The Herschel view of the environment of the radio galaxy 4C+41.17 at z = 3.8

We present Herschel observations at 70, 160, 250, 350 and 500 μm of the environment of the radio galaxy 4C+41.17 at z = 3.792. About 65 per cent of the extracted sources are securely identified with mid-infrared sources observed with the Spitzer Space Telescope at 3.6, 4.5, 5.8, 8 and 24 μm. We derive simple photometric redshifts, also including existing 850 and 1200 μm data, using templates of active galactic nuclei, starburst-dominated systems and evolved stellar populations. We find that most of the Herschel sources are foreground to the radio galaxy and therefore do not belong to a structure associated with 4C+41.17. We do, however, find that the spectral energy distribution (SED) of the closest (∼25 arcsec offset) source to the radio galaxy is fully consistent with being at the same redshift as 4C+41.17. We show that finding such a bright source that close to the radio galaxy at the same redshift is a very unlikely event, making the environment of 4C+41.17 a special case. We demonstrate that multiwavelength data, in particular on the Rayleigh–Jeans side of the SED, allow us to confirm or rule out the presence of protocluster candidates that were previously selected by single wavelength data setsPeer reviewe

Asymptomatic Pulmonary Hypertension in Systemic Lupus Erythematosus

Introduction Pulmonary arterial hypertension (PAH) is a serious and often fatal complication of systemic lupus erythematosus (SLE). Because the diagnosis of PAH often is made years after symptom onset, early diagnostic strategies are essential. Doppler echocardiography currently is considered the noninvasive screening test of choice for evaluating pulmonary hypertension. Aim Screening for asymptomatic pulmonary hypertension in systemic lupus erythematosus patients using Doppler echocardiography, and correlating it with inflammatory parameters of the disease. Patients and Methods Doppler echocardiography was performed in 74 patients with systemic lupus erythematosus over one year (66 adult and 8 juvenile), adult SLE included 57 patients with adult-onset and 9 patients with childhood-onset. Pulmonary hypertension was diagnosed if the peak systolic pressure gradient at the tricuspid valve was more than 30 mmHg. All patients were subjected to full history taking, rheumatological examination, laboratory studies and chest x-ray. Results In seventy four SLE patients, the pulmonary hypertension was detected in 8 patients (10.8%), 7 adult-onset SLE patients (aged from 19 to 30 years) and 1 juvenile SLE (aged 12 years). The range of pulmonary artery systolic pressure was 34–61.2 mmHg (43.19 ± 9.28). No significant differences between patients with and those without pulmonary hypertension as regard clinical features. Significantly higher frequencies of rheumatoid factor and anti-cardiolipin antibodies were found in patients with pulmonary hypertension versus those without ( P = 0.02, P = 0.008 respectively). Positive rheumatoid factor and ACL were significantly associated with occurrence of PAH in SLE ( P = 0.007, P = 0.006 respectively). No significant correlations were found between pulmonary artery pressure, disease duration, SLE Disease Activity Index (SLEDAI), ESR, and anti-ds DNA. Conclusion Patients with SLE have an increased risk of pulmonary arterial hypertension. Echocardiography should be used as a screening tool in patients at high risk for development of pulmonary hypertension. Positive anti-cardiolipin antibodies and rheumatoid factor were significant predictors of pulmonary hypertension in our study

The role of 18F-FDG-PET/CT in the management of patients with high-risk breast cancer: case series and guideline comparison

Objectives: In grade III-IV breast cancer, dissemination of disease needs to be assessed. Until now this was done by conventional imaging (liver ultrasonography, chest X-ray and bone scintigraphy), but evidence favoring the use of FDG-PET/CT is accumulating. Methods: Patients with high-risk breast cancer, who had received conventional imaging and FDG-PET/CT, were included. Patients were staged and assigned a treatment after 1) conventional imaging and 2) FDG-PET/CT, both by a multidisciplinary oncology team. Equivocal FDG-PET/CT findings were histologically confirmed. Results: 16 patients were included (mean age 59 years). TNM-stage changed in 5 patients (31%) after FDG-PET/CT. In 3 patients (19%) unknown distant metastases were detected by FDG-PET/CT. An adjustment of treatment took place in 4 patients (25%). Conclusions: Our case series emphasizes the role of FDG-PET/CT in the staging of high-risk breast carcinoma, especially in the assessment of distant metastases. We suggest replacing conventional imaging with FDG-PET/CT

Theory of c-axis Josephson tunneling in d-wave superconductors

The temperature and angular dependence of the c-axis Josephson current and the superfluid density in layered d-wave superconductors are studied within the framework of an extended Ambegaokar-Baratoff formalism. In particular, the effects of angle-dependent tunneling matrix elements and Andreev scattering at grain boundaries are taken into account. These lead to strong corrections of the low-temperature behavior of the plasma frequency and the Josephson current. Recent c-axis measurements on the cuprate high-temperature superconductors HgBa_2CaCu_{1+\delta} and Bi_2Sr_2CaCu_2O_{8+\delta} can therefore be interpreted to be consistent with a d-wave order parameter.Comment: Revtex, 4 pages with 4 eps figures, to appear in PRB R

The Numerical Renormalization Group Method for correlated electrons

The Numerical Renormalization Group method (NRG) has been developed by Wilson in the 1970's to investigate the Kondo problem. The NRG allows the non-perturbative calculation of static and dynamic properties for a variety of impurity models. In addition, this method has been recently generalized to lattice models within the Dynamical Mean Field Theory. This paper gives a brief historical overview of the development of the NRG and discusses its application to the Hubbard model; in particular the results for the Mott metal-insulator transition at low temperatures.Comment: 14 pages, 7 eps-figures include