910 research outputs found

    Is a birth month dependence of human longevity influenced by half yearly changes in geomagnetics?

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    About-daily and about-yearly variations in organisms are commonly viewed as evolutionary adaptations to changes in the proximate environmental temperature and illumination. There is now ample evidence that a much broader time structure (chronome), long known to characterize the environment, is built into biological variables, from the level of an ecological niche revealed by demographic statistics to that of molecular genetics. While a molecular basis has been established for circadian rhythms, indirect evidence for some endogenicity had long been available by the persistence of rhythms with a period differing from the environmental cycle under constant conditions (free-running) (1, 2). Natural environmental factors have also been shown to play a critical role, notably in terms of synchronizing built-in rhythms (1-3). As reviewed elsewhere (4), non-photic as well as photic effects of the sun may play a role in shaping the element of multifrequency rhythms currently, and may have done so in the past, resulting in even broader chronomes with added elements of chaos and trends (4, 5). Non-photic signatures include, with the biological week (5), the about 10.5-year solar activity cycle, the about 21.0-year Hale bipolarity variation, and a prominent about half-year rhythm peaking at the equinoxes. This natural physical half-year characterizes various indices of geomagnetic activity (6-15) and may relate to the tilt angle of the earth's dipole axis toward and away from the sun, which reportedly is not constant according to Robert L. McPherron. It is particularly prominent when analyzed in Kp (5, 16, 17) by the population-mean cosinor method (18, 19)

    Биологические ритмы, экология и стресс. (По материалам международного конгресса "Здоровье и образование в XXI веке. Концепции болезней цивилизации", РУДН, 2007)

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    Time, in relativistic terms in the context of the speed of light, depends not only on the speed of an observer as a whole. Several different time scales within an observer also relate differently to cycles in the cosmos, all of them assessed by spectral peaks with non-zero amplitudes. Thus, in many physiological, psychological, sociological, epidemiological and physical environmental variables, an inferential statistical transdisciplinary array of spectra unfolds, with reciprocal cycles as components with overlapping 95% confidence intervals in ever broader and diverse chronomes (time structures) that underlie the genetics of an evolving biosphere, representing a phylogenetic memory, and accumulating an as-yet fragile noosphere, to be recognized by its interactions with its cosmos, to be rendered compatible with human survival.Представление о времени неразрывно связано с Космосом и процессами, происходящими во Вселенной. Цикличность изменений характерна для подавляющего большинства физиологических, психологических, социологических и экологических процессов. Следовательно, изучение явлений, связанных с феноменом времени, может рассматриваться только в рамках междисциплинарной науки, интегрально описывающей структуру времени (хрономику), науку, фундаментом которой является генетика развивающейся биосферы. Человек, созидающий еще очень хрупкую ноосферу, прямо зависит от филогенетической памяти о своем космическом происхождении (С.М. Чибисов, Ф. Халберг, В.А. Фролов)

    A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion

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    The mechanisms by which organisms adapt their growth according to the availability of oxygen are incompletely understood. Here the authors identify the D rosophila fat body as a tissue regulating growth in response to oxygen sensing via a mechanism involving Hph inhibition, HIF1-a activation and insulin secretion
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