117 research outputs found

    HumanBench: Towards General Human-centric Perception with Projector Assisted Pretraining

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    Human-centric perceptions include a variety of vision tasks, which have widespread industrial applications, including surveillance, autonomous driving, and the metaverse. It is desirable to have a general pretrain model for versatile human-centric downstream tasks. This paper forges ahead along this path from the aspects of both benchmark and pretraining methods. Specifically, we propose a \textbf{HumanBench} based on existing datasets to comprehensively evaluate on the common ground the generalization abilities of different pretraining methods on 19 datasets from 6 diverse downstream tasks, including person ReID, pose estimation, human parsing, pedestrian attribute recognition, pedestrian detection, and crowd counting. To learn both coarse-grained and fine-grained knowledge in human bodies, we further propose a \textbf{P}rojector \textbf{A}ssis\textbf{T}ed \textbf{H}ierarchical pretraining method (\textbf{PATH}) to learn diverse knowledge at different granularity levels. Comprehensive evaluations on HumanBench show that our PATH achieves new state-of-the-art results on 17 downstream datasets and on-par results on the other 2 datasets. The code will be publicly at \href{https://github.com/OpenGVLab/HumanBench}{https://github.com/OpenGVLab/HumanBench}.Comment: Accepted to CVPR202

    Plasma Exosomal Long Non-Coding RNAs Serve as Biomarkers for Early Detection of Colorectal Cancer

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    Background/Aims: Colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the second leading cause of cancer-related deaths worldwide. Thus, methods for early diagnosis of CRC are urgently needed. We aimed to identify potential long non-coding RNAs (lncRNAs) in circulatory exosomes that may serve as biomarkers for the detection of early-stage CRC. Methods: Exosomes from the plasma of CRC patients (n = 50) and healthy individuals (n = 50) were isolated by ultracentrifugation, followed by extraction of total exosomal RNAs using TRIzol reagent. Microarray analysis was used for exosomal lncRNA profiling in the two groups, and real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was used to determine the expression level of lncRNAs in all patients and healthy subjects. Results: The expression of six lncRNAs (LNCV6_116109, LNCV6_98390, LNCV6_38772, LNCV_108266, LNCV6_84003, and LNCV6_98602) was found to be significantly up-regulated in CRC patients compared with that in healthy individuals by qRT-PCR. The receiver operating characteristic curve was used to verify their diagnostic accuracy. The values of the area under the curve for these lncRNAs were 0.770 (LNCV6_116109), 0.7500 (LNCV6_98390), 0.6500 (LNCV6_38772), 0.6900 (LNCV_108266), 0.7500 (LNCV6_84003), and 0.7200 (LNCV6_98602). Conclusion: Our study suggested that the expression of these six exosomal lncRNAs (LNCV6_116109, LNCV6_98390, LNCV6_38772, LNCV_108266, LNCV6_84003, and LNCV6_98602) was significantly up-regulated in the plasma of CRC patients, and that they may serve as potential non-invasive biomarkers for early diagnosis of CRC

    A novel causal structure-based framework for comparing a basin-wide water–energy–food–ecology nexus applied to the data-limited Amu Darya and Syr Darya river basins

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    The previous comparative studies on watersheds were mostly based on the comparison of dispersive characteristics, which lacked systemicity and causality. We proposed a causal structure-based framework for basin comparison based on the Bayesian network (BN) and focus on the basin-scale water–energy–food–ecology (WEFE) nexus. We applied it to the Syr Darya River basin (SDB) and the Amu Darya River basin (ADB), of which poor water management caused the Aral Sea disaster. The causality of the nexus was effectively compared and universality of this framework was discussed. In terms of changes in the nexus, the sensitive factor for the water supplied to the Aral Sea changed from the agricultural development during the Soviet Union period to the disputes in the WEFE nexus after the disintegration. The water–energy contradiction of the SDB is more severe than that of the ADB, partly due to the higher upstream reservoir interception capacity. It further made management of the winter surplus water downstream of the SDB more controversial. Due to this, the water–food–ecology conflict between downstream countries may escalate and turn into a long-term chronic problem. Reducing water inflow to depressions and improving the planting structure prove beneficial to the Aral Sea ecology, and this effect of the SDB is more significant. The construction of reservoirs on the Panj River of the upstream ADB should be cautious to avoid an intense water–energy conflict such as the SDB's. It is also necessary to promote the water-saving drip irrigation and to strengthen the cooperation

    Ultra-small topological spin textures with size of 1.3nm at above room temperature in Fe78Si9B13 amorphous alloy

