779 research outputs found
Cinnamic aldehyde treatment alleviates chronic unexpected stress-induced depressive-like behaviors via targeting cyclooxygenase-2 in mid-aged rats
Ethnopharmacological relevance: COX-2 has been considered as a potent molecular target for prevention and therapy of depression. However, a recent study showed that COX-2 inhibitor does not improve depressive symptoms in persons aged 70 and over. Therefore, whether treatments targeting COX-2 have a clinical efficacy in depression, especially elderly individuals, remains unclear. Cinnamic aldehyde is a major constituent of Cinnamomum cassia, which has exhibited excellent anti-inflammatory activities as a COX-2 inhibitor. To investigate the potential antidepressant effect of cinnamic aldehyde in mid-aged rats
Searching for doubly charmed tetraquark candidates and in decays
In this work, we propose to search for the exotic doubly charmed meson
and its analog in decays, which provide a
good environment for the formation of the exotic state containing double charm
quarks. Within the molecular scheme, the production of and
through various rescattering processes with different
intermediate states are investigated. For the moderate values of model
parameters, the branching ratios of decaying into , , and
are estimated to be of the order of ,
, and , respectively, which may be tested by future
experiments.Comment: 9 pages, 8 figure
PanoGRF: Generalizable Spherical Radiance Fields for Wide-baseline Panoramas
Achieving an immersive experience enabling users to explore virtual
environments with six degrees of freedom (6DoF) is essential for various
applications such as virtual reality (VR). Wide-baseline panoramas are commonly
used in these applications to reduce network bandwidth and storage
requirements. However, synthesizing novel views from these panoramas remains a
key challenge. Although existing neural radiance field methods can produce
photorealistic views under narrow-baseline and dense image captures, they tend
to overfit the training views when dealing with \emph{wide-baseline} panoramas
due to the difficulty in learning accurate geometry from sparse
views. To address this problem, we propose PanoGRF, Generalizable Spherical
Radiance Fields for Wide-baseline Panoramas, which construct spherical radiance
fields incorporating scene priors. Unlike generalizable radiance
fields trained on perspective images, PanoGRF avoids the information loss from
panorama-to-perspective conversion and directly aggregates geometry and
appearance features of 3D sample points from each panoramic view based on
spherical projection. Moreover, as some regions of the panorama are only
visible from one view while invisible from others under wide baseline settings,
PanoGRF incorporates monocular depth priors into spherical depth
estimation to improve the geometry features. Experimental results on multiple
panoramic datasets demonstrate that PanoGRF significantly outperforms
state-of-the-art generalizable view synthesis methods for wide-baseline
panoramas (e.g., OmniSyn) and perspective images (e.g., IBRNet, NeuRay)
Multifaceted roles of transcription factors during plant embryogenesis
Transcription factors (TFs) are diverse groups of regulatory proteins. Through their specific binding domains, TFs bind to their target genes and regulate their expression, therefore TFs play important roles in various growth and developmental processes. Plant embryogenesis is a highly regulated and intricate process during which embryos arise from various sources and undergo development; it can be further divided into zygotic embryogenesis (ZE) and somatic embryogenesis (SE). TFs play a crucial role in the process of plant embryogenesis with a number of them acting as master regulators in both ZE and SE. In this review, we focus on the master TFs involved in embryogenesis such as BABY BOOM (BBM) from the APETALA2/Ethylene-Responsive Factor (AP2/ERF) family, WUSCHEL and WUSCHEL-related homeobox (WOX) from the homeobox family, LEAFY COTYLEDON 2 (LEC2) from the B3 family, AGAMOUS-Like 15 (AGL15) from the MADS family and LEAFY COTYLEDON 1 (LEC1) from the Nuclear Factor Y (NF-Y) family. We aim to present the recent progress pertaining to the diverse roles these master TFs play in both ZE and SE in Arabidopsis, as well as other plant species including crops. We also discuss future perspectives in this context
VMesh: Hybrid Volume-Mesh Representation for Efficient View Synthesis
With the emergence of neural radiance fields (NeRFs), view synthesis quality
has reached an unprecedented level. Compared to traditional mesh-based assets,
this volumetric representation is more powerful in expressing scene geometry
but inevitably suffers from high rendering costs and can hardly be involved in
further processes like editing, posing significant difficulties in combination
with the existing graphics pipeline. In this paper, we present a hybrid
volume-mesh representation, VMesh, which depicts an object with a textured mesh
along with an auxiliary sparse volume. VMesh retains the advantages of
mesh-based assets, such as efficient rendering, compact storage, and easy
editing, while also incorporating the ability to represent subtle geometric
structures provided by the volumetric counterpart. VMesh can be obtained from
multi-view images of an object and renders at 2K 60FPS on common consumer
devices with high fidelity, unleashing new opportunities for real-time
immersive applications.Comment: Project page: https://bennyguo.github.io/vmesh
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