detectors of COMPASS RICH-1
consists in a large-size hybrid MPGD multilayer layout combining two layers of
Thick-GEMs and a bulk resistive MICROMEGAS. Concerning biasing voltage, the
Thick-GEMs are segmented in order to reduce the energy released in case of
occasional discharges, while the MICROMEGAS anode is segmented in pads
individually biased at positive voltage, while the micromesh is grounded. In
total, there are ten different electrode types and more than 20000 electrodes
supplied by more than 100 HV channels. Commercial power supply units are used.
The original elements of the power supply system are the architecture of the
voltage distribution net, the compensation, by voltage adjustment, of the
effects of pressure and temperature variation affecting the detector gain and a
sophisticated control software, which allows to protect the detectors against
errors by the operator, to monitor and log voltages and current at 1 Hz rate
and to automatically react to detector misbehaviors. The HV system and its
performance are described in detail as well as the electrical stability of the
detector during the operation at COMPASS.Comment: 5th international conference on Micro-Pattern Gas Detectors
(MPGD2017),presentation by Silvia Dalla Torr
Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model.
Abstract
BACKGROUND:
The aim of this study was to examine the effects of the hyperandrogenic state in dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS), the vascular responses to different vasoactive agents, and the modulatory role of vitamin D3.
METHODS:
APCOS model was induced by DHT application in 20 female Wistar rats. Ten of the DHT treated rats simultaneously received calcitriol treatment. After 10 weeks, myographs were used to test the reactivity of isolated thoracic aortic rings to norepinephrine and acetylcholine. Thereafter, the vascular rings were incubated with the NO-synthase blocker (nitro-L-arginine methyl ester) or the cyclooxygenase inhibitor (indomethacin) for 20 min, and the effects of norepinephrine and acetylcholine were re-evaluated.
RESULTS:
Norepinephrine-induced vasoconstriction was enhanced after DHT treatment, but this effect was attenuated by calcitriol administration. Vasorelaxation of DHT-treated thoracic aortic rings was impaired, but this could be partly reversed by calcitriol application. Impaired NO-dependent vasorelaxation in DHT-treated animals was mostly reversed by concomitant calcitriol administration, but this effect was diminished by prostanoid-dependent vasoconstriction.
CONCLUSIONS:
These studies show that the enhanced sensitivity to vasoconstrictors and impaired NO-dependent vasorelaxation in hyperandrogenic PCOS rats could be partially reversed by calcitriol treatment
Remote physiological monitoring: Clinical, financial, and behavioral outcomes in a heart failure population
This article reports on the outcomes associated with remote physiological monitoring (RPM) conducted as part of a heart failure disease management program. Claims data, medical records, data transmission records, and survey results for 91 individuals ages 50–92 (mean 74 years) successfully completing a heart failure RPM program were analyzed for time periods before, during, and after the monitoring intervention. The program was associated with significant reductions in per member per month costs and emergency room and hospital utilization. More detailed analyses were performed for specific gender and age subgroups. Participant surveys indicated high levels of satisfaction, and improvements in self-perceived health status, self-efficacy, and self-management behaviors. This study is the first to assess the impact of a RPM program following removal of the monitoring equipment. The results indicate that RPM, as a component of a traditional disease management program, has a sustained, beneficial effect on participants’ lifestyles after the monitoring period has ended
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