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    Topologically protected spin textures, such as skyrmions1,2 and vortices3,4, are robust against perturbations, serving as the building blocks for a range of topological devices5-9. In order to implement these topological devices, it is necessary to find ultra-small topological spin textures at room temperature, because small size implies the higher topological charge density, stronger signal of topological transport10,11 and the higher memory density or integration for topological quantum devices5-9. However, finding ultra-small topological spin textures at high temperatures is still a great challenge up to now. Here we find ultra-small topological spin textures in Fe78Si9B13 amorphous alloy. We measured a large topological Hall effect (THE) up to above room temperature, indicating the existence of highly densed and ultra-small topological spin textures in the samples. Further measurements by small-angle neutron scattering (SANS) reveal that the average size of ultra-small magnetic texture is around 1.3nm. Our Monte Carlo simulations show that such ultra-small spin texture is topologically equivalent to skyrmions, which originate from competing frustration and Dzyaloshinskii-Moriya interaction12,13 coming from amorphous structure14-17. Taking a single topological spin texture as one bit and ignoring the distance between them, we evaluated the ideal memory density of Fe78Si9B13, which reaches up to 4.44*104 gigabits (43.4 TB) per in2 and is 2 times of the value of GdRu2Si218 at 5K. More important, such high memory density can be obtained at above room temperature, which is 4 orders of magnitude larger than the value of other materials at the same temperature. These findings provide a unique candidate for magnetic memory devices with ultra-high density.Comment: 26 pages, 4 figure

    We may be different, but I can help you: the effects of leaders’ political skills on leader–follower power distance value incongruence and withdrawal behavior

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    Based on a resource perspective, the authors investigated how leader–follower power distance value incongruence influences employees’ withdrawal behavior. Data were collected twice in China, and the sample included 66 leaders and 350 followers. Leader–follower power distance value incongruence was found to be associated with the psychological workplace strain experienced by followers, indicating that incongruence was a stressor for this group and further influenced their withdrawal behavior. Moreover, incongruence had asymmetrical effects; that is, followers experienced higher psychological workplace strain when their power distance was lower than that of their leaders, compared with when their power distance was higher. The authors also found that the leader’s role can make a difference, as the leaders’ political skill mitigated the effect of value incongruence on their followers’ psychological workplace strain. The study provides a novel extension of value congruence theory and also contributes to the field of value conflict management

    Evolution Rules of Fractures for Mudstone under Compression Shear Load and the Fractal Characteristics of Broken Blocks

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    Failure of rocks is commonly induced by compressive and shear coupling loading. Knowledge of the mechanism and process of deformation and failure of rocks under compressive shear loading condition is an important basis for the study of stability in rock engineering. Based on the nonlinear fractal theory, it is possible to examine the evolution rules of fractures in mudstone under compression shear load and the fractal characteristics of broken blocks using the shear compression test with variable angles of mudstone specimens in natural conditions. This research shows that the cohesion and friction angle parameters of rock samples are achieved by draw Mohr’s strength envelope according to the test date of variable-angle shear compression test. It also shows that the shape of load-displacement curves of rocks can be divided into four stages: compaction, elastic, plastic, and fracture, and the curve can accurately represent the transformation and breakage characteristics of rock during shear fracture. And the distribution of broken blocks shows a strong statistical resemblance to the fractal distribution, and the fractal dimension is able to reflect the distribution characteristics of broken blocks. With increasing the shear angle, the fractal dimension of broken blocks decreases in a logarithmic relationship

    Valence of Precursor Compound Effects on the Stability and Composition of Cu/Cl Binary Cluster Produced by Laser Vaporization

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    The production mechanism of Cu/Cl binary clusters were investigated by laser vaporization of CuCl1 CuCl2, CuCl2 center dot 2H(2)O by time-of-flight mass spectrometry. We found that lager cluster size can be detected by using CuCl2 center dot 2H(2)O solid pellets than CuCl2 and CuCl. Only Cu+(CuCl)(n), (CuCl)(n)(+), n<8 were observed when 532 nm laser vaporized the Cucl. We also found almost the same cluster using CuCl2 and CuCl2 center dot 2H(2)O in the same mass range, deficit Cu clusters were dominated for clusters with more than five Cu atoms when using CuCl2, CuCl2 center dot 2H(2)O compounds. the relation of relative intensity I-n(2)/In-1In+2 vs, different size of clusters were almost the same using different compounds above. (CuCl)(3)(+)center dot(CuCl)(6)(+) ions in (CuCi)(n)(+) series, and Cu6Cl5+ in Cu(CuCl)(n)(+) series have special stability. The magic number observed above are different from those of alkali halide (MX) clusters, hexagonal structures were proposed for the above magic number clusters
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