14,848 research outputs found
Multidecadal variability in hydro-climate of Okavango river system, southwest Africa, in the past and under future climate
The focus of this paper is to understand the multi-decadal oscillatory component of variability in the Okavango River system, in southwestern Africa, and its potential evolution through the 21st century under climate change scenarios. Statistical analyses and hydrological modelling are used to show that the observed multi-decadal wet and dry phases in the Okavango River and Delta result from multi-decadal oscillations in rainfall, which are likely to be related to processes of internal variability in the climate system, rather than external natural or anthropogenic forcing. Analyses of changes in this aspect of variability under projected climate change scenarios are based on data from a multi-model ensemble of 19 General Circulation Models, which are used to drive hydrological models of the Okavango River and Delta. Projections for the 21st century indicate a progressive shift towards drier conditions attributed to the influence of increasing temperatures on water balance. It is, however, highly likely that multi-decadal oscillations, possibly of similar magnitude to that of 20th century, will be superimposed on the overall trend. These may periodically offset or amplify the mean drying trend. This effect should be accounted for in water and catchment management and climate change adaptation strategies
SCREENING FOR HEPATITIS C Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified
This is the peer reviewed published version of the following article: Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified, which has been published in final form at 10.1136/bmj.h998. This article may be used for non-commercial purposes in accordance with BMJ's Terms and Conditions for Self-Archiving.This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/ by/4.0
A new method of observing weak extended x-ray sources with RHESSI
We present a new method, fan-beam modulation, for observing weak extended
x-ray sources with the Reuven Ramaty High-Energy Solar Spectroscopic Imager
(RHESSI). This space-based solar x-ray and gamma-ray telescope has much greater
sensitivity than previous experiments in the 3-25 keV range, but is normally
not well suited to detecting extended sources since their signal is not
modulated by RHESSI's rotating grids. When the spacecraft is offpointed from
the target source, however, the fan-beam modulation time-modulates the
transmission by shadowing resulting from exploiting the finite thickness of the
grids. In this paper we detail how the technique is implemented and verify its
consistency with sources with clear known signals that have occurred during
RHESSI offpointing: microflares and the Crab Nebula. In both cases the results
are consistent with previous and complementary measurements. Preliminary work
indicates that this new technique allows RHESSI to observe the integrated hard
x-ray spectrum of weak extended sources on the quiet Sun.Comment: Publishe
Gene-history correlation and population structure
Correlation of gene histories in the human genome determines the patterns of
genetic variation (haplotype structure) and is crucial to understanding genetic
factors in common diseases. We derive closed analytical expressions for the
correlation of gene histories in established demographic models for genetic
evolution and show how to extend the analysis to more realistic (but more
complicated) models of demographic structure. We identify two contributions to
the correlation of gene histories in divergent populations: linkage
disequilibrium, and differences in the demographic history of individuals in
the sample. These two factors contribute to correlations at different length
scales: the former at small, and the latter at large scales. We show that
recent mixing events in divergent populations limit the range of correlations
and compare our findings to empirical results on the correlation of gene
histories in the human genome.Comment: Revised and extended version: 26 pages, 5 figures, 1 tabl
The effect of topology on the structure and free energy landscape of DNA kissing complexes
We use a recently developed coarse-grained model for DNA to study kissing
complexes formed by hybridization of complementary hairpin loops. The binding
of the loops is topologically constrained because their linking number must
remain constant. By studying systems with linking numbers -1, 0 or 1 we show
that the average number of interstrand base pairs is larger when the topology
is more favourable for the right-handed wrapping of strands around each other.
The thermodynamic stability of the kissing complex also decreases when the
linking number changes from -1 to 0 to 1. The structures of the kissing
complexes typically involve two intermolecular helices that coaxially stack
with the hairpin stems at a parallel four-way junction
Nearby Optical Galaxies: Selection of the Sample and Identification of Groups
In this paper we describe the Nearby Optical Galaxy (NOG) sample, which is a
complete, distance-limited (6000 km/s) and magnitude-limited
(B14) sample of 7000 optical galaxies. The sample covers 2/3 (8.27
sr) of the sky () and appears to have a good completeness in
redshift (98%). We select the sample on the basis of homogenized corrected
total blue magnitudes in order to minimize systematic effects in galaxy
sampling.
We identify the groups in this sample by means of both the hierarchical and
the percolation {\it friends of friends} methods. The resulting catalogs of
loose groups appear to be similar and are among the largest catalogs of groups
presently available. Most of the NOG galaxies (60%) are found to be
members of galaxy pairs (580 pairs for a total of 15% of objects)
or groups with at least three members (500 groups for a total of
45% of objects). About 40% of galaxies are left ungrouped (field
galaxies). We illustrate the main features of the NOG galaxy distribution.
Compared to previous optical and IRAS galaxy samples, the NOG provides a denser
sampling of the galaxy distribution in the nearby universe. Given its large sky
coverage, the identification of groups, and its high-density sampling, the NOG
is suited for the analysis of the galaxy density field of the nearby universe,
especially on small scales.Comment: 47 pages including 6 figures. Accepted for publication in Ap
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