Feminism, Religion, and Work in the United States

Feminism in the contemporary United States is a diverse field of thought with several strains of ideological leanings, including liberal, neoliberal, and the contested conservative feminism. Each is uniquely situated in the American context due to the heavy influence of American values and culture-specific definitions of justice, success, and progress. Entrenched in the Western conceptions of secularism and advancement, “modern” feminism in the United States prides itself as the example of peak progressivism, yet does so without critically engaging with its definition of modernity or secularism. In particular, the relationship between religion and feminism is complicated in the U.S., with intersections between the ideas of secularism, justice, and tradition resulting in conflicts between religious and secular understandings of feminism. This paper draws on the results from interviews with 6 college-age and 2 Gen-X subjects of different religions, and analyzes the state of the contemporary understanding of the relationship between feminism, religion, and the valuation of breadwinning versus caregiving in the U.S. The interviews point to a widespread liberal feminist outlook that prioritizes social justice and a choice-based approach to work-life balance, and highlights the divides between those who see feminism as naturally religious, those who are caught in the entanglement of patriarchy and religion, and those who see feminism as a secular endeavor

DNA Display II. Genetic Manipulation of Combinatorial Chemistry Libraries for Small-Molecule Evolution

Biological in vitro selection techniques, such as RNA aptamer methods and mRNA display, have proven to be powerful approaches for engineering molecules with novel functions. These techniques are based on iterative amplification of biopolymer libraries, interposed by selection for a desired functional property. Rare, promising compounds are enriched over multiple generations of a constantly replicating molecular population, and subsequently identified. The restriction of such methods to DNA, RNA, and polypeptides precludes their use for small-molecule discovery. To overcome this limitation, we have directed the synthesis of combinatorial chemistry libraries with DNA “genes,” making possible iterative amplification of a nonbiological molecular species. By differential hybridization during the course of a traditional split-and-pool combinatorial synthesis, the DNA sequence of each gene is read out and translated into a unique small-molecule structure. This “chemical translation” provides practical access to synthetic compound populations 1 million-fold more complex than state-of-the-art combinatorial libraries. We carried out an in vitro selection experiment (iterated chemical translation, selection, and amplification) on a library of 10(6) nonnatural peptides. The library converged over three generations to a high-affinity protein ligand. The ability to genetically encode diverse classes of synthetic transformations enables the in vitro selection and potential evolution of an essentially limitless collection of compound families, opening new avenues to drug discovery, catalyst design, and the development of a materials science “biology.

Naturaliste plateau: constraints on the timing and evolution of the Kerguelen Large Igneous Province and its role in Gondwana breakup

Volcanism associated with the Kerguelen Large Igneous Province is found scattered in southwestern Australia (the ca 136 to ca 130 Ma Bunbury Basalts, and ca 124 Ma Wallaby Plateau), India (ca 118 Ma Rajmahal Traps and Cona Basalts), and Tibet (the ca 132 Ma Comei Basalts), but apart from the ∼70 000 km2 Wallaby Plateau, these examples are spatially and volumetrically minor. Here, we report dredge, geochronological and geochemical results from the ∼90 000 km2 Naturaliste Plateau, located ∼170 to ∼500 km southwest of Australia. Dredged lavas and intrusive rocks range from mafic to felsic compositions, and prior geophysical analyses indicate these units comprise much of the plateau substrate. 40Ar/39Ar plagioclase ages from mafic units and U–Pb zircon ages from silicic rocks indicate magmatic emplacement from 130.6 ± 1.2 to 129.4 ± 1.3 Ma for mafic rocks and 131.8 ± 3.9 to 128.2 ± 2.3 Ma for silicic rocks (2σ). These Cretaceous Naturaliste magmas incorporated a significant component of continental crust, with relatively high 87Sr/86Sr (up to 0.78), high 207Pb/204 Pb ratios (15.5–15.6), low 143Nd/144Nd (0.511–0.512) and primitive-mantle normalised Th/Nb of 11.3 and La/Nb of 3.97. These geochemical results are consistent with the plateau being underlain by continental basement, as indicated by prior interpretations of seismic and gravity data, corroborated by dredging of Mesoproterozoic granites and gneisses on the southern plateau flank. The Cretaceous Naturaliste Plateau igneous rocks have signatures indicative of extraction from a depleted mantle, with trace-element and isotopic values that overlap with Kerguelen Plateau lavas reflect crustal contamination. Our chemical and geochronological results therefore show the Naturaliste Plateau contains evidence of an extensive igneous event representing some of the earliest voluminous Kerguelen hotspot magmas. Prior work reports that contemporaneous correlative volcanic sequences underlie the nearby Mentelle Basin, and the Enderby Basin and Princess Elizabeth Trough in the Antarctic. When combined, the igneous rocks in the Naturaliste, Mentelle, Wallaby, Enderby, Princess Elizabeth, Bunbury and Comei-Cona areas form a 136–124 Ma Large Igneous Province covering >244 000 km2

Teaching reading through imaginative play situations in grades one and two

Thesis (Ed.M.)--Boston Universit

Comment on: Role of Intermittency in Urban Development: A Model of Large-Scale City Formation

Comment to D.H. Zanette and S.C. Manrubia, Phys. Rev. Lett. 79, 523 (1997).Comment: 1 page no figure

Casper Is a FADD- and Caspase-Related Inducer of Apoptosis

AbstractCaspases are cysteine proteases that play a central role in apoptosis. Caspase-8 may be the first enzyme of the proteolytic cascade activated by the Fas ligand and tumor necrosis factor (TNF). Caspase-8 is recruited to Fas and TNF receptor-1 (TNF-R1) through interaction of its prodomain with the death effector domain (DED) of the receptor-associating FADD. Here we describe a novel 55 kDa protein, Casper, that has sequence similarity to caspase-8 throughout its length. However, Casper is not a caspase since it lacks several conserved amino acids found in all caspases. Casper interacts with FADD, caspase-8, caspase-3, TRAF1, and TRAF2 through distinct domains. When overexpressed in mammalian cells, Casper potently induces apoptosis. A C-terminal deletion mutant of Casper inhibits TNF- and Fas-induced cell death, suggesting that Casper is involved in these apoptotic pathways

Non-perturbative renormalization of the KPZ growth dynamics

We introduce a non-perturbative renormalization approach which identifies stable fixed points in any dimension for the Kardar-Parisi-Zhang dynamics of rough surfaces. The usual limitations of real space methods to deal with anisotropic (self-affine) scaling are overcome with an indirect functional renormalization. The roughness exponent $\alpha$ is computed for dimensions $d=1$ to 8 and it results to be in very good agreement with the available simulations. No evidence is found for an upper critical dimension. We discuss how the present approach can be extended to other self-affine problems.Comment: 4 pages, 2 figures. To appear in Phys. Rev. Let

Topological relaxation of entangled flux lattices: Single vs collective line dynamics

A symbolic language allowing to solve statistical problems for the systems with nonabelian braid-like topology in 2+1 dimensions is developed. The approach is based on the similarity between growing braid and "heap of colored pieces". As an application, the problem of a vortex glass transition in high-T_c superconductors is re-examined on microscopic levelComment: 4 pages (revtex), 4 figure