Effect of Morinda citrifolia juice on the bonding strength and nanoleakage of crowns dentin

Objective To explore the effect of Morinda citrifolia juice (MCJ) combined with ethylene diamine tetraacetic acid (EDTA) on premolar bonding strength and nanoleakage and compare the results with those of the most commonly used root canal irrigation solution, sodium hypochlorite (NaClO), to provide a reference for clinical application. Methods This study was approved by the ethics review committee. Sixty-three human premolars extracted for orthodontic treatment were randomly divided into a control group (distilled water group) and 6 experimental groups according to the different rinsing solutions used after the surface enamel was removed. The experimental groups included Group A (2.5% NaClO), Group B (5.25% NaClO), Group C (6% MCJ), Group D (2.5% NaClO-17% EDTA), Group E (5.25% NaClO-17% EDTA), and Group F (6% MCJ-17% EDTA) (n = 9). After soaking in the corresponding rinsing solution for 20 minutes, they were layered and stacked on their surfaces to form 4 mm × 4 mm × 3 mm Z350 resin blocks. Six samples from each group were cut into 1 mm × 1 mm × 8 mm specimen strips for microtensile bonding strength testing. The fracture type was determined under a stereomicroscope, and the remaining 3 samples from each group were aged and cut into 1 mm thick slices for interface nanoleakage testing and scanning electron microscopy observation of the resin dentin bonding interface. Results There were significant differences in the microtensile bonding strength among the groups (P<0.05), and the control group had the highest bonding strength. Among experimental groups, Group B had the lowest bonding strength, mainly bonding interface fracture, and Group F had the highest bonding strength, mainly mixed fracture. There were significant differences in nanoleakage among all groups (P<0.05), and the control group had the lowest nanoleakage value. Among experimental groups, Group B had the highest nanoleakage, with resin protrusions being unaltered, and Group F had the lowest nanoleakage value, with resin protrusions being thick and dense. Conclusion The higher the concentration of NaClO was, the worse the bonding strength and edge sealing of the crown dentin were. The effects of root canal irrigation with MCJ and EDTA on the adhesive strength and edge sealing of crown dentin were less pronounced than those of root canal irrigation with NaClO and EDTA

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

3D Numerical Analysis of Synergetic Interaction between High-Rise Building Basement and CFG Piles Foundation

A strong bearing capacity and the satisfaction of strict settlement requirements are necessary for high-rise buildings. A single-raft foundation cannot meet certain settlement requirements, in which case CFG (cement/fly ash/gravel, an emerging and sustainable construction material) piles can be used in the foundation to set up a cushion between the top of the pile and the raft slab, where the piles act as settlement reducers. The rafts of disconnected piles (DPs) exhibit complex synergetic interactions involving the raft, cushion, pile, and soil under the load of the superstructure. Multiple piles in particular lead to an increase in the number of degrees of freedom of the problem, resulting in difficulty in solving it. However, when the number of piles is very large and the structure is complex—for example, many buildings are placed on the same raft with basement structures—even if the embedded pile element is used during numerical calculations, either the method remains prone to non-convergence or the time needed for numerical calculations is too long. It is, thus, difficult to satisfy the requirement of an efficient scheme of evaluation in practice. To solve this problem, a method that uses a simulation of the integral equivalent of the CFG pile reinforcement zone is proposed in this paper. In the CFG pile reinforcement zone, the effect of the pile is reflected in the enhancement of parameters of the soil in the strengthened zone, and the reinforcement zone (including the soil and the pile) is regarded as an anisotropic elastoplastic material. As the structure of the pile is no longer needed in the model, its elimination significantly reduces the complexity of the model and improves its calculation efficiency. An example of a numerical calculation is provided to verify the viability and accuracy of the integral equivalent simulation method in comparison with the embedded pile element simulation method. Finally, the proposed method is applied to the three-dimensional numerical analysis of a scheme for the treatment of foundations of high- and low-rise buildings with basements, and its effectiveness is further verified through comparison with theoretical results

Designing highly efficient oxygen evolution reaction electrocatalyst of high-entropy oxides FeCoNiZrOx: Theory and experiment

Summary: The correlations between the experimental methods and catalytic activities are urgent to be defined for the design of highly efficient catalysts. In this work, a new oxygen evolution reaction electrocatalyst of high-entropy oxide (HEO) FeCoNiZrOx was designed and analyzed by experimental and theoretical methods. On account of the shortened coordinate bond along with the increased annealing temperature, the atomic/electronic structures of active site were adjusted quantitatively with the aid of the pre-designed correlator of d electron density, which contributed to adjust the catalytic activity of HEO specimens. The prepared HEO specimen exhibited the low overpotentials of 245 mV at 10 mA cm−2 and 288 mV at 100 mA cm−2 with small Tafel slope of 35.66 mV dec−1, fast charge transfer rate, and stable electrocatalytic activity. This strategy would be adopted to improve the catalytic activity of HEO by adjusting the d electron density of transition metal ions with suitable preparation method

