Fault detection of redundant systems based on B-spline neural network

The fault detection and isolation of redundant sensor systems based on B-spline neural networks is presented in this paper. The network is trained using an algorithm with an adaptive learning rate. To further save computation time, the residual vector is transformed from a multivariate B-spline function to an univariate B-spline function. The detection of abrupt and drifting faults using the proposed method is discusses. The performance of the proposed method is illustrated by an example involving a redundant system consisting of six sensors.published_or_final_versio

Cytomegalovirus-associated colitis mimicking necrotizing enterocolitis – A near miss diagnosis of neonatal colonic stricture

Although cytomegalovirus (CMV) is a common congenital infection in neonates, most patients are asymptomatic. Gastrointestinal manifestation is unusual. In this report, we described a newborn with perinatal CMV infection presented with symptoms mimicking necrotizing enterocolitis. We hope to alert clinicians about this possible diagnosis when managing newborn gastrointestinal diseases.published_or_final_versio

Discoveries from a phenanthroline-based dynamic combinatorial library: catenane from a copper(I) or copper(II) template?

We report here a DCL study of a phenanthroline-based building block focusing on catenane formation with copper templates. Two [2]catenanes have been amplified by using Cu+ as a template from the DCLs that contain no interlocked compounds in the absence of copper. In addition, an unexpected Cu2+ template effect on the [2]catenane formation was discovered. The observed Cu2+ template effect was found to originate from the in situ reduction of the divalent metal to Cu+.postprin

Osteopontin in rheumatoid arthritis and osteoarthrits

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Self-help cognitive-behavioral therapy for insomnia (CBT-1): a systematic review of randomized controlled trials

Abstract Theme: Insomnia - new insight into development and manageThis study aimed to review current literature, examine the efficacy, adherence, acceptability, and attrition rate of self-help CBT-I, and to explore possible factors that might contribute to the effectiveness of the treatment. A systematic review was performed up to June 2012 on studies published in 6 major electronic databases. Two researchers performed study identification, data extraction, and methodological quality evaluation. Meta-analyses of self-help CBT-I vs. waiting-list, routine care, or no treatment, therapist-administered CBT-I, and placebo treatment were performed. We identified 20 randomized controlled trials (RCT) that met inclusion criteria. When compared to waiting-list control, self-help CBT-I achieved a moderate to large effect size on improving sleep and reducing sleep-related cognitions and anxiety and depressive symptoms. Therapist-administered CBT-I was slightly better than self-help CBT-I. Subgroup analyses supported the beneficial effect of telephone consultation, but not for “full” multi-component CBT and programs lasting for 6 or more weeks. Treatment adherence, acceptability, perceived usefulness, and credibility were reported as satisfactory. Based on the results of the systematic review, we have designed a Chinese-language self-help CBT-I and now conducting a RCT to evaluate the efficacy of Internet-based self-help CBT-I in Chinese population.postprin

The Health Benefits of Visual Art Activities in the Geriatric Population

Purpose: The purpose of this poster presentation is to assess the efficacy of visual art therapy on the physical and mental health of the geriatric population. Description: The potential impact of art therapy on cognition and dementia is a growing field of research in the rehabilitative world. Some researchers have found support for certain mediums, such as ceramic painting, while others have explored multimodal treatment programs that integrate art into physical activities. Combining physical activity with an arts and crafts program could posit a significant impact on ADL function and quality of life in older adults. As a growing list of ailments accompany aging, it would be of interest to explore the effects of visual art therapy on life satisfaction, cognitive status, ADLs, and levels of depression in older adults. Methods: A literature review was conducted on visual art activities and health in the geriatric population using the following search terms: art therapy, visual art, mental health, health, cognition, geriatric, and older adults. Five peer-reviewed studies that were published between 2016 and 2019 were selected for review. Conclusion: The current literature supports the inclusion of visual art therapy as treatment for older adults. Research shows that art therapy can decrease grief, mourning, negative emotions, and depression while promoting positive memories, socializing, language function and quality of life in older adults. Art therapy has also been correlated with positive effects on emotional status and cognitive status in patients with dementia. Summary of Use: This poster presentation reviews the benefits of implementing visual art therapy in geriatric rehabilitation in terms of both physical and mental health. Clinical Relevance: Visual art activities are low-intensity interventions that work to improve both gross motor and fine motor skills in the geriatric population. Art activities can specifically help address deficits of upper body strength, stability, proprioception, and tactile skills. In addition to physical improvements, participant engagement, mood, quality of life, and well-being are positively affected as well. Given the potential benefits, further research is needed to bolster support for the integration of visual art activities with traditional exercise.https://soar.usa.edu/casmspring2020/1001/thumbnail.jp

Development and Validation of the Chinese Attitudes to Starting Insulin Questionnaire (Ch-ASIQ) for Primary Care Patients with Type 2 Diabetes

Objectives: To develop and evaluate the psychometric properties of a Chinese questionnaire which assesses the barriers and enablers to commencing insulin in primary care patients with poorly controlled Type 2 diabetes. Research Design and Method: Questionnaire items were identified using literature review. Content validation was performed and items were further refined using an expert panel. Following translation, back translation and cognitive debriefing, the translated Chinese questionnaire was piloted on target patients. Exploratory factor analysis and item-scale correlations were performed to test the construct validity of the subscales and items. Internal reliability was tested by Cronbach's alpha. Results: Twenty-seven identified items underwent content validation, translation and cognitive debriefing. The translated questionnaire was piloted on 303 insulin naïve (never taken insulin) Type 2 diabetes patients recruited from 10 government-funded primary care clinics across Hong Kong. Sufficient variability in the dataset for factor analysis was confirmed by Bartlett's Test of Sphericity (P 0.4 and Eigenvalues >1. Total variance for the 10 factors was 66.22%. Kaiser-Meyer-Olkin measure was 0.725. Cronbach's alpha coefficients for the first four factors were ≥0.6 identifying four subscales to which 13 items correlated. Remaining sub-scales and items with poor internal reliability were deleted. The final 13-item instrument had a four scale structure addressing: 'Self-image and stigmatization'; 'Factors promoting self-efficacy; 'Fear of pain or needles'; and 'Time and family support'. Conclusion: The Chinese Attitudes to Starting Insulin Questionnaire (Ch-ASIQ) appears to be a reliable and valid measure for assessing barriers to starting insulin. This short instrument is easy to administer and may be used by healthcare providers and researchers as an assessment tool for Chinese diabetic primary care patients, including the elderly, who are unwilling to start insulin. © 2013 Fu et al.published_or_final_versio

A prospective interventional study to examine the effect of a silver alloy and hydrogel--coated catheter on the incidence of catheter-associated urinary tract infection

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Live birth following double-factor pre-implantation genetic diagnosis for both reciprocal translocation and alpha-thalassaemia

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