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Fault-tolerant hardware designs and their reliability analysis
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Fault-tolerance, which is a complement to fault prevention, is an effective method of achieving ultra-high reliability. By taking this approach fault free computation can be achieved despite the presence of fault in the system. In this thesis three new fault tolerant techniques are presented and their advantages over well known fault-tolerant strategies are shown. One of these new techniques achieves higher reliability than any other similar techniques presented in the literature. Generally fault-tolerant structures consist of four major blocks: the replicated modules, the disagreement and detection circuit, the switching circuit, and the voting mechanism. The most critical component in a fault-tolerant system is the voter because the final output of the system is computed by this component. This dissertation presents a new implementation for voters which reduces both the complexity and the occupied area on the chip. The structures of the three techniques developed in this work are such that the complexity of their switching mechanisms grows only linearly with the number of modules but the voting mechanism complexity increases significantly. This is a better approach than those schemes in which the switching complexity increases significantly and the voter's complexity remains constant or grows linearly with the number of modules because it is easier to implement a complex voter than a complex switch (voters have more regular structures). Extensive comparisons are made between different fault-tolerant techniques. A new reliability model is also developed for system reliability evaluation of the new designs. The results of these analyses are plotted, and the advantages of the new techniques are demonstrated. In the final part of the work an expert system is described which uses the knowledge acquired by these comparisons. This expert system is meant as a prototype of a component of a CAD tool which will act as an advisor on fault-tolerant techniques
A new mouse mutant, skijumper
Low blood sugar levels are a well-known cause of severe illness and often death in newborn humans, especially those that are small for age. Few of the causes of neonatal hypoglycemia are known, and many remain to be found. We describe a novel mouse mutant, skijumper (skimp), in which pups, despite feeding well, have low levels of glucose and develop opisthotonos, followed by death typically within a few days after birth. Genetic mapping studies have localized the lesion to a approximately 1 cM interval on mouse Chromosome (Chr) 7 between D7Mit318 and D7Mit93. We have carried out extensive analysis to define the phenotype and its likely cause. In addition to low blood glucose, affected skijumper mice have lowglycogen and ketone levels. Mass spectrometric analysis of blood samples has excluded major defects in amino acid metabolism. Initial biochemical analyses suggested a defect in ketogenesis as one possible cause of this phenotype. However, measurements of levels and activities of carnitine, carnitine palmitoyl transferases, and other enzymes involved in ketogenesis, along with studies of mitochondrial structure and function, did not demonstrate significant differences between skijumper, unaffected littermates, and control wild-type mice. These results indicate that abnormal enzyme activity in known pathways does not appear to be the primary biochemical lesion in skijumper. The skijumper may be a new valuable model for studying and understanding one type of neonatal morbidity and death