A Comprehensive and Automated Fusion Method: The Enhanced Flexible Spatiotemporal DAta Fusion Model for Monitoring Dynamic Changes of Land Surface

Spatiotemporal fusion methods provide an effective way to generate both high temporal and high spatial resolution data for monitoring dynamic changes of land surface. But existing fusion methods face two main challenges of monitoring the abrupt change events and accurately preserving the spatial details of objects. The Flexible Spatiotemporal DAta Fusion method (FSDAF) was proposed, which can monitor the abrupt change events, but its predicted images lacked intra-class variability and spatial details. To overcome the above limitations, this study proposed a comprehensive and automated fusion method, the Enhanced FSDAF (EFSDAF) method and tested it for Landsat–MODIS image fusion. Compared with FSDAF, the EFSDAF has the following strengths: (1) it considers the mixed pixels phenomenon of a Landsat image, and the predicted images by EFSDAF have more intra-class variability and spatial details; (2) it adjusts the differences between Landsat images and MODIS images; and (3) it improves the fusion accuracy in the abrupt change area by introducing a new residual index (RI). Vegetation phenology and flood events were selected to evaluate the performance of EFSDAF. Its performance was compared with the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM), the Spatial and Temporal Reflectance Unmixing Model (STRUM), and FSDAF. Results show that EFSDAF can monitor the changes of vegetation (gradual change) and flood (abrupt change), and the fusion images by EFSDAF are the best from both visual and quantitative evaluations. More importantly, EFSDAF can accurately generate the spatial details of the object and has strong robustness. Due to the above advantages of EFSDAF, it has great potential to monitor long-term dynamic changes of land surface

Age attribution of coal bearing strata in Beishan Basin Group, Ganmeng area

A large number of coal bearing strata are developed in Beishan Basin Group of Ganmeng area.However, due to the complexity of tectonic evolution, lack of seismic, drilling and related paleontological data, the age of coal bearing strata has been controversial, and the potential of resources is not clear.On the basis of summarizing the previous research results, taking paleontology chronology as the starting point, combining the characteristics of rock assemblage, coal industrial characteristics, seismic data, outcrop data and other evidence, the age attribution of coal bearing strata in Beishan Basin Group is studied.According to the analysis of sporopollen paleontology, coal petrology industrial characteristics and stratigraphic contact relationship, it is considered that each basin of Beishan Basin Group has developed a set of coal bearing series, but the age of this coal bearing system is not the same.Some are Jurassic and some are Cretaceous, but the possibility of Triassic or Permian is ruled out.Only the coal bearing strata in the southern part of Zhongkouzi Basin in the southernmost part of Beishan Basin Group and the eastern part of Heiyingshan Basin in the northernmost part of the basins group are Jurassic, and the coal bearing rock series of other sub basins belong to Cretaceous.The coal bearing strata in Zhongkouzi Basin in the southern part of the basins group show a "North-South difference" consistent with the structure features.The age of the exposed coal bearing strata in the south is Middle Jurassic, and that in the north is Cretaceous.The classification of the coal bearing series provides a basis for further determining the resource potential of Beishan Basin Group, and provides a reference for the study of the prototype basin restoration and tectonic evolution of the coal bearing series in the Beishan Basin Group

SQNet: Simple and Fast Model for Ocean Front Identification

The ocean front has a non-negligible role in global ocean–atmosphere interactions, marine fishery production, and the marine military. Hence, obtaining the positions of the ocean front is crucial in oceanic research. At present, the positioning method of recognizing an ocean front has achieved a breakthrough in the mean dice similarity coefficient (mDSC) of above 90%, but it is difficult to use to achieve rapid extraction in emergency scenarios, including marine fisheries and search and rescue. To reduce the its dependence on machines and apply it to more requirements, according to the characteristics of an ocean front, a multi-scale model SQNet (Simple and Quick Net) dedicated to ocean front position recognition is designed, and its perception domain is expanded while obtaining current scale data. In experiments along the coast of China and the waters of the Gulf of Mexico, it was not difficult to find that SQNet exceedingly reduced running time while ensuring high-precision results (mDSC of higher than 90%). Then, after conducting intra-model self-comparison, it was determined that expanding the perceptual domain and changing the weight ratio of the loss function could improve the accuracy and operational efficiency of the model, which could be better applied in ocean front recognition