A long-lasting, complete hematologic and cytogenetic remission of chronic myelogenous leukemia after treatment with busulfan alone

A 44-year-old man suffering from cytogenetically and molecularly proven Philadelphia translocation-positive chronic myelogenous leukemia in chronic phase was treated with busulfan for 18 months and studied during a follow-up period of 13 years. Hematologically and cytogenetically, he attained a continuing complete remission, although at one point (9.5 years) at least, after attaining complete remission molecular analysis indicated the presence of minimal residual disease

Drug use, impaired driving and traffic accidents.

This literature review provides a comprehensive report on the relationship between drug use, impaired driving and traffic accidents. It covers methodological issues, presents results of prevalence surveys among drivers and provides an overview of findings from major international epidemiological surveys published since 1999. The report also gathers evidence from experimental and field studies of the relationship between drug use, driving impairment and traffic accidents Table of contents • Methodological issues in determining the relationship between drug consumption, impaired driving and traffic accidents • Prevalence of drugs in drivers • Effects and risks associated with drugs • Overall conclusio