Effect of sinusoidal injection velocity on miscible viscous fingering of a finite sample: Nonlinear simulation

The effect of a sinusoidal injection on the fingering instability in a miscible displacement in the application of liquid chromatography, pollutant contamination in aquifers, etc., is investigated. The injection velocity, U(t) is characterized by its amplitude of Γ and time-period of T. The solute transport, flow in porous media, and mass conservation in a two-dimensional porous media is modeled by the convection-diffusion equation, Darcy's equation, and the continuity equation, respectively. The numerical simulation is performed in COMSOL Multiphysics utilizing a finite-element based approach. The fingering dynamics for various time-period have been studied for two scenarios namely, injection-extraction (Γ>1) and extraction-injection (Γ1, whereas for Γ0 the rare interface becomes unstable, while for R1,R=2 till the deformed rare interface interact with diffusive frontal interface. The average diffusive forces are significant for Γ<−1,R=−2 which can be helpful in separation of chemicals in chromatography. This study therefore provided new insights into the role of alternate injection-extraction injections in altering the fingering dynamics of the miscible sample

Potential impact of various surface ligands on the cellular uptake and biodistribution characteristics of red, green, and blue emitting Cu nanoclusters

Surface functionalization has a prominent influence on tuning/manipulating the physicochemical properties of nanometer scaled materials. Ultrasmall sized nanoclusters with very few atoms have received enormous attention due to their bright fluorescence, biocompatibility, lower toxicity, good colloidal stability and strong photostability. These properties make them suitable for diagnostic applications. In this work, we intend to study the effect of surface functional ligands on their biodistribution both in vitro and in vivo organelle systems for bioimaging applications.Published versionS. C. acknowledges the financial support from University Grant Commission-Department of Atomic Energy (UGC-DAE) Consortium for Scientific Research, (UGC-DAE-CRS/2021-22/02/513) and Science and Engineering Research Board (SERB) under State University Research Excellence (SUR/2022/001424)