Plasmon-Modulated Photoluminescence of Individual Gold Nanostructures

In this work, we performed a systematic study on the photoluminescence and scattering spectra of individual gold nanostructures that were lithographically defined. We identify the role of plasmons in photoluminescence as modulating the energy transfer between excited electrons and emitted photons. By comparing photoluminescence spectra with scattering spectra, we observed that the photoluminescence of individual gold nanostructures showed the same dependencies on shape, size, and plasmon coupling as the particle plasmon resonances. Our results provide conclusive evidence that the photoluminescence in gold nanostructures indeed occurs <i>via</i> radiative damping of plasmon resonances driven by excited electrons in the metal itself. Moreover, we provide new insight on the underlying mechanism based on our analysis of a reproducible blue shift of the photoluminescence peak (relative to the scattering peak) and observation of an incomplete depolarization of the photoluminescence

The relationship between the average optical density (AOD) scores of MACC1 immunohistochemical (IHC) staining obtained in Image Pro Plus anaysis and the staining intensity scores determined by visual assessment.

<p>(A), Patients with RPC were manually divided into three groups according to their visual assessment scores in IHC stained tissue sections (negative, low MACC1 expression group, and high MACC1 expression group, respectively). The AOD value of MACC1 obtained from Image Pro Plus analysis was evidently increased in the low MACC1 expression group compared to the negative group, and was further elevated in the high MACC1 expression group (<i>p</i><0.001). AOD =  the integrated optical density (IOD)/Area of positive MACC1 staining in each IHC staining image; B, Spearman correlation coefficient analysis measuring the strength of the linear relationship between MACC1 AOD Image Pro Plus scores and visual assessment scores. A statistically significant positive linear relationship was observed between these two sets of scores in RPC (<i>r</i> = 0.669, <i>p</i><0.001).</p

Univariate Cox regression analysis of several prognostic factors (age, gender, TNM stage, nuclear grade, and MACC1 protein expression levels) with respect to five-year overall survival (OS) and disease-free survival (DFS) of patients with renal pelvis carcinoma.

<p>‘CI’ refers to confidence interval; ‘HR’ refers to hazard ratio.</p

Boosting the Efficiency of High-Resolution Quantum Dot Light-Emitting Devices Based on Localized Surface Plasmon Resonance

With pixel miniaturization, the performance of high-resolution quantum dot light-emitting diodes (QLEDs) usually degrades. Considering the dimension of ultrasmall pixels, herein, a barrier architecture based on localized surface plasmon resonance (LSPR) that promotes the radiative recombination of neighboring quantum dots is rationally designed to improve the device performance. Au nanoparticles (NPs) are embedded in an insulating polymer to form a honeycomb-patterned barrier layer via the nanoimprint process. Each pixel fabricated in the void area (average diameter of 1.5 μm) of the barrier layer is surrounded by a number of LSPR-NPs to enhance the luminescence. The resultant green QLEDs with a resolution of 9027 pixels per inch show a maximum external quantum efficiency of 11.1%, a 42.8% enhancement compared to the control device. Additionally, the lifetime of high-resolution QLEDs is obviously improved by the LSPR effect

Representative illustrations of immunohistochemical (IHC) staining of MACC1 in the normal renal pelvis (A & A′, B & B′) and in renal pelvis carcinoma (RPC) tissue samples (C–E & C′–E′).

<p>(A) negtive control staining; (B) MACC1 positive staining; (C–E) representative images of negtive, low, high MACC1 expression in RPC tissues, respectively. (A′–E′) a higher magnification of the selected area in (A–E), respectively. Magnification: ×100 in (A–E); ×200 in (A′–E′).</p

The correlation between immunohistochemical scores of MACC1 protein expression (indicated as the values of the average optical density (AOD) measured by Image Pro Plus in renal pelvis carcinoma tissue sections) and prognostic factors (gender, age, TNM stage, and nuclear grade).

<p>The correlation between immunohistochemical scores of MACC1 protein expression (indicated as the values of the average optical density (AOD) measured by Image Pro Plus in renal pelvis carcinoma tissue sections) and prognostic factors (gender, age, TNM stage, and nuclear grade).</p

The average optical density (AOD) of immunohistochemical (IHC) staining strength of MACC1 was measured quantitatively by Image Pro Plus in renal pelvis carcinoma (RPC) tissue specimens, adjacent non-tumorous renal pelvis epithelial tissue (ANRPET) and normal renal pelvis epithelial tissue (NRPET) specimens.

<p>Since there was no substantial difference between ANRPETs and NRPETs (<i>p</i>>0.05), these two groups were combined as a single group, ‘normal epithelium (NE)’.</p><p>*ANRPETs VS NRPETs.</p>#<p>RPC VS NE.</p

Kaplan–Meier survival analysis.

<p>The Kaplan–Meier survival curves revealed that patients in the high MACC1 expression group demonstrated significantly shorter overall survival (OS) (<i>p</i><0.001) (A) and disease-free survival (DFS) (<i>p</i><0.001) (B) rates than those in the low MACC1 expression group.</p

Multivariate Cox regression analysis of several prognostic factors (TNM stage, nuclear grade, and MACC1 protein expression levels) with respect to five-year overall survival (OS) and disease-free survival (DFS) of patients with renal pelvis carcinoma (RPC).

<p>‘CI’ refers to confidence interval; ‘HR’ refers to hazard ratio.</p

Video1_To use a simple hernia needle for single-port laparoscopic percutaneous inguinal hernia repair in children: a 5-year experience study.mp4

PurposeThe aim of this study is to investigate the technique and practical significance of using a simple hernia needle in single-port laparoscopic herniorrhaphy in pediatric patients.MethodsThe study conducted a retrospective analysis of all pediatric patients who underwent treatment for inguinal hernia using single-port laparoscopic herniorrhaphy with a simple hernia needle at Yellow River Sanmenxia Hospital from June 2018 to May 2023. The medical records of all the children were collected, and clinical characteristics, procedural information, and follow-up data were carefully reviewed.ResultsA total of 848 patients underwent inguinal hernia repair, with ages ranging from 7 months to 13 years (2.99 ± 2.49 years), including 756 males and 92 females. A total of 528 cases of unilateral hernia and 310 cases of bilateral hernia were reported, with intra-operative findings revealing contralateral occult hernia in 253 cases. Single-port laparoscopic herniorrhaphy was successfully completed in all patients, with no instances of conversion to open surgery. The mean operation time for unilateral hernia repair was (7.50 ± 4.80) min, while for bilateral hernia repair it was (11.55 ± 7.27) min. Five patients presented with subcutaneous emphysema, while two patients experienced a recurrence of inguinal hernia. No complications, such as scrotal hematoma, trocar umbilical hernia and testicular atrophy, were observed. The duration of the follow-up period ranged from 3 to 24 months.ConclusionThe promotion and utilization of single-port laparoscopy combined with a simple hernia needle in clinical practice are justified. Our initial investigation indicates that this surgical approach is both safe and dependable for the management of pediatric inguinal hernia. The procedure presents numerous benefits, including the utilization of uncomplicated instruments, straightforward operation, a clear curative impact, minimal tissue damage, rapid recovery, and the absence of scarring.</p