Beam Alignment of Scanning Microbeam PIXE Analysis System in NIRS Electrostatic Accelerator Facility

The scanning microbeam PIXE(Particle Induced X-ray Emission) analysis allows identifying the several surface elements and taking the high-resolution elemental maps of the specimen at a time, by using the narrow beam downed the size to 1um and the maximum scanning area of 2mm square. We are applying this system to the elements and the structure analysis for bio-cells and environmental specimens. The most important procedure to obtain the high-resolution maps is increasing spatial resolution of the micorbeam. We diagnose the resolution by using Scanning Transmission Ion Microscopy (STIM) and PIXE images of the 12.5um pitch copper mesh. In this workshop, we introduce our experiences of the alignment of the microbeam system.The 4th Workshop on Accelerator Operatio

Diagnosis of Spatial Resolution for Microbeam Scanning PIXE using STIM Method and CR-39 Track Detector in PASTA

In PIXE analysis system and Tandem Accelerator facility ( PASTA ) of NIRS, we are using Scanning Transmission Ion Microscopy (STIM) method and solid track detector to diagnose the spatial resolution of scanning microbeam PIXE analysis system. These methods are widely used by many microbeam facilities

USER-FRIENDLY DROPLET-PIXE SYSTEM FOR QUANTITATIVE ANALYSIS

Workshop on Accelerator Operation 200

Development of Droplet-PIXE system for Environmental Monitoring Samples

Behaviour of radionuclides in the environment and organisms has been investigated to evaluate the radiation effect on human using stable isotopes using PIXE analysis at the PASTA facilities in the NIRS. Since some of the environmental monitoring samples are in the liquid state, pre-treatment of the samples such as filtration, drying and solidification are necessary prior to the PIXE analysis. During sample preparation process, there may be loss of element due to sublimation or evaporation that must be taken care for quantitative analysis. To avoid such problems, we have developed a suitable dropletPIXE system. It is based on the following points,(i) development of equipment with a good stability to supply a droplet of good reproducibility, (ii) optimisation of all equipments that includes a stable beam line (proton, 2.8MeV) and (iii) to evaluate irradiation dose for quantitative analysis. It will be advantageous to many researchers since it is very simple and save time during the sample preparation. However, there are some disadvantages in the detection range compared to conventional PIXE. The droplet-PIXE system has been applied to a few case studies. Limits of detection with or without any chemical preparation and its superiority or advantages over other PIXE system will be discussed in this paper. Application of the droplet-PIXE system can be expanded in future to other possibilities.5th International Symposium on BioPIX

Introduction of Micro-beam System in NIRS

National Institute of Radiological Sciences (NIRS) was established in 1957 as a special research institute for research and medical application of radiation, attached to the Science and Technology Agency of Japan. In 1961, NIRS started to use a Van de Graff accelerator (Model KN3000, High Voltage Engineering) for PIXE (Particle Induced X-ray Emission) analysis that was operated as a device for pre-tumor therapy with neutron and finally discarded in 1997. In March 1999, an electrostatic accelerator, HVEE Tandetron, was installed in the Electrostatic Accelerator Building for PIXE analysis. PIXE analysis is a trace analytical method, which has the advantage of simultaneous determination of elemental concentrations in a small specimen without any chemical separation by measuring characteristic X-rays of elements induced by accelerated charged nuclear particles such as protons. [1] In this paper, characteristics of the PIXE system and the new microbeam irradiation facility, Single Particle Irradiation System to Cell (SPICE), which is introduced to our Tandem accelerator are described.The 3rd International Symposium on Future Medical Engineering based on BIO-nanotechnolog