Predictors of severe hypoxemia among COVID-19 patients in Burkina Faso (West Africa): Findings from hospital based cross-sectional study

Introduction: COVID-19 is one of the world’s major health crises. The objective of this study was to determine the predictive factors of severe hypoxemia in patients hospitalized in COVID-19 health facilities in Burkina Faso. Patients and method: This study was a hospital-based cross-sectional study. The data collected relate to the period of the first wave of the epidemic (March 9 to June 30, 2020). All patients hospitalized for COVID-19 in the requisitioned health facilities of Ouagadougou were included in this study. Predictors of severe hypoxemia were identified using a multivariate logistic regression model. Results: During the study period, 442 patients were included, representing 45.7% of the total number of positive patients in the entire country. The most common co-morbidities were diabetes (55; 12.4%) and arterial hypertension (97; 21.9%). Severe hypoxemia (SpO2 < 90%) was observed in 64 patients (14.5%). Age over 65 years (OR = 8.24; 95% CI: 2.83–24.01) and diabetes (OR = 2.43; 95% CI: 1.17–5.06) were the predictors for occurrence of severe hypoxemia in multivariate analysis. Conclusion: The predictive factors of COVID-19 are similar in African and Caucasian populations. The surveillance of COVID-19 in risk groups should be strengthened to reduce their morbidity and mortality

Prise en charge de la COVID-19 à domicile à Ouagadougou au Burkina Faso au début de la pandémie (Résultats préliminaires)

Introduction : Face au nombre croissant de cas de refus d’hospitalisation d’une part et à la faiblesse des capacités d’hospitalisation d’autre part, le Burkina Faso a opté pour un programme de suivi des patients à domicile que nous étudions.Méthodologie : Il s’est agi d’une étude transversale descriptive du 16 avril au 20 mai 2020, à Ouagadougou des patients COVID-19 confirmés par PCR et pris en charge à domicile.Résultats : Au total 222 patients avec une COVID-19 ont été recensés dont 30 patients (13,5%) pris en charge à domicile. Le nombre moyen de suivi était de 3,45 visites, l’âge moyen était de 36,1 ± 16,7 ans et les enfants ainsi que les sujets de plus de 60 ans représentaient chacun 10% des cas. Parmi les patients, 60% étaient des célibataires et 22% avaient une comorbidité dont les plus fréquentes étaient le diabète (13,2%) et l’hypertension artérielle (6,7%). Les principaux symptômes étaient la toux (30,0%), l’asthénie physique (26,7%) et les céphalées (16,7%). Au cours du suivi, 33% des patients n’ont pas respecté le confinement à domicile : certains étaient absents et d’autres à leurs occupations sans port de masque ; Dans 10% des cas, les patients ont été hospitalisés et un décès a été constaté.Conclusion : Cette nouvelle pratique de prise en charge, si elle respecte certains critères d’éligibilité permettra de désengorger les structures sanitaires et offrirait plus de confort et de sérénité aux patients. &nbsp; English title: Home Care of COVID-19 in Burkina Faso at the Start of the pandemic (Preliminary Results)Background : Faced with the growing number of cases of refusal of hospitalization on the one hand and the weakness of hospitalization capacity on the other hand, Burkina Faso has opted for a home patient monitoring program, which we study.Methodology : This was a descriptive cross-sectional study carried out on COVID-19 patients confirmed by polymerase chain reaction and cared for at home from April 16 to May 20, 2020, in the city of Ouagadougou. Results : A total of 223 patients were identified in Ouagadougou, including 30 patients (13.5%) who were cared for at home. The mean number of follow-ups was 3.45 visits, average age was 36.1±16.7 years, children and people over 60 years in 10.0% of each. Of the patients, 60.0% were single and 22.0% had a comorbidity; the most common of which were diabetes (13.2%) and hypertension (6.7%). The main symptoms were cough (30.0%), physical asthenia (26.7%), and headache (16.7%). During follow-up, 33.0% did not adhere to containment at home: some of them were absents or doing theirs work without masque. Ten percent of patients takecare at home were hospitalized, and one death was recorded.Conclusion : If this new practice of home care meets certain eligibility criteria, it will relieve congestion at healthcare facilities and offer more comfort and serenity to patients