Designing a Tablet-based Intervention to Support Self-checking for Melanoma

Postprin

Quantifying the thermal Sunyaev–Zel’dovich effect and excess millimetre emission in quasar environments

In this paper, we probe the hot, post-shock gas component of quasar-driven winds through the thermal Sunyaev–Zel’dovich (tSZ) effect. Combining data sets from the Atacama Cosmology Telescope, the Herschel Space Observatory, and the Very Large Array, we measure average spectral energy distributions of 109 829 optically selected, radio quiet quasars from 1.4 to 3000 GHz in six redshift bins between 0.3 1.91, we measure the tSZ effect at 3.8σ significance with an amplitude corresponding to a total thermal energy of 3.1 × 10⁶⁰ erg. If this energy is due to virialized gas, then our measurement implies quasar host halo masses are ∼6 × 10¹² h⁻¹ M⊙. Alternatively, if the host dark matter halo masses are ∼2 × 10¹² h⁻¹ M⊙ as some measurements suggest, then we measure a >90 per cent excess in the thermal energy over that expected due to virialization. If the measured SZ effect is primarily due to hot bubbles from quasar-driven winds, we find that (5^(+1.2)_(−1.3) per cent of the quasar bolometric luminosity couples to the intergalactic medium over a fiducial quasar lifetime of 100 Myr. An additional source of tSZ may be correlated structure, and further work is required to separate the contributions. At z ≤ 1.91, we detect emission at 95 and 148 GHz that is in excess of thermal dust and optically thin synchrotron emission. We investigate potential sources of this excess emission, finding that CO line emission and an additional optically thick synchrotron component are the most viable candidates

Responding to Child and Adolescent to Parent Violence and Abuse from a Distance: Remote Delivery of Interventions during Covid-19

Working with families living with child and adolescent-to-parent violence raises a number of challenges which were compounded during the Covid-19 pandemic. In this article, UK umbrella organisation ‘Respect’ is used as a case study to explore how 10 practitioners navigated social, emotional, and safeguarding concerns that occurred when transitioning to remote working. Engagement with children and young people proved difficult, especially for those with special education needs and/or disabilities. However, parental engagement with services increased. Practitioners were quick to adapt to the changing landscape of remote working; continually adapting their practice to otherwise unforeseen safeguarding and/or practical challenges

Radically open dialectical behavior therapy: Social signaling, transdiagnostic utility and current evidence

At the core of an overcontrolled personality and coping style is a tendency to have too much self-control, exhibiting as behavioral and cognitive inflexibility, high inhibition of emotion, high detail-focused processing and perfectionism, and a lack of social connectedness. Overcontrol underlies a wide variety of psychiatric illnesses and as such, an innovative transdiagnostic therapy called Radically Open Dialectical Behavior Therapy (RO DBT) has been developed to treat disorders characterized by overcontrol. RO DBT targets maladaptive social signaling in order to help individuals rejoin the tribe, hypothesizing that increasing social connectedness by means of targeting social signaling is the central mechanism of change in treatment. Because RO DBT is used for individuals with an overcontrolled personality style, rather than individual disordered symptoms, it can be used transdiagnostically across a range of comorbid disorders, including treatment-resistant depression and anxiety, anorexia nervosa, and personality disorders such as obsessive-compulsive personality disorder. The current article introduces this novel treatment approach and discusses its emphasis on social signaling and its transdiagnostic nature. We then provide the first review of existing literature testing the efficacy of RO DBT across clinical populations, discuss issues related to assessment of overcontrol, and speculate on future directions for this novel therapy

Is non-therapeutic aspirin use in children a problem in South Africa?

