25 research outputs found

    Assessment of Ecological Status and Tree Diversity in Watershed Area of Dandi Local Government Area in Kebbi State, Nigeria

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    This study assessed the ecological and tree diversity status of watershed area of Dandi local government area in Kebbi state using systematic sampling technique. Three transects of 300 m long were laid at 100 m intervals. On each transect, six sample plots of size 50 m x 50 m (0.25ha) were alternately laid at 50 m intervals. A total of 18 sample plots will be used for the study. Diameters at breast height (Dbh) of all the trees found in the plot with Dbh ≥ 5cm will be measured. Fourteen tree species belonging to 10 genera and 8 families were identified. Borassus aethiopum of the family Arecaceae was the most abundant species in the area with a relative density (RD) and diversity index (DI) of 0.296 and 0.08728 respectively. This was followed by Cocos nucifera in the Arecaceae family also, with RD and DI of 0.192 and 0.03662 respectively. Daniella oliveri of the family Fabaceae was the least represented species with RD and DI of 0.0018 and 0.00002 respectively. The overall tree species richness in the area was 0.0052

    Description and Composition of Tree Species in a Tertiary Institution Agricultural Faculty Arboretum, Ibadan, South-West Nigeria

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    The Arboretum of the Agricultural Faculty of a tertiary institution in Ibadan is known for its rich diversity of trees. Therefore, the study investigates the tree growth variables in the arboretum such as diameter at breast height (dbh), diameter at the base, middle and top of the bole, total height, merchantable height and crown diameter. The basal area and volume were then calculated per species and per family. Several models were fitted for the height – diameter relationship and crown diameter – diameter relationship and crown diameter – dbh relationship. Positive linear relationships were observed among the growth variables. The fitted models showed that cubic models exhibit a more reliable function than quadratic and linear models for crown diameter – dbh predictions as it has R2 above 0.75. Endangered species were observed too and this was indicated through the diversity index obtained. The highest basal area encounter belongs to myrtaceae family (9.61m2) while the lowest belongs to pinaceae family (0.24m2). The total basal area obtained at (31.72m2) from the faculty trees indicates that they are exhibiting better growth and yield

    Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

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    BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes. METHODS: We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization. RESULTS: During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events. CONCLUSIONS: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)
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