860 research outputs found

    Constraint of ξ\xi-moments calculated with QCD sum rules on the pion distribution amplitude models

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    So far, the behavior of the pionic leading-twist distribution amplitude (DA) ϕ2;π(x,μ)\phi_{2;\pi}(x,\mu) −- which is universal physical quantity and enters the high-energy processes involving pion based on the factorization theorem −- has not been completely consistent. The form of ϕ2;π(x,μ)\phi_{2;\pi}(x,\mu) is usually described by phenomenological models and constrained by the experimental data of the exclusive processes containing pion or the moments calculated with the QCD sum rules and lattice QCD theory. Obviously, an appropriate model is very important for us to determine the exact behavior of ϕ2;π(x,μ)\phi_{2;\pi}(x,\mu). In this paper, by adopting the least squares method to fit the ξ\xi-moments calculated with QCD sum rules based on the background field theory, we perform an analysis for several commonly used models of the pionic leading-twist DA in the literature, such as the truncation form of the Gegenbauer polynomial series, the light-cone harmonic oscillator model, the form from the Dyson-Schwinger equations, the model from the light-front holographic AdS/QCD and a simple power-law parametrization form.Comment: 10 pages, 2 figure

    Top quark pair production at small transverse momentum in hadronic collisions

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    We investigate the transverse momentum resummation for top quark pair production at hadron colliders using the soft-collinear effective theory and the heavy-quark effective theory. We derive the factorization formula for ttˉt\bar{t} production at small pair transverse momentum, and show in detail the procedure for calculating the key ingredient of the factorization formula: the next-to-leading order soft functions. We compare our numerical results with experimental data and find that they are consistent within theoretical and experimental uncertainties. To verify the correctness of our resummation formula, we expand it to the next-to-leading order and the next-to-next-to-leading order, and compare those expressions with the exact fixed-order results numerically. Finally, using the results of transverse momentum resummation, we discuss the transverse-momentum-dependent forward-backward asymmetry at the Tevatron.Comment: 39 pages, 7 figures, 1 table; final version in PR

    A disulfidptosis-related lncRNA prognostic model to predict survival and response to immunotherapy in lung adenocarcinoma

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    Background: Lung adenocarcinoma (LUAD) is the major subtype of lung cancer and has a poor prognosis. Disulfidptosis is a novel regulated cell death form characterized by aberrant disulfide stress and actin network collapse. This study aimed to identify disulfidptosis-related lncRNAs, and predict LUAD patients’ prognosis and response to antitumor therapies by establishing a disulfidptosis-related lncRNA model.Methods: Transcriptome and clinical data of LUAD patients were obtained from the TCGA database. Pearson correlation and Cox regression analysis was used to identify disulfidptosis-related lncRNAs associated with overall survival. LASSO regression analysis was adopted to construct the prognostic model. GO, KEGG and GSEA analysis was used to identify cellular pathways related to this model. Immune cell infiltration was investigated by ESTIMATE and CIBERSORT algorithms. Tumor mutational burden (TMB) and its association with model-derived risk score were analyzed using simple nucleotide variation data. Patients’ response to immunotherapy and other antineoplastic drugs was predicted by the TIDE algorithm and GDSC tool, respectively.Results: We identified 127 disulfidptosis-related lncRNAs, and a prognostic model that consists eight of them (KTN1-AS1, AL365181.3, MANCR, LINC01352, AC090559.1, AC093673.1, AP001094.3, and MHENCR) was established and verified. The prognostic model could stratify LUAD patients into two distinct risk-score groups. A high risk score was an independent prognosis factor indicating poor overall survival, and correlated with reduced immune cell infiltration, high TMB, and lower activity of tumor immune response. Immune checkpoint blockade might bring more survival benefits to the high-risk LUAD patients, whereas low-risk patients might be more responsive to targeted therapy and diverse kinase inhibitors.Conclusion: We established a disulfidptosis-related lncRNA model that can be exploited to predict the prognosis, tumor mutational burden, immune cell infiltration landscape, and response to immunotherapy and targeted therapy in LUAD patients

    New fossil seeds of Eurya (Theaceae) from East Asia and their paleobiogeographic implications

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    AbstractEurya has an excellent fossil record in Europe, but it has only a few fossil occurrences in East Asia though this vast area houses the highest modern diversity of the genus. In this study, three-dimensionally preserved fossil seeds of Eurya stigmosa (Ludwig) Mai from the late Pliocene of northwestern Yunnan, southwestern China are described. The seeds are compressed and flattened, slightly campylotropous, and nearly circular to slightly angular in shape. The surface of the seeds is sculptured by a distinctive foveolate pattern, consisting of funnel-shaped and finely pitted cells. Each seed valve contains a reniform or horseshoe-shaped embryo cavity, a characteristic condyle structure and an internal raphe. These fossil seeds represent one of the few fossil records of Eurya in East Asia. This new finding therefore largely extends the distributional ranges of Eurya during Neogene. Fossil records summarized here show that Eurya persisted in Europe until the early Pleistocene, but disappeared thereafter. The genus might have first appeared in East Asia no later than the late Oligocene, and dispersed widely in regions such as Japan, Nepal, and southwestern China
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