The puzzle of anomalously large isospin violations in η(1405/1475)→3π\eta(1405/1475)\to 3\pi

The BES-III Collaboration recently report the observation of anomalously large isospin violations in $J/\psi\to \gamma\eta(1405/1475) \to \gamma \pi^0 f_0(980)\to \gamma +3\pi$, where the $f_0(980)$ in the $\pi\pi$ invariant mass spectrum appears to be much narrower ($\sim$ 10 MeV) than the peak width ($\sim$50 MeV) measured in other processes. We show that a mechanism, named as triangle singularity (TS), can produce a narrow enhancement between the charged and neutral $K\bar{K}$ thresholds, i.e., $2m_{K^\pm}\sim 2m_{K^0}$. It can also lead to different invariant mass spectra for $\eta(1405/1475)\to a_0(980)\pi$ and $K\bar{K}^*+c.c.$, which can possibly explain the long-standing puzzle about the need for two close states $\eta(1405)$ and $\eta(1475)$ in $\eta\pi\pi$ and $K\bar{K}\pi$, respectively. The TS could be a key to our understanding of the nature of $\eta(1405/1475)$ and advance our knowledge about the mixing between $a_0(980)$ and $f_0(980)$.Comment: 4 pages and 7 eps figures; Journal-matched versio

Revised Constraints on the fast radio burst population from the first CHIME/FRB catalog

In this paper, we investigate the FRB population using the first CHIME/FRB catalog. We first reconstruct the extragalactic dispersion measure -- redshift relation ($\mathrm{DM_E} - z$ relation) from well-localized FRBs, then use it to infer redshift and isotropic energy of the first CHIME/FRB catalog. The intrinsic energy distribution is modeled by the power law with an exponential cutoff, and the selection effect of the CHIME telescope is modeled by a two-parametric function of specific fluence. For the intrinsic redshift distribution, the star formation history (SFH) model, as well as other five SFH-related models are considered. We construct the joint likelihood of fluence, energy and redshift, and all the free parameters are constrained simultaneously using Bayesian inference method. The Bayesian information criterion (BIC) is used to choose the model that best matches the observational data. For comparison, we fit our models with two data samples, i.e. the Full sample and the Gold sample. The power-law index and cutoff energy are tightly constrained to be $1.8 \lesssim \alpha \lesssim 2.0$ and $\mathrm{log}(E_c/{\rm erg}) \approx 42.5$, which are almost independent of the redshift distribution model and the data sample we choose. The parameters involving the selection effect strongly depends on the data sample, but are insensitive to the redshift distribution model. According to BIC, the pure SFH model is strongly disfavored by both the Full sample and Gold sample. For the rest five SFH-related redshift distribution models, most of them can match the data well if the parameters are properly chosen. Therefore, with the present data, it is still premature to draw a conclusive conclusion on the FRB population.Comment: 13 pages, 16 figure

PEDF in Diabetic Retinopathy: A Protective Effect of Oxidative Stress

Diabetic retinopathy (DR) is a major cause of blindness in working age adults, and oxidative stress plays a vital role in the pathogenesis of DR. Pigment-epithelium-derived factor (PEDF), a multifunctional protein, has shown to inhibit the development of DR by accumulating evidence. This paper highlights the current understanding of probable mechanism about how PEDF blocks the deterioration of DR through its antioxidative properties and application prospects of PEDF as a novel therapeutic target in DR. Gene therapy of PEDF is becoming more and more acceptable and will widely be applied to the actual treatment in the near future

Effects of Helicobacter pylori

Infection of Helicobacter pylori (H. pylori) changed the proliferation of gastric epithelial cells and decreased the expression of heat shock protein 70 (HSP70). However, the effects of H. pylori on the proliferation of gastric epithelial cells and the roles of HSP70 during the progress need further investigation. Objective. To investigate the effects of Helicobacter pylori (H. pylori) and heat shock protein 70 (HSP70) on the proliferation of human gastric epithelial cells. Methods. H. pylori and a human gastric epithelial cell line (AGS) were cocultured. The proliferation of AGS cells was quantitated by an MTT assay, and the expression of HSP70 in AGS cells was detected by Western blotting. HSP70 expression in AGS cells was silenced by small interfering RNA (siRNA) to investigate the role of HSP70. The siRNA-treated AGS cells were cocultured with H. pylori and cell proliferation was measured by an MTT assay. Results. The proliferation of AGS cells was accelerated by coculturing with H. pylori for 4 and 8 h, but was suppressed at 24 and 48 h. HSP70 expression was decreased in AGS cells infected by H. pylori for 48 h. The proliferation in HSP70-silenced AGS cells was inhibited after coculturing with H. pylori for 24 and 48 h compared with the control group. Conclusions. Coculture of H. pylori altered the proliferation of gastric epithelial cells and decreased HSP70 expression. HSP70 knockdown supplemented the inhibitory effect of H. pylori on proliferation of epithelial cells. These results indicate that the effects of H. pylori on the proliferation of gastric epithelial cells at least partially depend on the decreased expression of HSP70 induced by the bacterium

Orbital density wave induced by electron-lattice coupling in orthorhombic iron pnictides

In this paper we explore the magnetic and orbital properties closely related to a tetragonal-orthorhombic structural phase transition in iron pnictides based on both two- and five-orbital Hubbard models. The electron-lattice coupling, which interplays with electronic interaction, is self-consistently treated. Our results reveal that the orbital polarization stabilizes the spin density wave (SDW) order in both tetragonal and orthorhombic phases. However, the ferro-orbital density wave (F-ODW) only occurs in the orthorhombic phase rather than in the tetragonal one. Magnetic moments of Fe are small in the intermediate Coulomb interaction region for the striped antiferromangnetic phase in the realistic five orbital model. The anisotropic Fermi surface in the SDW/ODW orthorhombic phase is well in agreement with the recent angle-resolved photoemission spectroscopy experiments. These results suggest a scenario that the magnetic phase transition is driven by the ODW order mainly arising from the electron-lattice coupling.Comment: 21 pages, 10 figure

Revised constraints on the photon mass from well-localized fast radio bursts

We constrain the photon mass from well-localized fast radio bursts (FRBs) using Bayes inference method. The probability distributions of dispersion measures (DM) of host galaxy and intergalactic medium are properly taken into account. The photon mass is tightly constrained from 17 well-localized FRBs in the redshift range $0<z<0.66$. Assuming that there is no redshift evolution of host DM, the $1\sigma$ and $2\sigma$ upper limits of photon mass are constrained to be $m_\gamma<4.8\times 10^{-51}$ kg and $m_\gamma<7.1\times 10^{-51}$ kg, respectively. Monte Carlo simulations show that, even enlarging the FRB sample to 200 and extending the redshift range to $0<z<3$ couldn't significantly improve the constraining ability on photon mass. This is because of the large uncertainty on the DM of intergalactic medium.Comment: 9 pages, 4 figure