Three polymorphs (alpha, beta, and delta) of D-mannitol at 100 K

In the monoclinic delta polymorph of D-mannitol, C(6)H(14)O(6), both the molecule and the packing have approximate twofold rotational symmetry. The P2(1) structure thus approximates space group C222(1), and the alpha\u27 polymorph, previously reported in that space group, is almost certainly identical to the delta polymorph. However, torsion angles along the main backbone of the molecule deviate from twofold symmetry by as much as 7.4 (3) degrees and the hydrogen-bonding pattern does not conform to the higher symmetry. The alpha polymorph reported here is identical to the previously reported kappa polymorph, and the low-temperature structure of the beta polymorph agrees well with previously reported room-temperature determinations. The range of C-O bond lengths over the three polymorphs is 1.428 (2)-1.437 (4) A, and the range of C-C distances is 1.515 (4)-1.5406 (19) A. The delta polymorph has the highest density of the three, both at room temperature and at 100 K

Effect of iron deficiency on behavior and cognition in children

Background: Iron deficiency (ID) is the most common trace element deficiency in childhood. More than 25% of the world’s population is affected by anemia, of which more than 50% suffers from iron deficiency anemia (IDA). Iron deficiency can cause changes in neurotransmitter homeostasis, decrease myelin production, impair synaptogenesis, and decline the function of the basal ganglia. Therefore, IDA adversely affects cognitive functions and psychomotor development. Aim: is to study the effect of iron deficiency on behavior and cognitive function in children using conners parent rating scales and P300 event-related potentials (ERPs). Patients and Methods: This is a cross sectional comparative study included 20 children with iron deficiency, 20 children ​with iron deficiency anemia,and 20 healthy children who attended the pediatric out patient’s clinic and inpatient department of Al-Zahraa hospital –Alazhar University for Girls we include children with iron deficiency ,Children with chronic medical conditions,Children with co-morbid psychiatric diagnoses ,children with any form of psychiatric, physical, developmental or Intellectual  disability, chronic underlying disease (e.g. inborn error of metabolism, genetic, endocrine or liver disease, vision or hearing impairment) or neurologic disorders were excluded from the study.&nbsp