Background. Aspirin should not be used in children except for specific therapeutic reasons. We report on a severely ill infant who had ingested aspirin contained in a traditional medicine and review 21 other patients with pre-admission non-therapeutic salicylate exposure. Objectives and methods. We reviewed laboratory, clinical and poisons unit records to determine how many children were admitted to our hospital over an 18-month period with evidence of salicylate ingestion not prescribed for therapeutic reasons. We determined the source of the salicylate, elapsed time between ingestion and laboratory assay, morbidity and mortality and final diagnosis. Results. Twenty-one children meeting our criteria, including 9 under 6 months of age, were admitted during this period. The most prevalent source of salicylate was over-the-counter (OTC) aspirin, but some had reportedly only been given traditional medicines. Nineteen were seriously ill, 4 died and 3 had severe brain injury. Two, initially diagnosed with Reye’s syndrome, probably had inherited metabolic disorders. Only 2 patients had salicylate levels that at the time of measurement are normally considered toxic; however, the literature suggests that lower levels may exacerbate illness severity in young children. Conclusions. We found inappropriate use of OTC aspirin in children that requires explanation. There may be policy implications for the content and presentation of patient information; the incorporation of pharmaceuticals in traditional medicines merits further study. Salicylate toxicity should be considered in children with unexplained metabolic acidosis out of keeping with the severity of their acute illness

Tully’s the fashion : Ciceronian fame in Frances Burney’s Cecilia

Across a festively lit drawing room at a fashionable London masquerade, the eponymous heroine of Frances Burney’s Cecilia (1782) catches sight of a man dressed in Ciceronian costume. She identifies him as the famous Roman statesman by his toga and “consular dignity.” At first glance, this brief scene is utterly forgettable because, as Peter Gay has noted, Cicero today is “at best an interesting politician and a master of a certain Latin style; at worst he is a bore or an unknown.” A closer look, however, reveals not only Burney’s deep awareness of Cicero’s significance as a “culture hero” but also her and her contemporaries’ complex relationship with his legacy. By the time of Cecilia’s publication, Cicero is no longer simply the purview of pedants and politicians but is famous to a wider London public. The popular desire to be like Tully, as he was frequently and affectionately referred to during this period, newly manifested itself in material culture, as it had become the height of fashion for his name and face to appear not only in books but also on jewelry, clothing, shop signs, and home décor. It was also during this era that Cicero’s character came under scrutiny: readers had begun to notice that Cicero’s public persona in his orations and treatises was far more virtuous than how he appears in his private correspondence. As Burney’s portrait of the masquerader reveals, her own attitude towards Cicero’s fame was equally complex: while she shared her culture’s admiration for Tully, she had misgivings about those like the Ciceronian Frenchman for whom that emulation was an affectation and an opportunity for celebrity mongering. I argue that Burney exposes her society’s affectation of Ciceronian virtue, an affectation that mirrors Cicero’s own hypocritical self-fashioning. By presenting the reader with a heroine who, like Cicero, strives for virtue and is ambitious of the fame virtue enables, the novel can be seen as a meditation on the nature of ambition itself and whether, if even those who seem to understand virtue best are undone by their desire for fame, ambition and virtue can exist simultaneously.Englis

An ngVLA Wide Area AGN Survey

The next generation Very Large Array (ngVLA) will have unprecedented sensitivities and mapping speeds at $1-8$ GHz. We discuss how the active galactic nuclei (AGN) community can benefit from a wide-area, medium depth ngVLA survey. We propose a 10 deg$^2$ survey in the Stripe 82 field using the 8 GHz band with an rms depth of $1\,\mu$Jy beam$^{-1}$. We will detect $\sim$130,000 galaxies, including radio-quiet AGN out to $z\sim7$. We can measure the luminosity and space density evolution of radio-quiet and radio-loud AGN. We can also measure AGN evolution through clustering of both populations using cross-correlation functions. A wide area ngVLA survey will benefit from existing multiwavelength AGN populations, particularly in the Stripe 82 field, as well as new information from next-generation optical and infrared survey instruments such as LSST and WFIRST.Comment: ngVLA Science Use Case to appear in the ngVLA Science Book (http://ngvla.nrao.edu/page/scibook