308 research outputs found

    Polymer Scaffolds for Small-Diameter Vascular Tissue Engineering

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    To better engineer small-diameter blood vessels, a few types of novel scaffolds are fabricated from biodegradable poly( L -lactic acid) (PLLA) by means of thermally induced phase-separation (TIPS) techniques. By utilizing the differences in thermal conductivities of the mold materials and using benzene as the solvent scaffolds with oriented gradient microtubular structures in the axial or radial direction can be created. The porosity, tubular size, and the orientational direction of the microtubules can be controlled by the polymer concentration, the TIPS temperature, and by utilizing materials of different thermal conductivities. These gradient microtubular structures facilitate cell seeding and mass transfer for cell growth and function. Nanofibrous scaffolds with an oriented and interconnected microtubular pore network are also developed by a one-step TIPS method using a benzene/tetrahydrofuran mixture as the solvent without the need for porogen materials. The structural features of such scaffolds can be conveniently adjusted by varying the solvent ratio, phase-separation temperature, and polymer concentration to mimic the nanofibrous features of an extracellular matrix. These scaffolds were fabricated for the tissue engineering of small-diameter blood vessels by utilizing their advantageous structural features to facilitate blood-vessel regeneration.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78073/1/2833_ftp.pd

    Zero-Shot Rumor Detection with Propagation Structure via Prompt Learning

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    The spread of rumors along with breaking events seriously hinders the truth in the era of social media. Previous studies reveal that due to the lack of annotated resources, rumors presented in minority languages are hard to be detected. Furthermore, the unforeseen breaking events not involved in yesterday's news exacerbate the scarcity of data resources. In this work, we propose a novel zero-shot framework based on prompt learning to detect rumors falling in different domains or presented in different languages. More specifically, we firstly represent rumor circulated on social media as diverse propagation threads, then design a hierarchical prompt encoding mechanism to learn language-agnostic contextual representations for both prompts and rumor data. To further enhance domain adaptation, we model the domain-invariant structural features from the propagation threads, to incorporate structural position representations of influential community response. In addition, a new virtual response augmentation method is used to improve model training. Extensive experiments conducted on three real-world datasets demonstrate that our proposed model achieves much better performance than state-of-the-art methods and exhibits a superior capacity for detecting rumors at early stages.Comment: AAAI 202

    Hopf Bifurcation Analysis for the Modified Rayleigh Price Model with Time Delay

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    This paper mainly modifies and further develops the Reyleigh price model. By modifying the basic Reyleigh model, we can more accurately illustrate the economic phenomena with price varying. First, we research the dynamics of the modified Reyleigh model with time delay. By employing the normal form theory and center manifold theory, we obtain some testable results on these issues. The conclusion confirms that a Hopf bifurcation occurs due to the existence of stability switches when the delay varies. Finally, some numerical simulations are given to illustrate the effectiveness of our results

    catena-Poly[[[diaqua­iron(II)]-μ-pyrazine-2,3-dicarboxyl­ato] dihydrate]

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    The crystal structure of the title compound, {[Fe(C6H2N2O4)(H2O)2]·2H2O}n, was synthesized by a diffusion method. It has a one-dimensional polymeric chain structure and the chains are further connected into a three-dimensional structure by hydrogen bonds. The FeII ion has a distorted octa­hedral coordination environment, with two N and two O atoms from the pyrazine-2,3-dicarboxyl­ate ligands in the equatorial plane and with two water mol­ecules in axial positions. The Fe atom lies on a crystallographic centre of symmetry and a twofold rotation axis passes through the pyrazine ring

    Effidit: Your AI Writing Assistant

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    In this technical report, we introduce Effidit (Efficient and Intelligent Editing), a digital writing assistant that facilitates users to write higher-quality text more efficiently by using artificial intelligence (AI) technologies. Previous writing assistants typically provide the function of error checking (to detect and correct spelling and grammatical errors) and limited text-rewriting functionality. With the emergence of large-scale neural language models, some systems support automatically completing a sentence or a paragraph. In Effidit, we significantly expand the capacities of a writing assistant by providing functions in five categories: text completion, error checking, text polishing, keywords to sentences (K2S), and cloud input methods (cloud IME). In the text completion category, Effidit supports generation-based sentence completion, retrieval-based sentence completion, and phrase completion. In contrast, many other writing assistants so far only provide one or two of the three functions. For text polishing, we have three functions: (context-aware) phrase polishing, sentence paraphrasing, and sentence expansion, whereas many other writing assistants often support one or two functions in this category. The main contents of this report include major modules of Effidit, methods for implementing these modules, and evaluation results of some key methods.Comment: Technical report for Effidit. arXiv admin note: text overlap with arXiv:2202.0641

    Electrohydraulic lithotripsy through endoscopic retrograde cholangiopancreatography combined with SpyGlass in the treatment of complex pancreatic duct stones: A case report and literature review

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    The incidence of pancreatic duct stones (PDS) is less than 1%. After the formation of stones, the lumen of the pancreatic duct is blocked, and the pancreatic juice cannot be discharged smoothly, resulting in the impairment of the internal and external secretions of the pancreas. Several national guidelines now recommend endoscopic retrograde cholangiopancreatography (ERCP) as the treatment for PDS. The emergence of SpyGlass makes it possible to visualize the ERCP blind area of the pancreatic system directly. Electrohydraulic lithotripsy (EHL) under SpyGlass can crush large and pressure-resistant stones into smaller fragments, significantly improving the success of the endoscopic treatment of large stones. Here, we report a patient presented with acute alcohol-associated pancreatitis, found to have PDS on imaging, who underwent ERCP combined with SpyGlass (EHL), avoiding surgery, reducing trauma, and being discharged from the hospital with a rapid recovery. Therefore, endoscopic therapy is effective and safe for PDS patients. The combination therapy of this patient is the first use of SpyGlass for PDS in our centre, which marks a new stage in the application of endoscopic therapy for pancreatic diseases
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